Major Depressive Disorder
📧 Sign up to get email alerts when something new happens for Major Depressive Disorder.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder [Phase 3]
Phase 3 study of CYB003, a deuterated psilocin analog, in adults with major depressive disorder is currently recruiting.
-
CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Understanding Music and Mindfulness Preferences in Psilocybin-Assisted Psychotherapy [Phase 2]
This Phase 2 study investigates how music and mindfulness preferences influence psilocybin-assisted psychotherapy for treatment-resistant ma…
-
CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 Diabetes [NA]
This clinical trial is evaluating cognitive-behavioral therapy and exercise training for adolescents at risk of type 2 diabetes, with focus …
-
CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Positive Processes and Transition to Health - Single-Session (PATH-SS) [NA]
A currently recruiting clinical trial named PATH-SS (Single-Session PATH) at Case Western Reserve University is evaluating an intervention f…
-
CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Defining Neurobiological Links Between Substance Use and Mental Illness [NA]
A clinical trial sponsored by the National Institute on Drug Abuse to investigate neurobiological links between substance use and mental ill…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Teen Vulnerability to Irritability: Brain and Estrogen Changes [Phase 4]
This Phase 4 clinical trial update from the University of North Carolina investigates brain and estrogen changes related to irritability in …
-
CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Sound Bite-- a Therapeutic Song-writing Program [NA]
A clinical trial in Hong Kong is evaluating Sound Bite, a therapeutic song-writing program for depression, with recruitment ongoing.
-
CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Mindfulness-Based Stress Reduction Training Program Model [NA]
A clinical trial update describing a mindfulness-based stress reduction program for depression and anxiety, currently not recruiting.
-
CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Clinical Efficacy, Safety, and Applicability of Home-based Bright Light Therapy in Outpatient Adolescents With Major Depressive Disorder [NA]
This entry describes an ongoing clinical trial evaluating home-based bright light therapy for adolescents with major depressive disorder, fo…
-
CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of Ketamine [EARLY_Phase 1]
A pilot Phase 1 trial from the University of Pennsylvania is recruiting to investigate glutamatergic changes associated with ketamine's rapi…
-
CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Treatment for Migraine and Mood [NA]
A clinical trial led by Amanda Shallcross studying treatment for migraine and depressive symptoms is currently active but not recruiting.
-
CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Transcranial Photobiomodulation (tPBM) for Somatic Symptoms in Treatment-Resistant Depression [NA]
The document reports ongoing recruitment for a clinical trial using transcranial photobiomodulation to address somatic symptoms in treatment…
-
CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Prospective Assessment of Cost-effectiveness and Side-effects of Depressive Patients Treated With ECT or TCA
A prospective study comparing cost-effectiveness and side effects of electroconvulsive therapy and tricyclic antidepressants in patients wit…
-
CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Venous Tourniquet vs. Arterial Tourniquet for Seizure Monitoring in ECT [NA]
Clinical trial comparing venous versus arterial tourniquet use for seizure monitoring during electroconvulsive therapy; the study targets ad…
-
CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Neural Response to Inflammatory Challenge in Major Depressive Disorder [Phase 1, Phase 2]
Ongoing Phase 1/2 clinical trial assessing neural response to an inflammatory challenge in adults with Major Depressive Disorder; recruitmen…
-
CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: The STEP-MIED Trial: Digital Stepped-Care for Emotional Disorders [NA]
STEP-MIED is a clinical trial exploring digital stepped-care for emotional disorders, including major depressive disorder, anxiety disorders…
-
CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Pilot Randomized Trial of BA-GSH in VA PC-MHI [NA]
Pilot randomized trial of BA-GSH for depression in VA Primary Care–Mental Health Integration (PC-MHI) is currently not yet recruiting. The s…
-
CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Development and Multicenter Validation of an AI-Based Remote Photoplethysmography (rPPG) Facial Scan for Multimodal Health Assessment
This trial update covers the development and multicenter validation of an AI-based remote photoplethysmography (rPPG) facial scan for multim…
-
CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Improving Brain Stimulation Through Imaging
Clinical trial update describing research on improving brain stimulation through imaging for depression. The study includes treatment-resist…
-
CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Evaluation of a Keto-Like Supplement on Brain Responses to Emotional Stimuli in Depression [Phase 2]
A Phase 2 clinical trial is evaluating a keto-like dietary supplement on brain responses to emotional stimuli in people with depression. The…
-
CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Promoting Mental Health of Teachers and Caregiver Using a Personalized mHealth Toolkit in Uganda [NA]
A trial update shows recruitment is ongoing for a study in Uganda to promote mental health among teachers and caregivers using a personalize…
-
CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Cognitive Training as an Adjunct to Ketamine in Real-world Clinics [NA]
A clinical trial is evaluating cognitive training as an adjunct to ketamine for depression in real-world clinics; the study is currently enr…
-
CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Tracking Brain Biomarkers and Renormalization Associated With Antidepressant Transcranial Magnetic Stimulation Therapy
Clinical trial update on tracking brain biomarkers and renormalization associated with antidepressant transcranial magnetic stimulation ther…
-
CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Implementing Action-Based Cognitive Remediation for Transdiagnostic Cognitive Difficulties in a Tertiary Mental Health Hospital [NA]
This clinical trial update describes a study at The Royal Ottawa Mental Health Centre testing action-based cognitive remediation for transdi…
-
CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Enhancing Health in Rural Populations: Music as Therapy [NA]
Northern Arizona University is conducting a clinical trial to evaluate music therapy for stress, generalized anxiety, chronic pain, and depr…