Lupus Nephritis
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CLINICAL_TRIALS trial_result · 2025-05-07Clinical Trial Update: Evaluation of Patients With Lupus Nephritis Using Kidney MRI (Magnetic Resonance Imaging)
Trial update reporting the termination of a Johns Hopkins University study evaluating kidney MRI in patients with systemic lupus erythematos…
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CLINICAL_TRIALS trial_result · 2025-04-18Clinical Trial Update: Study of EQ001 (Itolizumab) in Systemic Lupus Erythematosus With or Without Active Proliferative Nephritis [Phase 1]
Phase 1 study of EQ001 (Itolizumab) in systemic lupus erythematosus with or without active proliferative nephritis has completed and posted …
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: Cardio Renal Effects of SGLT2 Inhibitors Among Lupus Nephritis Patients [Phase 4]
Phase 4 trial update assessing cardio-renal effects of SGLT2 inhibitors in lupus nephritis patients; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Study of Daxdilimab (HZN-7734) in Participants With Active Proliferative Lupus Nephritis (LN) [Phase 2]
Phase 2 study of daxdilimab (HZN-7734) in active proliferative lupus nephritis was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2025-03-07Clinical Trial Update: ACTHar in the Treatment of Lupus Nephritis [Phase 4]
A Phase 4 trial of Acthar Gel for lupus nephritis has been terminated, and results have been posted. The study sponsor is Columbia Universit…
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: Phase II Study Assessing Safety and Efficacy of APL-2 in Glomerulopathies [Phase 2]
Phase II trial of APL-2 in glomerulopathies completed; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-01-10Clinical Trial Update: Long-term Follow-up for Evaluating the Safety of CS20AT04 in Subject with Lupus Nephritis
Long-term safety data for CS20AT04 in lupus nephritis were collected from a completed study, with follow-up safety results reported.
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CLINICAL_TRIALS trial_result · 2025-01-03Clinical Trial Update: Renal Resistive Index as an Indicator of Lupus Nephritis Severity and Systemic Lupus Activity [NA]
A completed clinical trial investigating whether the renal resistive index can indicate lupus nephritis severity and systemic lupus activity…
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: Pre-emptive Treatments in Lupus Nephritis Patients With Serological Reactivation [NA]
Completed clinical trial evaluating pre-emptive treatments in lupus nephritis patients with serological reactivation. Conducted by The Unive…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: Mycophenolic Acid Pharmacokinetics and Pharmacogenomics in Lupus Nephritis
A completed clinical study evaluating how mycophenolic acid is processed in the body and how genetic factors may influence its pharmacokinet…
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CLINICAL_TRIALS trial_result · 2024-11-29Clinical Trial Update: Zanubrutinib in Participants With Active Proliferative Lupus Nephritis [Phase 2]
A Phase 2 trial of zanubrutinib in participants with active proliferative lupus nephritis has completed.
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: The Effect of Curcumin on the Clinical Outcome of Pediatric Patients with Active Lupus Nephritis [Phase 2]
Phase 2 pediatric trial evaluating curcumin for active lupus nephritis has completed.
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CLINICAL_TRIALS trial_result · 2024-11-01Clinical Trial Update: A Study to Compare the Efficacy and Safety of Tacrolimus Capsules and Cyclophosphamide Injection in Treatment of Lupus Nephritis [Phase 3]
Phase 3 trial comparing tacrolimus capsules with cyclophosphamide injection for lupus nephritis has completed.
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Tacrolimus With Steroid in Korean Lupus Nephritis Patients [Phase 4]
A Phase 4 clinical trial evaluating tacrolimus with steroids for lupus nephritis in Korean patients has been terminated.
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CLINICAL_TRIALS trial_result · 2024-10-22Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Tacrolimus for Lupus Nephritis Under Actual Use Situations
A completed clinical trial evaluating the safety and efficacy of tacrolimus for lupus nephritis in actual-use conditions.
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: SGLT2 Inhibitors Between Reno Protective Effects and Impact on Bone and Mineral Disease Among Lupus Nephritis Patients [Phase 4]
Phase 4 clinical trial evaluating the renoprotective effects of SGLT2 inhibitors and their impact on bone health in lupus nephritis patients…
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: Study of Safety, Efficacy and Tolerability of Secukinumab Versus Placebo, in Combination With SoC Therapy, in Patients With Active Lupus Nephritis [Phase 3]
A Phase 3 study evaluating secukinumab plus standard of care versus placebo in active lupus nephritis was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: A Study of Telitacicept in Lupus Nephritis [Phase 2]
Phase 2 study of Telitacicept for lupus nephritis is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-08-30Clinical Trial Update: Open-label Extension Study of Efficacy, Safety and Tolerability of Secukinumab in Patients With Active Lupus Nephritis [Phase 3]
Open-label extension study evaluating secukinumab for active lupus nephritis was terminated; results were posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: A Study of ANX009 in Adult Participants With Lupus Nephritis [Phase 1]
A Phase 1 study of ANX009 in adults with lupus nephritis has completed.
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: Safety, Pharmacokinetics and Preliminary Efficacy Study of CFZ533 in Patients With Lupus Nephritis. [Phase 2]
Phase 2 study evaluating safety, pharmacokinetics and preliminary efficacy of CFZ533 in lupus nephritis has completed, with results posted o…
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CLINICAL_TRIALS trial_result · 2024-04-16Clinical Trial Update: A Study of Guselkumab in Participants With Active Lupus Nephritis [Phase 2]
Phase 2 study evaluating guselkumab for active lupus nephritis was terminated, with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-03-08Clinical Trial Update: A Study of KZR-616 in Patients With SLE With and Without Lupus Nephritis [Phase 1, Phase 2]
Kezar Life Sciences completed a Phase 1/2 study of the immunoproteasome inhibitor KZR-616 in systemic lupus erythematosus with and without l…
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CLINICAL_TRIALS trial_result · 2023-11-02Clinical Trial Update: Assessment of Safety and Efficacy of SGLT2is Among LN Patients [Phase 1, Phase 2]
Phase 1/2 trial updating safety and efficacy of SGLT2 inhibitors in lupus nephritis.
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CLINICAL_TRIALS trial_result · 2023-07-06Clinical Trial Update: Comparing Mescaline Sodium Enteric-coated Tablets vs Morte-mescaline in the Treatment of Adult Lupus Nephritis [Phase 4]
Phase 4 clinical trial comparing Mescaline Sodium enteric-coated tablets with Morte-mescaline for adult Lupus Nephritis; status currently UN…