Lymphoma B-cell
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Sign up freeTop drugs studied for this disease
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EMA approval · 2026-08-06EMA Authorised: Zynlonta (loncastuximab tesirine) — Swedish Orphan Biovitrum AB
EMA authorised Zynlonta (loncastuximab tesirine) for certain B-cell lymphomas with a conditional approval.
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CLINICAL_TRIALS trial_result · 2025-07-02Clinical Trial Update: Retreatment With CTL019/CTL119 [Phase 1]
Phase 1 trial update regarding retreatment with CTL019/CTL119 for B-cell lymphoma; the study status is NOT_YET_RECRUITING.
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: Magnetic Resonance Imaging in Immune Effector Cell-Associated Neurotoxicity Syndrome [NA]
This document provides an update on a completed clinical trial evaluating magnetic resonance imaging in immune effector cell-associated neur…
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CLINICAL_TRIALS trial_result · 2024-02-14Clinical Trial Update: DA-EPOCH-R Induction Followed by Nivolumab Consolidation in Newly Diagnosed MYC, BCL2 and/or BCL6 Rearranged HGBL [Phase 2]
Phase 2 trial evaluating DA-EPOCH-R induction followed by nivolumab consolidation in newly diagnosed high-grade B-cell lymphoma with MYC, BC…
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CLINICAL_TRIALS trial_result · 2023-12-29Clinical Trial Update: Targeting CD19 and CD22 CAR-T Cells Immunotherapy in Patients With Relapsed or Refractory B Cell Lymphoma [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating CAR-T cells targeting CD19 and CD22 for relapsed or refractory B-cell lymphoma.
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CLINICAL_TRIALS trial_result · 2023-06-07Clinical Trial Update: A Phase 1/2 Study To Evaluate ASN002 In Relapsed/Refractory Lymphoma And Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial update for ASN002 in relapsed/refractory lymphoma and advanced solid tumors; the study status is TERMINATED with re…
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CLINICAL_TRIALS trial_result · 2023-05-24Clinical Trial Update: ASTRAL- a Clinical Study to Assess the Efficacy and Toxicity of High-dose Chemotherapy [Phase 2]
Phase 2 clinical trial update assessing high-dose chemotherapy for aggressive non-Hodgkin lymphoma and related lymphomas; study is completed…
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CLINICAL_TRIALS withdrawal · 2023-04-21Clinical Trial Update: A Study of Zilovertamab and Ibrutinib in Patients With Relapsed or Refractory Mantle Cell Lymphoma [Phase 3]
A Phase 3 trial combining Zilovertamab with Ibrutinib for relapsed or refractory mantle cell lymphoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2023-04-18Clinical Trial Update: CD19+Targeted CAR-T Cell Therapy for Relapsed/Refractory CD19+ B Cell Leukemia and Lymphoma [Phase 1, Phase 2]
Phase 1/2 clinical trial update for a CD19-targeted CAR-T cell therapy in relapsed/refractory CD19+ B-cell leukemias and lymphomas.
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CLINICAL_TRIALS trial_result · 2022-12-14Clinical Trial Update: Safety and Efficacy of Sequential CD19 and CD22 Targeted CAR-T Therapy for Relapsed/Refractory B Cell Lymphoma [Phase 1, Phase 2]
A clinical trial update on sequential CD19 and CD22-targeted CAR-T therapy for relapsed/refractory B cell lymphoma across Phase 1 and Phase …
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CLINICAL_TRIALS trial_result · 2022-04-07Clinical Trial Update: Rituximab and Pegylated Interferon α-2b in Patients With Indolent B-cell Lymphoma [Phase 2]
Phase 2 trial evaluating rituximab in combination with pegylated interferon α-2b for indolent B-cell lymphoma is under investigation with st…
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CLINICAL_TRIALS trial_result · 2021-08-19Clinical Trial Update: Treatment of Non-Hodgkin's Lymphoma With 90Y-hLL2 IgG [Phase 1, Phase 2]
Phase 1/2 trial update for 90Y-hLL2 IgG in Non-Hodgkin's Lymphoma shows completed status.
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CLINICAL_TRIALS trial_result · 2021-05-07Clinical Trial Update: Study of CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell [Phase 1]
Phase 1 study updating on CAR-20/19-T cells in relapsed/refractory B-cell lymphomas; results posted after completion.
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CLINICAL_TRIALS trial_result · 2021-05-04Clinical Trial Update: T Cells Expressing a Fully-human AntiCD19 Chimeric Antigen Receptor for Treating B-cell Malignancies [Phase 1]
Phase 1 trial evaluating a fully-human anti-CD19 CAR-T cell therapy for treating B-cell malignancies, with completed status and posted resul…
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CLINICAL_TRIALS trial_result · 2019-11-15Clinical Trial Update: Safety and Efficiency Study of CD19-PD1-CART Cell in Relapsed/Refractory B Cell Lymphoma [Phase 2]
Phase 2 clinical trial update evaluating CD19-PD1-CART Cell therapy for relapsed/refractory B cell lymphoma.
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CLINICAL_TRIALS trial_result · 2019-11-05Clinical Trial Update: R2 and Combination Chemotherapy Versus R and Combination Chemotherapy in Newly Diagnosed Highly Aggressive B-NHL [Phase 4]
Phase 4 trial update comparing R2 and combination chemotherapy versus R and combination chemotherapy in newly diagnosed highly aggressive B-…
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CLINICAL_TRIALS trial_result · 2019-08-02Clinical Trial Update: Study Evaluating Chemotherapy in Combination With Inotuzumab Ozogamicin In Subjects With Non-Hodgkin's Lymphoma [Phase 1]
Phase 1 study evaluating chemotherapy in combination with inotuzumab ozogamicin in subjects with B-cell lymphoma (non-Hodgkin's lymphoma) ha…
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CLINICAL_TRIALS trial_result · 2019-05-17Clinical Trial Update: Treatment Study of Denintuzumab Mafodotin (SGN-CD19A) Plus RICE Versus RICE Alone for Diffuse Large B-Cell Lymphoma [Phase 2]
Phase 2 trial comparing denintuzumab mafodotin plus RICE versus RICE alone in diffuse large B-cell lymphoma; the study is terminated with re…
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CLINICAL_TRIALS trial_result · 2019-04-23Clinical Trial Update: Improving the Outcome of High-risk Aggressive B-cell Lymphoma Patients With Nivolumab Maintenance Therapy [Phase 2]
Phase 2 trial exploring nivolumab maintenance therapy to improve outcomes in high-risk aggressive B-cell lymphoma patients.
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CLINICAL_TRIALS trial_result · 2018-10-31Clinical Trial Update: Proteasome Inhibitor PS-341 Relapsed or Refractory B Cell Lymphomas Previously Treated With Chemotherapy [Phase 2]
Phase 2 clinical trial update for a proteasome inhibitor in relapsed or refractory B-cell lymphomas previously treated with chemotherapy.
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CLINICAL_TRIALS trial_result · 2018-10-26Clinical Trial Update: Study Evaluating CMC-544 In B-Cell Non-Hodgkin's Lymphoma [Phase 1]
Phase 1 trial evaluating CMC-544 in B-cell non-Hodgkin's lymphoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2016-06-10Clinical Trial Update: Rituxan/BEAM vs Bexxar/BEAM in Autologous Hematopoietic Stem Cell Transplant for Non-Hodgkin's Lymphoma (BMTCTN0401) [Phase 3]
Phase 3 trial comparing Rituxan/BEAM versus Bexxar/BEAM in autologous stem cell transplantation for non-Hodgkin lymphoma has completed with …
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CLINICAL_TRIALS trial_result · 2015-09-07Clinical Trial Update: Bone Marrow Transplant From Partially Matched Donors and Nonmyeloablative Conditioning for Blood Cancers (BMT CTN 0603) [Phase 2]
Phase 2 clinical trial update on bone marrow transplantation from partially matched donors with nonmyeloablative conditioning for various bl…
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CLINICAL_TRIALS trial_result · 2015-08-28Clinical Trial Update: Evaluating the Safety and Effectiveness of an Umbilical Cord Blood Stem Cell Transplant (BMT CTN 0604) [Phase 2]
Phase 2 clinical trial evaluating safety and effectiveness of an umbilical cord blood stem cell transplant for various hematologic malignanc…