Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Dynamic Network Response to TMS Treatment
A Goethe University-sponsored clinical trial is investigating dynamic network responses to transcranial magnetic stimulation for major depre…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Fluoxetine on Emotional Experience (FLEX) Study [NA]
A clinical trial investigating fluoxetine's effect on emotional experience in adults with major depressive disorder and irritability; recrui…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: A Study of ONO-1110 in Patients With Major Depressive Disorder [Phase 2]
Clinical trial update indicates Ono Pharmaceutical's ONO-1110 is in Phase 2 testing for major depressive disorder and is currently not recru…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Personalizing Mental Health Treatment for Youth and Families [NA]
Clinical trial update from the University of Oregon on personalizing mental health treatment for youth and families. The study is not yet re…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Abbreviated MBCT for Depression in Older African American/Black Breast Cancer Survivors [NA]
This entry reports an active, non-recruiting clinical trial evaluating abbreviated MBCT to treat depression in older African American/Black …
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Bridging the Gap: Implementing BRIDGES [NA]
Clinical trial update from Université Catholique de Louvain on implementing the BRIDGES program for depression in inactive people; the study…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Feasibility and Acceptability of Peer Intervention for Improving Mental Health Among People Accessing Hormone Care [NA]
This ClinicalTrials.gov update describes a feasibility and acceptability study of a peer intervention to improve mental health among people …
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Pilot Effectiveness Trial of an ACT Self-help Workbook Tailored Specifically for Prisons [NA]
Pilot effectiveness trial of an ACT self-help workbook tailored for prisons, evaluating its impact on anxiety and depression.
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Michigan Men's Diabetes Project III(MenDIII): Mind and Motion [NA]
A University of Michigan trial called MenDIII Mind and Motion is currently recruiting participants with type 2 diabetes and depressive sympt…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: START NOW Adapted: Culturally Adapted Version of START NOW [NA]
This clinical trial update indicates that the START NOW Adapted, a culturally adapted version of the START NOW program, is currently recruit…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Computerized Cognitive Behavioral Therapies for Suicide Prevention and Depression [Phase 2]
A Phase 2 clinical trial evaluating computerized cognitive behavioral therapies for suicide prevention and depression is currently recruitin…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Evaluation of Association Between Testosterone Levels, Dementia, and Adverse Mental Health Outcomes
This clinical trial update examines whether testosterone levels are associated with dementia and adverse mental health outcomes, including a…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Real-World NeuroModulate: Investigating Non-Invasive Brain Stimulation for Neuropsychiatric Disorders at TUM
Real-World NeuroModulate at Technical University of Munich is investigating non-invasive brain stimulation for depressive disorders and is c…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Evaluation of the Concordance Between Measures Obtained by a Medical Device for Emotional Monitoring (EMOCARE) and the Patient Health Questionnaire (PHQ-9) Score in Patients With Mild to Severe Depressive Episode [NA]
This clinical trial aims to evaluate how well measurements from the EMOCARE emotional monitoring device concord with PHQ-9 scores in patient…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Epidemiological Study on the Prevalence of Mental Disorders in Slovakia
A completed epidemiological study from Comenius University assessing the prevalence of several mental disorders in Slovakia.
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Clinician Supported Mobile App to Reduce Mental Health Symptoms Among World Trade Center Responders in Florida [NA]
This clinical trial evaluates a clinician-supported mobile app intended to reduce PTSD, anxiety, depression, and sleep disturbance symptoms …
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Virtual Reality in Hemodialysis to Improve Psychological Well-being [NA]
This ClinicalTrials.gov update describes a study evaluating virtual reality during hemodialysis to improve psychological well-being in patie…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Mechanisms Of Change in Psychotherapy: The Effects of Cognitive Behavioral Therapy and Psychodynamic Therapy in Once - Versus Twice - Weekly Sessions on Outcomes in Depression. [NA]
A clinical trial protocol assessing mechanisms of change in psychotherapy, comparing cognitive-behavioral therapy and psychodynamic therapy …
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Interest of Adaptated Physical Activity (APA) on the K Recovery Constant, Reflecting the Rate of Muscle Oxygenation Recovery in Menopausal Women Suffering From Depression [NA]
This clinical trial update indicates ongoing research on adapted physical activity to improve muscle oxygenation recovery in menopausal wome…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: GynMDD Add-On to Supportive Psychotherapy in Mild to Moderate Depression [NA]
ClinicalTrials.gov entry for an add-on intervention called GynMDD Add-On to Supportive Psychotherapy for mild-to-moderate depression is NOT_…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness [Phase 2]
A Phase 2 clinical trial update from Brigham and Women's Hospital seeks novel transcranial magnetic stimulation targets for psychiatric illn…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence Study [Phase 3]
Phase 3 comparative effectiveness study comparing esketamine (Spravato) to ketamine for depression is currently recruiting to assess equival…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Changing Lives and Changing Outcomes-9 at Worcester Recovery Center and Hospital [NA]
A Massachusetts General Hospital-sponsored clinical trial at Worcester Recovery Center and Hospital is currently recruiting. The study targe…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: To Investigate the Change of Brain and Autonomic Function From Different Protocols of Repeated Transcranial Magnetic Stimulation Therapy for Patients With Post-traumatic Stress Disorder Comorbid Major Depressive Disorder [NA]
A clinical trial evaluating different protocols of repetitive transcranial magnetic stimulation (rTMS) to assess brain and autonomic functio…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: The Role of mGluR5 in CBT-I [Phase 4]
A Phase 4 clinical trial update investigating the role of mGluR5 modulation in CBT-I for adults with Major depressive disorder, currently re…