Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Transdiagnostic Cognitive Biomarkers [NA]
University of Minnesota is updating a clinical trial on transdiagnostic cognitive biomarkers related to pain and depression, currently recru…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Neurostimulation Versus Therapy for Problems With Emotions [NA]
A Duke University-sponsored trial is comparing neurostimulation to therapy for problems with emotion regulation across mood and anxiety diso…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Group Intervention for Interpersonal Skills [NA]
This clinical trial update notes a Charité University-led study on a group interpersonal skills intervention for depressive and anxiety diso…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Efficacy and Safety of Accelerated Intermittent Theta-burst Stimulation (a-iTBS) in Adolescents With Depressive Disorder [NA]
A clinical trial is evaluating the efficacy and safety of accelerated intermittent theta-burst stimulation for adolescents with major depres…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Exercise-priming of CBT for Depression: the CBT+ Trial [NA]
This clinical study is investigating exercise-primed cognitive behavioral therapy for major depressive disorder (the CBT+ Trial). Recruitmen…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Treatment of Depression Post-SCI [NA]
A clinical trial investigating treatment of depression after spinal cord injury is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Intracranial Investigation of Neural Circuity Underlying Human Mood [NA]
A Baylor College of Medicine–sponsored intracranial study examining neural circuitry underlying mood is currently recruiting for depression …
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Prospective Cohort Study of Response and Tolerability of Accelerated Intermittent Theta-burst Stimulation (1W-AiTBS)
Prospective cohort study evaluating response and tolerability of accelerated intermittent theta-burst stimulation (1W-AiTBS) for depression.…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Mindfulness-based Psilocybin Therapy for PTSD [Phase 2]
Phase 2 clinical trial evaluating mindfulness-based psilocybin therapy for post-traumatic stress disorder and major depressive disorder; sta…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Cannabis, Linked Emotions, and Adolescent Risk Study [NA]
A Massachusetts General Hospital clinical trial investigating cannabis use, linked emotions, depression, suicidal ideation, and adolescent b…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Using TMS to Understand Neural Processes of Social Motivation [NA]
Clinical trial update: Auburn University is recruiting participants to study neural processes of social motivation. The study lists social a…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: 40 Hz Light Neurostimulation for Patients With Depression (FELIX) [NA]
Ongoing clinical trial evaluating 40 Hz light neurostimulation for adults with major depressive disorder and treatment-resistant depression.…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: University of Iowa Interventional Psychiatry Service Patient Registry
This clinical trial registry entry from the University of Iowa Interventional Psychiatry Service is recruiting participants for a patient re…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Efficacy of a Culturally-adapted Mediterranean Diet Intervention on Depression in Relation to the Gut Microbiome [NA]
A clinical trial sponsored by the Chinese University of Hong Kong will assess whether a culturally-adapted Mediterranean diet can affect dep…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Pattern Separation in Major Depressive Disorder [Phase 1]
Phase 1 clinical trial investigating pattern separation in Major Depressive Disorder; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: A Study to Explore the Effect of SP-624 on Brain Network Analytics in Healthy Adults and Adults With Major Depression [Phase 1]
This clinical trial update indicates SP-624 is being studied in Phase 1 to assess its effects on brain network analytics in healthy adults a…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Accelerated Treatment of Depressive Patients With tDCS [NA]
This clinical trial, sponsored by the University of Regensburg, investigates accelerated transcranial direct current stimulation (tDCS) as a…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Collaborative Care for Anxiety and Depression in Epilepsy [NA]
A recruiting clinical trial from Wake Forest University Health Sciences tests collaborative care for anxiety and depression in people with e…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: An Integrative, Digital Health Approach to Veteran-Centered PTSD Care [NA]
A clinical trial from Texas A&M evaluating an integrative digital health approach to veteran-centered PTSD care; enrollment is by invitation…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Tidal Model-Based ACT for Depression [NA]
A Baskent University-sponsored clinical trial is evaluating tidal model-based ACT for major depressive disorder, with status listed as NOT_Y…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Neuroimaging Markers of Midlife Depression and Cognitive Behavioural Therapy (CBT) [NA]
This clinical trial entry examines neuroimaging markers of midlife depression and the effectiveness of cognitive behavioral therapy, with th…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use [NA]
A preliminary efficacy trial is underway to evaluate a digital intervention for depression and cannabis use disorder. The study is currently…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Improving the Treatment of Depression Among Youth With HIV [NA]
This clinical trial update describes a study aimed at improving the treatment of depression among youth living with HIV, which is currently …
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Optimized Predictive Treatment In Medications for Unipolar Major Depression (OPTIMUM-D) [Phase 4]
Phase 4 trial OPTIMUM-D investigating optimized predictive treatment for unipolar major depression is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: NUTRIMOOD-Inflammation and Depressive Comorbidity in Obesity: Modulation by Omega-3 Polyunsaturated Fatty Acids Status [NA]
This clinical trial in Taiwan investigates whether omega-3 fatty acid status modulates inflammation and depressive symptoms in obesity among…