Lupus Nephritis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Efficacy and Safety of Tacrolimus Versus Mycophenolate in Lupus Nephritis [Phase 3]
A Phase 3 clinical trial comparing tacrolimus with mycophenolate mofetil in lupus nephritis has completed, evaluating efficacy and safety ou…
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: LUPKYNIS Drug-use Results Survey
This ClinicalTrials.gov update describes a drug-use results survey for LUPKYNIS (voclosporin) in lupus nephritis, and the trial is currently…
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CLINICAL_TRIALS withdrawal · 2025-09-19Clinical Trial Update: CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy, in Patients With Refractory Systemic Lupus Erythematosus (GALLOP) [Phase 1]
This Phase 1 trial investigating a CRISPR-edited allogeneic anti-CD19 CAR-T cell therapy for systemic lupus erythematosus has been withdrawn…
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Weaning of Immunosuppression in Nephritis of Lupus [Phase 3]
A Phase 3 study evaluating the weaning of immunosuppression in lupus nephritis has completed.
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Per-protocol Repeat Kidney Biopsy in Incident Cases of Lupus Nephritis [NA]
This entry describes a clinical trial evaluating per-protocol repeat kidney biopsy in incident lupus nephritis cases; the study is currently…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: The Relation of Albumin/Globulin Ratio and Platelet/Albumin Ratio to Lupus Nephritis
A clinical trial evaluating whether albumin/globulin ratio and platelet/albumin ratio serve as biomarkers in Lupus Nephritis; the study is n…
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Obe-cel in Severe, Refractory Systemic Lupus Erythematosus With Active Lupus Nephritis [Phase 2]
Phase 2 trial update for obe-cel in patients with severe, refractory systemic lupus erythematosus and active lupus nephritis; the study is c…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Treatment of Lupus Nephritis With Allogeneic Mesenchymal Stem Cells [Phase 2]
A Phase 2 clinical trial evaluating allogeneic mesenchymal stem cells for lupus nephritis, currently recruiting.
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Daratumumab to Treat Active Lupus Nephritis [Phase 2]
A Phase 2 trial is investigating daratumumab for active lupus nephritis, and the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Evaluation of the Tolerance, Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of MIL62 Injection for Treating Lupus Nephritis [Phase 1, Phase 2]
Clinical trial update for MIL62 injection in lupus nephritis reporting tolerance, safety, pharmacokinetics, pharmacodynamics, and preliminar…
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FDA approval · 2025-06-27FDA Approved: MYHIBBIN — Supplemental Application (Azurity Pharmaceuticals, Inc.)
FDA approved a supplemental application for MYHIBBIN (mycophenolate mofetil) submitted by Azurity Pharmaceuticals, Inc. The supplement perta…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: SGLT-2 Inhibitors on Albuminuria in Chronic Kidney Disease Patients With Lupus Nephritis and ANCA- Associated Vasculitis [Phase 4]
Phase 4 clinical trial evaluating the impact of SGLT-2 inhibitors on albuminuria in chronic kidney disease patients with lupus nephritis and…
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CLINICAL_TRIALS trial_result · 2025-06-24Clinical Trial Update: A Prospective Observational Registry of Patients Treated With LUPKYNIS® (Voclosporin) in the US
This is a prospective observational registry of lupus nephritis patients treated with LUPKYNIS (voclosporin) in the United States, and the s…
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Correlation Between Serum Uric Acid, Serum Homocysteine Level and Interleukin- 17 in Lupus Nephritis Patients
A recruiting clinical trial examining the relationships between serum uric acid, serum homocysteine, and interleukin-17 levels in patients w…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: The BCMA/CD19 Dual Targeted CAR-T Cell in Participants With Autoimmune Kidney Diseases [Phase 1]
Phase 1 clinical trial evaluating a BCMA/CD19 dual-targeted CAR-T cell therapy for autoimmune kidney diseases, currently recruiting.
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: MSC303 Subcutaneous Injection for the Treatment of Immunologic Glomerular Disease. [Phase 1, Phase 2]
MSC303 is being studied as a subcutaneous injection for lupus nephritis and ANCA-associated glomerulonephritis in Phase 1/Phase 2 trials, wi…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: NK010 or NK042 in Combination With Rituximab for Refractory Systemic Lupus Erythematosus/Lupus Nephritis [Phase 1]
A Phase 1 clinical trial evaluating NK010 or NK042 in combination with Rituximab for refractory systemic lupus erythematosus and refractory …
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CLINICAL_TRIALS withdrawal · 2025-05-23Clinical Trial Update: Atacicept in Subjects With Active Lupus Nephritis (COMPASS) [Phase 3]
A Phase 3 trial evaluating atacicept in active lupus nephritis has been withdrawn (COMPASS), with no results reported.
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: S100A8 in Serum and Urine as a New Biomarker in Lupus Nephritis
This clinical trial update reports on S100A8 levels in serum and urine as a potential biomarker for lupus nephritis. The study status is com…
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: A Clinical Study of YTS109 Cell in R/R Systemic Lupus Erythematosus [Phase 1]
A Phase 1 clinical study evaluating YTS109 cells in relapsed/refractory systemic lupus erythematosus, including lupus nephritis and immune t…
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CLINICAL_TRIALS trial_result · 2025-05-07Clinical Trial Update: Evaluation of Patients With Lupus Nephritis Using Kidney MRI (Magnetic Resonance Imaging)
Trial update reporting the termination of a Johns Hopkins University study evaluating kidney MRI in patients with systemic lupus erythematos…
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CLINICAL_TRIALS withdrawal · 2025-04-24Clinical Trial Update: A Study to Evaluate the Safety and Preliminary Efficacy of ATA3219 in Participants With Systemic Lupus Erythematosus [Phase 1]
A Phase 1 study evaluating the safety and preliminary efficacy of ATA3219 in systemic lupus erythematosus and lupus nephritis has been withd…
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CLINICAL_TRIALS withdrawal · 2025-04-20Clinical Trial Update: A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G [Phase 2]
Phase 2 trial of ADX-097 for IgA nephropathy, lupus nephritis, and C3 glomerulopathy has been withdrawn.
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CLINICAL_TRIALS trial_result · 2025-04-18Clinical Trial Update: Study of EQ001 (Itolizumab) in Systemic Lupus Erythematosus With or Without Active Proliferative Nephritis [Phase 1]
Phase 1 study of EQ001 (Itolizumab) in systemic lupus erythematosus with or without active proliferative nephritis has completed and posted …
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: Cardio Renal Effects of SGLT2 Inhibitors Among Lupus Nephritis Patients [Phase 4]
Phase 4 trial update assessing cardio-renal effects of SGLT2 inhibitors in lupus nephritis patients; results have been posted.