Lupus Nephritis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2025-04-06Clinical Trial Update: A Study of TAK-007 in Adults With Refractory Lupus Nephritis (LN) or Refractory Systemic Sclerosis (SSc) [Phase 1]
A Phase 1 study of TAK-007 in adults with refractory lupus nephritis or refractory systemic sclerosis has been withdrawn.
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Repository of Novel Analytes Leading to Autoimmune, Inflammatory and Diabetic Nephropathies (RENAL AID)
Clinical trial RENAL AID from The Rogosin Institute is investigating novel analytes linked to autoimmune, inflammatory, and diabetic nephrop…
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: Chimeric Antigen Receptors T Cells for Refractory/Recurrent Lupus Nephritis in Children [Phase 3]
This document updates on a Phase 3 clinical trial evaluating CAR-T cell therapy for refractory or recurrent lupus nephritis in children, whi…
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CLINICAL_TRIALS research · 2025-03-31Clinical Trial Update: Systemic Lupus Erythematosus and Chlordecone Impregnation in Martinique
A clinical trial in Martinique is evaluating chlordecone impregnation for systemic lupus erythematosus with renal involvement; recruitment i…
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Equecabtagene Autoleucel Injection (Eque-cel) for Relapsed/Refractory Systemic Lupus Erythematosus (SLE) [NA]
Clinical trial update indicates ongoing recruitment for Equecabtagene autoleucel (Eque-cel), a CAR-T therapy, for relapsed/refractory system…
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Study of Daxdilimab (HZN-7734) in Participants With Active Proliferative Lupus Nephritis (LN) [Phase 2]
Phase 2 study of daxdilimab (HZN-7734) in active proliferative lupus nephritis was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2025-03-07Clinical Trial Update: ACTHar in the Treatment of Lupus Nephritis [Phase 4]
A Phase 4 trial of Acthar Gel for lupus nephritis has been terminated, and results have been posted. The study sponsor is Columbia Universit…
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: Predictors of Bone Mineral Density in Lupus Nephritis Activity
Assiut University is conducting a clinical trial to identify predictors of bone mineral density in patients with lupus nephritis activity; t…
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: Phase II Study Assessing Safety and Efficacy of APL-2 in Glomerulopathies [Phase 2]
Phase II trial of APL-2 in glomerulopathies completed; results have been posted.
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CLINICAL_TRIALS withdrawal · 2025-02-10Clinical Trial Update: A Study of IMPT-514 in Active Refractory Lupus Nephritis (LN) and Systemic Lupus Erythematosus (SLE) [Phase 1, Phase 2]
Lyell Immunopharma's IMPT-514 trial in active refractory lupus nephritis and systemic lupus erythematosus has been withdrawn (Phase 1/Phase …
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Systemic Immune Inflammatory Index in Systemic Lupus Erythematosus
A clinical trial investigating the Systemic Immune Inflammatory Index in patients with Systemic Lupus Erythematosus and Lupus Nephritis is c…
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CLINICAL_TRIALS research · 2025-01-21Clinical Trial Update: CD19/BCMA CAR-T Cell Therapy for Refractory/Relapsed Lupus Nephritis [EARLY_Phase 1]
This update notes an early-phase Phase 1 trial of CD19/BCMA CAR-T cell therapy for refractory/relapsed lupus nephritis that is currently rec…
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CLINICAL_TRIALS trial_result · 2025-01-10Clinical Trial Update: Long-term Follow-up for Evaluating the Safety of CS20AT04 in Subject with Lupus Nephritis
Long-term safety data for CS20AT04 in lupus nephritis were collected from a completed study, with follow-up safety results reported.
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CLINICAL_TRIALS trial_result · 2025-01-03Clinical Trial Update: Renal Resistive Index as an Indicator of Lupus Nephritis Severity and Systemic Lupus Activity [NA]
A completed clinical trial investigating whether the renal resistive index can indicate lupus nephritis severity and systemic lupus activity…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: SGLT2 Inhibitor in Lupus Nephritis Patients With Chronic Kidney Disease [Phase 2]
This document reports a Phase 2 clinical trial evaluating an SGLT2 inhibitor in patients with lupus nephritis and chronic kidney disease. Th…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Urinary Congophilia as an Indicator of Activity of Lupus Nephritis
The study investigates urinary congophilia as a potential biomarker of lupus nephritis activity; the trial status is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: Pre-emptive Treatments in Lupus Nephritis Patients With Serological Reactivation [NA]
Completed clinical trial evaluating pre-emptive treatments in lupus nephritis patients with serological reactivation. Conducted by The Unive…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: The Effect of Mycophenolate Mofetil and Cyclophosphamide on the Lymphocyte Subsets in Patients With Proliferative Lupus Nephritis [NA]
A clinical trial investigates how the combination of mycophenolate mofetil and cyclophosphamide affects lymphocyte subsets in patients with …
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: Mycophenolic Acid Pharmacokinetics and Pharmacogenomics in Lupus Nephritis
A completed clinical study evaluating how mycophenolic acid is processed in the body and how genetic factors may influence its pharmacokinet…
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CLINICAL_TRIALS trial_result · 2024-11-29Clinical Trial Update: Zanubrutinib in Participants With Active Proliferative Lupus Nephritis [Phase 2]
A Phase 2 trial of zanubrutinib in participants with active proliferative lupus nephritis has completed.
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: US Zamto-cel Autoimmune Diseases [Phase 1]
Miltenyi Biomedicine reports a Phase 1 trial of Zamto-cel for autoimmune diseases including lupus nephritis, systemic lupus erythematosus, s…
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: The Effect of Curcumin on the Clinical Outcome of Pediatric Patients with Active Lupus Nephritis [Phase 2]
Phase 2 pediatric trial evaluating curcumin for active lupus nephritis has completed.
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: High Quality Evidence of Guangzhou Lupus Nephritis Cohort (HOPE Cohort)
This update concerns the HOPE Cohort study of lupus nephritis in Guangzhou; the trial is currently recruiting and sponsored by the First Aff…
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CLINICAL_TRIALS research · 2024-11-08Clinical Trial Update: Universal CAR-T Cell Therapy for Refractory Lupus Nephritis [EARLY_Phase 1]
An early-phase trial evaluating universal CAR-T cell therapy for refractory lupus nephritis is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-11-01Clinical Trial Update: A Study to Compare the Efficacy and Safety of Tacrolimus Capsules and Cyclophosphamide Injection in Treatment of Lupus Nephritis [Phase 3]
Phase 3 trial comparing tacrolimus capsules with cyclophosphamide injection for lupus nephritis has completed.