Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: ASHA Bangladesh--An Integrated Intervention to Address Poverty and Depression [NA]
A clinical trial in Bangladesh tests an integrated intervention to address poverty and depression, with recruitment ongoing and a focus on m…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Perioperative Negative Emotions in Breast Cancer Surgery Patients [NA]
A clinical trial evaluating whether transcutaneous auricular vagus nerve stimulation can affect perioperative negative emotions in breast ca…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: MAGNESIUM & SSRI VS SSRI ALONE AMONG PATIENTS OF MAJOR DEPRESSIVE DISORDER [Phase 2]
Phase 2 trial comparing magnesium augmentation to SSRI therapy versus SSRI alone in adults with major depressive disorder; the study is curr…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Development and Validation of Psycho-Social Program (PSP) [NA]
Development and validation of a psycho-social program (PSP) for mental health outcomes, with the study currently not recruiting.
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Group Cognitive Evolutionary Therapy for Depression [NA]
This document reports an ongoing clinical trial on Group Cognitive Evolutionary Therapy for depression and anxiety, currently active but not…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: A Study to Assess the Skin Irritation and Sensitization of Selegiline TDS in Healthy Subjects [Phase 1]
A Phase 1 study to evaluate skin irritation and sensitization of the selegiline transdermal system in healthy subjects; Major depressive dis…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Fluoxetine and Understanding Social Experiences [NA]
Clinical trial assessing fluoxetine's antidepressant activity in healthy volunteers and its effects on social experiences in adolescents wit…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors [NA]
A ClinicalTrials.gov update indicates a trial of Adaptive Coping Skills Training to reduce psychological distress among survivors of cardior…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Contribution of Virtual Reality Eye Tracking in the Identification of Schizophrenia, Bipolar and Depression [NA]
This ongoing clinical trial explores whether virtual reality eye tracking can help identify schizophrenia, bipolar disorder, and major depre…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Efficacy of Transcutaneous Auricular Vagus Nerve Stimulation on Alleviating Major Depressive Disorder in Patients With Acute Coronary Syndrome After Percutaneous Coronary Intervention:A Prospective, Double-Blind,Randomized Controlled Study [NA]
Prospective, double-blind, randomized trial assessing whether transcutaneous auricular vagus nerve stimulation can reduce depressive symptom…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Effects of an Innovative TCM-based Tui Jing Therapy on Psychological and Neurophysiological Functions in Depression [NA]
A clinical trial evaluating the effects of a traditional Chinese medicine–based Tui Jing therapy on psychological and neurophysiological fun…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Profiling Vulnerability and Resilience for Mental Illness Following Viral Infections: Translating Epidemiology to Deep-phenotyping.
This ClinicalTrials.gov update describes a study examining how prior viral infections influence susceptibility and resilience to mental illn…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: A Patient Activation Approach to Implementing Depression Treatment in Cardiac Patients [NA]
Columbia University is testing a patient-activation approach to implementing depression treatment in patients with cardiovascular disease; t…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: The Oh Happy Day Class - Digital Connections (OHDC-DC): A Pilot Study [NA]
Pilot clinical trial update for The Oh Happy Day Class - Digital Connections (OHDC-DC) sponsored by the University of Wisconsin–Madison, stu…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: ACE-D Aim 3 Clinical Cognitive Trial to Enhance Translation in Depression [Phase 2]
Phase 2 clinical trial update from Stanford on ACE-D Aim 3 to enhance translation in depression. Recruitment is ongoing.
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Promoting Teenage Sleep for Improved Mental Health and School Performance [NA]
A recruiting clinical trial from Kristianstad University aims to promote teenage sleep to improve mental health and school performance, inve…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Social Media Intervention for Online Victimized Youth [NA]
This update describes an ongoing clinical trial at the University of Pittsburgh testing a social media–based intervention to help youth expe…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: ACT_for Alcohol Use Disorder and Depression [NA]
Clinical trial update for ACT for Alcohol Use Disorder and Depression (NCT06620276) indicating the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: A Novel Blood Test as a Biomarker in Mental Health
This clinical trial investigates a novel blood test biomarker for mental health conditions. The study (NCT06856161) is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Brain Network Mechanisms of Cognitive Impairments in Major Psychiatric Disorders and Their Clinical Applications [NA]
A clinical trial exploring brain network mechanisms underlying cognitive impairments across schizophrenia, bipolar disorder, and major depre…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Participatory System Dynamics vs Usual Quality Improvement: Staff Use of Simulation as an Effective, Scalable and Affordable Way to Improve Timely Mental Health Care? [NA]
This is an update on a completed VA-sponsored trial comparing participatory system dynamics modeling with usual quality improvement to impro…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Self Neuro-modulation Therapy for Major Depressive Disorder (MDD) With Anhedonia [NA]
A clinical trial is currently recruiting to evaluate self neuro-modulation therapy for major depressive disorder with anhedonia.
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Visual Frailty in Ageing
University of Edinburgh-sponsored clinical trial is currently recruiting to study visual frailty in aging, examining how frailty and age-rel…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Technology-Assisted Implementation of a Mobile Health Program for Serious Mental Illness [NA]
This entry reports a completed clinical trial from the University of Washington evaluating technology-assisted implementation of a mobile he…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Amygdala Neurofeedback for Depression - Large Scale Clinical Trial [NA]
A large-scale clinical trial is recruiting to evaluate amygdala neurofeedback as a treatment for Major Depressive Disorder.