Major Depressive Disorder with Psychotic Features
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Cognitive Strategies in Early Psychosis 2 [Phase 3]
A Phase 3 clinical trial from the University of Minnesota evaluating cognitive strategies in early psychosis, currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Impact of Medication Education on Adherence and Side Effects [NA]
A clinical trial update from Cumhuriyet University studying whether medication education improves adherence and reduces side effects in schi…
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CLINICAL_TRIALS trial_result · 2025-12-26Clinical Trial Update: Adapting and Examining Collaborative Decision Skills Training Among Veterans With Serious Mental Illness [NA]
This update reports the completion of a VA-sponsored clinical trial evaluating collaborative decision skills training for veterans with seri…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Academic-Community EPINET (AC-EPINET) [NA]
Clinical trial update for the Academic-Community EPINET (AC-EPINET) study led by Indiana University; the trial status is completed and it in…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: MI-CBTech: A Mobile Intervention for Community Integration in Homeless-Experienced Veterans With SMI [NA]
This clinical trial assesses MI-CBTech, a mobile intervention aimed at improving community integration for homeless-experienced veterans wit…
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CLINICAL_TRIALS research · 2025-08-21Clinical Trial Update: EPI-MINN: Targeting Cognition and Motivation - National [NA]
An update on the EPI-MINN trial from the University of Minnesota evaluating cognition and motivation in several psychotic disorders; the stu…
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: Multi-modal Assessment of Gamma-aminobutyric Acid (GABA) Function in Psychosis [Phase 4]
A Phase 4 clinical trial assessing gamma-aminobutyric acid (GABA) function in psychosis has completed.
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: Minnesota Community-Based Cognitive Training in Early Psychosis [NA]
Update on the completed clinical trial of Minnesota's community-based cognitive training for people with early psychosis; results have been …
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CLINICAL_TRIALS research · 2024-05-14Clinical Trial Update: The Efficacy of Metacognitive Skills Training in the Context of Forensic Psychiatric Care [NA]
This entry reports on a clinical trial evaluating metacognitive skills training for individuals in forensic psychiatric care, with recruitme…
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CLINICAL_TRIALS trial_result · 2017-04-27Clinical Trial Update: Anomalous Self-Experience in First Episode Psychosis - A Six-Year Follow-Up Study
A six-year follow-up update from a clinical trial studying anomalous self-experience in first-episode psychosis, reporting long-term outcome…
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: Treatment of Psychotic Major Depression With Mifepristone [Phase 3]
A Phase 3 trial evaluating mifepristone for psychotic major depression was terminated, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-02-16Clinical Trial Update: A Study of Mifepristone vs. Placebo in the Treatment of Patients With Major Depression With Psychotic Features [Phase 3]
Phase 3 trial of mifepristone vs placebo for major depressive disorder with psychotic features was terminated; results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-02-13Clinical Trial Update: Risks for Insulin Resistance and Metabolic Syndrome Between Major Depressive Disorder (MDD) or MDD With Psychotic Features
This terminated clinical trial investigated the risk of insulin resistance and metabolic syndrome in individuals with major depressive disor…
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CLINICAL_TRIALS trial_result · 2016-03-28Clinical Trial Update: Seroquel Alone Versus Seroquel With an SSRI for Depression With Psychotic Symptoms [Phase 4]
A Phase 4 trial comparing quetiapine alone versus quetiapine with an SSRI for major depressive disorder with psychotic features was terminat…
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CLINICAL_TRIALS trial_result · 2016-02-08Clinical Trial Update: Psychosis: Early Detection, Intervention and Prevention [NA]
Clinical trial update from MaineHealth reports completion and posted results for a study on psychosis focusing on early detection, intervent…
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CLINICAL_TRIALS trial_result · 2016-01-28Clinical Trial Update: Reducing Internalized Stigma in People With Serious Mental Illness [Phase 2]
Phase 2 trial update evaluating an intervention to reduce internalized stigma in people with serious mental illness, including schizophrenia…
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CLINICAL_TRIALS trial_result · 2015-11-26Clinical Trial Update: A Study to Determine the Efficacy and Safety of 2 Doses of Org 34517 as Adjunctive Therapy in Subjects With Psychotic Major Depression (28130)(P05845) [Phase 2]
Phase 2 trial update for Org 34517 as adjunctive therapy in psychotic major depression; the study has completed evaluating two doses for eff…
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CLINICAL_TRIALS research · 2015-10-14Clinical Trial Update: Clinical Validation of the Rating Scale for Psychotic Depression (RAS-PD)
Clinical trial update reporting the validation of the Rating Scale for Psychotic Depression (RAS-PD) for assessing symptoms in psychotic dep…
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CLINICAL_TRIALS trial_result · 2013-08-02Clinical Trial Update: Study of Pharmacotherapy of Psychotic Depression [Phase 3]
Phase 3 trial update on pharmacotherapy for psychotic depression sponsored by Weill Medical College of Cornell University; the study on majo…
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CLINICAL_TRIALS trial_result · 2013-06-04Clinical Trial Update: Ziprasidone vs. Sertraline/Haloperidol in Psychotic Depression [Phase 2, Phase 3]
This entry reports an update on a Phase 2/3 trial comparing ziprasidone to the sertraline/haloperidol combination for psychotic depression, …
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CLINICAL_TRIALS trial_result · 2013-01-24Clinical Trial Update: Quetiapine in the Treatment of Psychotic Depression - a Pilot Study [Phase 3]
This document reports the completion of a Phase 3 pilot trial evaluating quetiapine for psychotic depression.
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CLINICAL_TRIALS trial_result · 2012-08-20Clinical Trial Update: The Combination of Aripiprazole and Antidepressants in Psychotic Major Depression [Phase 3]
This report notes the completion of a Phase 3 trial evaluating aripiprazole in combination with antidepressants for psychotic major depressi…
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CLINICAL_TRIALS trial_result · 2012-02-15Clinical Trial Update: A United States Extension Study of Corlux for Recurrent Psychotic Symptoms in Psychotic Major Depression [Phase 3]
This document notes the completion of a United States extension study of Corlux for recurrent psychotic symptoms in major depressive disorde…
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CLINICAL_TRIALS trial_result · 2009-06-12Clinical Trial Update: Recovery Guide Intervention for Recurrent Psychiatric Hospitalization [NA]
This clinical trial evaluating a Recovery Guide Intervention for recurrent psychiatric hospitalization has completed, sponsored by Yale Univ…
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CLINICAL_TRIALS withdrawal · 2008-01-10Clinical Trial Update: Treatment of Depression With Quetiapine [Phase 3]
A Phase 3 trial evaluating quetiapine for major depressive disorder with psychotic features was terminated. The update notes the status but …