Lupus Nephritis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Efficacy and Safety of CD19 CAR-γδ T Cells in the Treatment of Relapsed/Refractory Autoimmune Nephropathy [EARLY_Phase 1]
Clinical trial update for a Phase 1 study of CD19 CAR-γδ T cells in relapsed/refractory autoimmune nephropathy, targeting membranous nephrop…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: SELECT-SLE: Biomarker-Guided CAR-T Target Selection for Refractory Lupus [Phase 1, Phase 2]
This clinical trial update describes SELECT-SLE, a Phase 1/2 study of biomarker-guided CAR-T target selection for refractory systemic lupus …
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Safety Study of IgAN, LN, MN, & C3 Glomerulopathy Including Dense Deposit Disease Treated With OMS721 [Phase 2]
Omeros' Phase 2 safety study of OMS721 in immunoglobulin A nephropathy, lupus nephritis, membranous nephropathy, and C3 glomerulopathy inclu…
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: An Open-label, Study to Assess Safety, Efficacy and Cellular Kinetics of YTB323 in Severe, Refractory Systemic Lupus Erythematosus [Phase 1, Phase 2]
This is an open-label Phase 1/2 trial to evaluate the safety, efficacy, and cellular kinetics of YTB323 in adults with severe, refractory sy…
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: Safety and Efficacy of ES-NK Cell Injection in the Treatment of Refractory Lupus Nephritis: an Early Clinical Study [EARLY_Phase 1]
Early Phase 1 clinical trial assessing the safety and potential efficacy of ES-NK cell injections for refractory lupus nephritis; the study …
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Voclosporin in Adolescent and Pediatric Subjects With Lupus Nephritis [Phase 3]
A phase 3 trial of voclosporin in adolescent and pediatric lupus nephritis has been terminated. The study was sponsored by Aurinia Pharmaceu…
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Long-Term Voclosporin Treatment in Adolescent and Pediatric Subjects With Lupus Nephritis [Phase 3]
A Phase 3 trial evaluating long-term voclosporin for lupus nephritis in adolescents and pediatric patients was terminated.
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CLINICAL_TRIALS trial_result · 2026-02-02Clinical Trial Update: Comparing Efficacy and Safety of Telitacicept and Belimumab in Lupus Nephritis: A Retrospective Multicenter Cohort Study.
A retrospective multicenter cohort study comparing the efficacy and safety of telitacicept versus belimumab in lupus nephritis.
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Efficacy and Safety of CRC01 in Participants With Severe, Refractory Systemic Lupus Erythematosus [Phase 1, Phase 2]
CRC01 is being evaluated in a Phase 1/2 clinical trial for severe refractory systemic lupus erythematosus, including lupus nephritis, with t…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Study to Assess Demographic, Pharmacologic, Biomarker, Clinical Features and Quality of Life (QoL) of Participants With Lupus Nephritis
A completed study by GlaxoSmithKline examining demographic, pharmacologic, biomarker, clinical features, and quality of life in participants…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Study of Ravulizumab in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN) [Phase 2]
A Phase 2 study of ravulizumab in proliferative lupus nephritis and immunoglobulin A nephropathy has been terminated, with results posted in…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Detection of Anti-glomerular Basement Membrane Antibodies (Anti-GBM): a Promising Biomarker for Lupus Nephritis (LN)? [NA]
This update reports on evaluating anti-GBM antibodies as a biomarker for lupus nephritis in a completed trial. The trial status is completed…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: BCMA-CD19 cCAR T for the Treatment of Refractory Lupus [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating BCMA-CD19 cCAR T therapy for refractory systemic lupus erythematosus and lupus nephritis, sponsored by…
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: A Study to Assess Effectiveness and Safety of Efgartigimod in Chinese Patients With Lupus Nephritis (ZL-1103-013) [Phase 2]
A Phase 2 clinical trial evaluating the effectiveness and safety of efgartigimod in Chinese patients with lupus nephritis has been completed…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease [Phase 1]
A Phase 1 safety and efficacy study of CTX112 in adults with refractory autoimmune diseases, including systemic lupus erythematosus and syst…
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: Evaluating the Safety of Myfortic (Mycophenolate Sodium) in Patients With Lupus Nephritis
A completed clinical trial evaluating the safety of Myfortic (mycophenolate sodium) in patients with lupus nephritis.
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: A Study of Zetomipzomib (KZR-616) in Patients With Active Lupus Nephritis (PALIZADE) [Phase 2]
A Phase 2 study of Zetomipzomib (KZR-616) in patients with active lupus nephritis has been terminated, and results have been posted.
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With ISN/RPS 2003 Class III or IV Lupus Nephritis [Phase 3]
This update summarizes results from a Phase 3 study of obinutuzumab in ISN/RPS 2003 Class III or IV lupus nephritis. The trial status is act…
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: Study of ALXN2050 in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN) [Phase 2]
Phase 2 study of ALXN2050 in proliferative lupus nephritis and IgA nephropathy was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Efficacy and Safety of Tacrolimus Versus Mycophenolate in Lupus Nephritis [Phase 3]
A Phase 3 clinical trial comparing tacrolimus with mycophenolate mofetil in lupus nephritis has completed, evaluating efficacy and safety ou…
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: LUPKYNIS Drug-use Results Survey
This ClinicalTrials.gov update describes a drug-use results survey for LUPKYNIS (voclosporin) in lupus nephritis, and the trial is currently…
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Weaning of Immunosuppression in Nephritis of Lupus [Phase 3]
A Phase 3 study evaluating the weaning of immunosuppression in lupus nephritis has completed.
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Obe-cel in Severe, Refractory Systemic Lupus Erythematosus With Active Lupus Nephritis [Phase 2]
Phase 2 trial update for obe-cel in patients with severe, refractory systemic lupus erythematosus and active lupus nephritis; the study is c…
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CLINICAL_TRIALS trial_result · 2025-06-24Clinical Trial Update: A Prospective Observational Registry of Patients Treated With LUPKYNIS® (Voclosporin) in the US
This is a prospective observational registry of lupus nephritis patients treated with LUPKYNIS (voclosporin) in the United States, and the s…
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: A Clinical Study of YTS109 Cell in R/R Systemic Lupus Erythematosus [Phase 1]
A Phase 1 clinical study evaluating YTS109 cells in relapsed/refractory systemic lupus erythematosus, including lupus nephritis and immune t…