Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Parent Encouragement And Coaching of Happiness in Youth [NA]
This clinical trial, sponsored by the University of Pittsburgh, evaluates a parent-focused program to improve happiness in youth with depres…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Accelerated vs. Conventional Theta Burst Stimulation for Late-life Depression [NA]
A clinical trial is evaluating accelerated versus conventional theta burst stimulation for late-life depression and is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Psychiatric Genotype/Phenotype Project Repository
Clinical trial update from Vanderbilt University describing a psychiatric genotype/phenotype project repository. The study is currently enro…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Digital Cognitive Behavioral Therapy for Chinese Adolescents With Depressive Symptoms（CADS-D ) [NA]
A clinical trial is evaluating a digital cognitive behavioral therapy program (CADS-D) for depressive symptoms in Chinese adolescents, and t…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: NQ Square TMS for MDD 1Dx3S Adults Multi-site Sham-controlled Protocol [NA]
This clinical trial update reports an ongoing sham-controlled study evaluating NQ Square transcranial magnetic stimulation for adults with m…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Effect of Esketamine on Perioperative Negative Emotions in Patients Undergoing Breast Cancer Surgery [NA]
This clinical trial is evaluating whether esketamine reduces perioperative negative emotions in patients undergoing breast cancer surgery an…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: The Effectiveness and Efficacy of an Online Cognitive Behavioral Psychotherapeutic Program [NA]
An ongoing clinical trial evaluating the effectiveness and efficacy of an online cognitive behavioral therapy program for depression and anx…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Factorial Optimization Trial to Test Effects of Coping Intervention Components [NA]
This clinical trial update describes an active but not recruiting factorial study from Arizona State University to evaluate the effects of c…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD) [Phase 1, Phase 2]
The STAR-AD study, a Phase 1/Phase 2 trial exploring sequenced treatment alternatives for adolescent depression, is currently recruiting and…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: A Text Messaging Intervention to Reduce Perinatal Depression Risk [NA]
A completed clinical trial evaluated a text messaging intervention aimed at reducing the risk of perinatal depression, focusing on major dep…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Identity-Based Transdiagnostic Therapy for Young People With Anxiety and Depression [NA]
Clinical trial update on identity-based transdiagnostic therapy for anxiety and depression in young people; currently recruiting.
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Home-Based Transcranial Direct Current Stimulation In Major Depressive Disorder (HOME) [NA]
A clinical trial update for home-based transcranial direct current stimulation in major depressive disorder, currently recruiting.
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Amplitude Titration to Improve ECT Clinical Outcomes [NA]
This clinical trial update notes that the University of New Mexico is conducting a study on amplitude titration to improve electroconvulsive…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Supporting Peer Interactions to Expand Access to Digital Cognitive Behavioral Therapy for Spanish-speaking Patients [NA]
An ongoing UC Irvine study is exploring peer-support enhancements to expand access to digital cognitive behavioral therapy for Spanish-speak…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Effectiveness of the SoundHeal Multi-Sensory Integrative Therapy Among Justice-Involved Youth [NA]
Clinical trial update indicates the SoundHeal Multi-Sensory Integrative Therapy is currently recruiting for justice-involved youth, evaluati…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Gaze Contingent Attentional Reinforcement in Major Depressive Disorder [NA]
Tel Aviv University is conducting a study on gaze-contingent attentional reinforcement as an intervention for Major depressive disorder, wit…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder [Phase 2]
An ongoing Phase 2 clinical trial at McLean Hospital is evaluating the efficacy and safety of magnesium with vitamin B6 for individuals with…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Mindfulness-based Intervention for Depressive Symptoms Sent Via Text (MINDSET) [NA]
Clinical trial update for Mindfulness-based Intervention for Depressive Symptoms Sent Via Text (MINDSET) assessing a text-based mindfulness …
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Emotion Focused Family Therapy for Parents of Children With Mental Health Difficulties [NA]
A clinical trial update about Emotion Focused Family Therapy for parents of children with anxiety, depression, and behavioral problems, curr…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Imagery Rescripting in Primary Care [NA]
A clinical trial update indicates that the University of Amsterdam-sponsored study on imagery rescripting in primary care is recruiting part…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Mind-Body Skills Group for Graduate Students [NA]
A Cornell-sponsored clinical trial is evaluating a mind-body skills group for graduate students to address mood changes, depressive symptoms…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Gut Microbiota in IBD With Comorbid Depressive Disorder
A clinical trial studying the relationship between gut microbiota and inflammatory bowel disease with comorbid depressive disorder is curren…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetic Characteristics of (R)-Ketamine Hydrochloride Nasal Spray in Patients With Depression and Acute Suicidal Ideation or Behavior [Phase 2]
Phase 2 study to evaluate the efficacy, safety, and pharmacokinetics of an R-ketamine hydrochloride nasal spray in adults with major depress…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Enhancing Operational Readiness With Digital Self-Managed Cognitive Behavioral Therapy for Insomnia (CBTI) [NA]
Clinical trial update for a digital self-managed cognitive behavioral therapy for insomnia (CBT-I) study aimed at enhancing operational read…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Unmute's CARE Framework: A Novel Approach to Strengthen the Therapeutic Alliance and Reduce Treatment Disparities [NA]
New York University is evaluating Unmute's CARE Framework to strengthen the therapeutic alliance and reduce disparities in depression and an…