Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Psychostimulant Augmentation of Repetitive TMS for the Treatment of Major Depressive Disorder [EARLY_Phase 1]
This document updates on an early Phase 1 clinical trial investigating whether psychostimulant augmentation can enhance repetitive transcran…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: An Open-Label Study of Azetukalner in Major Depressive Disorder [Phase 3]
An open-label Phase 3 clinical trial evaluating azetukalner for Major Depressive Disorder is currently enrolling by invitation.
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Feasibility of a Technology-Based Intervention for Depression Referral Uptake in Cancer Survivors [NA]
A feasibility study is recruiting to test a technology-based intervention designed to improve uptake of depression referrals among cancer su…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: No Time to Wait: Single Session Intervention [NA]
Clinical trial update for a single-session intervention study sponsored by United Christian Hospital, evaluating depression (major depressiv…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Effects of Jin Shin Jyutsu-Based Hand Application on Quality of Life and Psychosocial Status in Perimenopausal Women [NA]
This clinical trial update describes a study evaluating Jin Shin Jyutsu-based hand application for improving quality of life and psychosocia…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Resolving Early Life Stress: Psychotherapy Outcomes and Neurobiology in Complex Depression [NA]
A clinical trial is recruiting to examine psychotherapy outcomes and neurobiological changes in adults with major depressive disorder associ…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Impact of Depression on Thermoregulation
A Penn State University clinical trial is recruiting to study how depression affects thermoregulation.
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Filipino Family Health Initiative 1.0 [NA]
Kaiser Permanente is conducting a clinical trial called Filipino Family Health Initiative 1.0, currently recruiting to study depression, anx…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Modular Intervention for Depression Study [NA]
The clinical trial studying a modular intervention for major depressive disorder is listed as not yet recruiting. It is sponsored by Pontifi…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Effectiveness of Integrated Network for Student Psychosocial Intervention, Resilience, and Education (INSPIRE) on Mental Health Outcomes Among Indonesian Adolescents in Bandung [NA]
This clinical trial update describes the INSPIRE program, evaluating a school-based psychosocial intervention to improve mental health outco…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Expressive Writing on Minority Stressors Among Sexual Minority Veterans [NA]
This is a registered clinical trial evaluating expressive writing to address minority stressors in sexual minority veterans, focusing on dep…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Psilocybin to Treat Depression in Spinal Cord Injury [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating psilocybin for depression in individuals with spinal cord injury is listed as not yet recruiting. The st…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Effects of EMDR on Psychological Symptoms and EEG Findings in Trauma-Exposed Individuals [NA]
A clinical trial update describing a study on EMDR therapy’s effects on psychological symptoms and EEG results in trauma-exposed individuals…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Promoting Resilience in Stroke Survivor-carepartner Dyads (ReStoreD) [NA]
An active, not-recruiting clinical trial from the University of Utah called ReStoreD, investigating resilience-promoting interventions for s…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Real-world Clinical Response to Trazodone in Italy, Poland, and Romania
A real-world clinical trial is recruiting to assess trazodone's clinical response in adults with major depressive disorder and cognitive dis…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Association Analysis of Depression and Asthma
An observational clinical trial in Shanghai is planned to analyze the association between depression and asthma. The study is not yet recrui…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Biomarkers of Depression and Treatment Response [NA]
A clinical trial exploring biomarkers of depression and treatment response, currently recruiting.
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Occupational Therapy for Mental Health and Engagement in Neurorehabilitation [NA]
An ongoing ClinicalTrials.gov trial at Colorado State University is evaluating occupational therapy to support mental health and engagement …
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Effects of a Black Rice Extract and Anthocyanidin Metabolites on the Synthesis and Release of BDNF in Healthy Subjects [NA]
This clinical trial investigates whether a black rice extract and its anthocyanidin metabolites affect the synthesis and release of brain-de…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Brain STimulation for ANxiety and Depression in Youth [NA]
An ongoing clinical trial at the University of Calgary is evaluating brain stimulation for anxiety disorders and depression in youth and is …
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Dopaminergic Therapy for Anhedonia - 2 [Phase 4]
Phase 4 clinical trial conducted by Emory University is evaluating a dopaminergic therapy for anhedonia and depression, and is currently rec…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Effect of Continuous Intraoperative Esketamine Infusion on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Mild-to-Severe Depression [NA]
This clinical trial investigates whether continuous intraoperative esketamine infusion can reduce perioperative negative emotions in patient…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Home-Based tDCS for Depression in BPD [NA]
A clinical trial evaluating home-based transcranial direct current stimulation (tDCS) for depression in individuals with Borderline Personal…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Brief Culturally Adapted Behavioral Activation Therapy for Adults With Depression in Rural Indonesian Primary Care: A Type-2 Hybrid Effectiveness-Implementation Trial [NA]
This clinical trial protocol describes a Type-2 Hybrid effectiveness-implementation study evaluating Brief Culturally Adapted Behavioral Act…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: MOSAIC (MOthers' AdvocateS In the Community) for Pregnant Women and Mothers of Children Under 5 With Experience of Intimate Partner Violence [NA]
A clinical trial update for MOSAIC, a study focused on pregnant women and mothers with experience of intimate partner violence, currently ac…