Lupus Nephritis
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CLINICAL_TRIALS research · 2024-11-08Clinical Trial Update: Universal CAR-T Cell Therapy for Refractory Lupus Nephritis [EARLY_Phase 1]
An early-phase trial evaluating universal CAR-T cell therapy for refractory lupus nephritis is not yet recruiting.
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE) [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating a fourth-generation CAR-T cell therapy targeting BCMA and CD19 for refractory systemic lupus erythemat…
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CLINICAL_TRIALS research · 2024-10-08Clinical Trial Update: Renal Arterial Resistive Index as a Noninvasive Biomarker of Disease Activity in Lupus Nephritis Patients
This entry reports an ongoing clinical trial investigating whether renal arterial resistive index can serve as a noninvasive biomarker of di…
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CLINICAL_TRIALS research · 2024-09-24Clinical Trial Update: Association Between Neuropathy and Some Autoantibodies in Systemic Lupus Erythematosus (SLE) Patients
The document describes a clinical trial investigating the association between neuropathy and certain autoantibodies in systemic lupus erythe…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Renal Survival in Patients with Lupus Nephritis
Clinical trial update regarding a NOT_YET_RECRUITING study on renal survival in patients with lupus nephritis. The sponsor listed is Assiut …
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CLINICAL_TRIALS research · 2024-07-26Clinical Trial Update: Urinary G3BP as a Novel Biomarker in Lupus Nephritis
This clinical trial update investigates urinary G3BP as a novel biomarker for lupus nephritis and indicates the study is not yet recruiting.
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CLINICAL_TRIALS research · 2024-07-11Clinical Trial Update: Safety and Efficacy of PRG-2311 for Refractory Lupus Nephritis and IgG4-Related Disease [EARLY_Phase 1]
An early-phase clinical trial (Phase 1) is evaluating the safety and potential efficacy of PRG-2311 for refractory lupus nephritis and IgG4-…
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CLINICAL_TRIALS research · 2024-07-11Clinical Trial Update: Safety and Efficacy of PRG-1801 for Refractory Lupus Nephritis and IgG4-Related Disease [EARLY_Phase 1]
Early-phase clinical trial evaluating safety and efficacy of PRG-1801 for lupus nephritis and IgG4-related disease is currently recruiting.
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CLINICAL_TRIALS research · 2024-07-09Clinical Trial Update: Effectiveness of Mycophenolate Mofetil Combined With Tacrolimus for Steroid Tapering in Systemic Lupus Erythematosus [Phase 4]
A Phase 4 clinical trial is evaluating whether adding tacrolimus to mycophenolate mofetil helps taper steroids in systemic lupus erythematos…
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CLINICAL_TRIALS research · 2024-07-09Clinical Trial Update: A Study of Clinical Characteristics ,Risk Factors and Outcome of Lupus Nephritis Among Children With Systemic Lupus Erthromatousus in Sohag Univeristy Hospital
A pediatric study at Sohag University Hospital investigates clinical characteristics, risk factors, and outcomes of lupus nephritis in child…
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: Mesenchymal Stem Cell Transfusion for the Treatment of Refractory Lupus Nephritis [EARLY_Phase 1]
An early Phase 1 clinical trial at Chinese PLA General Hospital to evaluate mesenchymal stem cell transfusion for refractory lupus nephritis…
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CLINICAL_TRIALS research · 2024-05-29Clinical Trial Update: T Regulatory Cells IN LUPUS NEPHRITIS
A clinical trial is investigating T regulatory cells for lupus nephritis, currently not yet recruiting.
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CLINICAL_TRIALS research · 2024-05-09Clinical Trial Update: A Study of QLG1074 Combined With Background Therapy in Subjects With Active Lupus Nephritis [Phase 3]
This update outlines a Phase 3 study of QLG1074 in combination with background therapy for active lupus nephritis. The trial is currently re…
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CLINICAL_TRIALS research · 2021-06-11Clinical Trial Update: A Phase II Study to Evaluate the Efficacy and Safety of SHR-1314 in Lupus Nephritis [Phase 2]
Phase II study investigating the efficacy and safety of SHR-1314 in lupus nephritis.
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CLINICAL_TRIALS research · 2018-03-12Clinical Trial Update: Umbilical Cord Mesenchymal Stem Cell Transplantation for Lupus Nephritis [NA]
A clinical trial evaluating transplantation of umbilical cord-derived mesenchymal stem cells for lupus nephritis; the current trial status i…
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CLINICAL_TRIALS research · 2017-07-02Clinical Trial Update: Retrospective Analysis of Renal Prognosis in Patients With Chronic Kidney Disease
A retrospective analysis examines renal prognosis in patients with chronic kidney disease, highlighting conditions such as diabetic nephropa…
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CLINICAL_TRIALS research · 2017-02-27Clinical Trial Update: Iguratimod as Treatment for Refractory Lupus Nephritis [NA]
This document notes a clinical trial evaluating iguratimod for refractory lupus nephritis, sponsored by RenJi Hospital; phase and status are…
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CLINICAL_TRIALS research · 2016-09-14Clinical Trial Update: Lupus Flares and Histological Renal Activity at the End of the Treatment (LuFla)
Clinical trial update for NCT02313974 (LuFla) on lupus nephritis, reporting lupus flares and histological renal activity at the end of treat…
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CLINICAL_TRIALS research · 2015-05-06Clinical Trial Update: The Mechanisms and Significances of Synergistic Effects of Mycophenolic Acid and LPS on IL-1β Secretion by Mononuclear
A clinical trial update examining the synergistic effects of mycophenolic acid and lipopolysaccharide on IL-1β secretion by mononuclear cell…
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CLINICAL_TRIALS research · 2013-05-29Clinical Trial Update: The Effect of Calcitriol on Progress and Activity of Lupus Nephritis [Phase 2]
Phase 2 clinical trial investigating calcitriol for progression and activity in lupus nephritis associated with systemic lupus erythematosus…
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CLINICAL_TRIALS research · 2012-03-06Clinical Trial Update: Phase 2 Study of Human Umbilical Cord Derived Mesenchymal Stem Cell for the Treatment of Lupus Nephritis [Phase 2]
Phase 2 clinical trial studying human umbilical cord-derived mesenchymal stem cells for lupus nephritis; the current status of the study is …
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CLINICAL_TRIALS research · 2009-03-05Clinical Trial Update: Cyclophosphamide in Lupus Nephritis
An update on a clinical trial evaluating cyclophosphamide for lupus nephritis in systemic lupus erythematosus, sponsored by the University o…
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CLINICAL_TRIALS research · 2008-04-16Clinical Trial Update: Effect of Mesenchymal Stem Cell Transplantation for Lupus Nephritis [Phase 1, Phase 2]
A Phase 1/2 clinical trial is investigating mesenchymal stem cell transplantation as a treatment for lupus nephritis. The current status of …
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CLINICAL_TRIALS research · 2007-12-06Clinical Trial Update: A Pilot Study for the Efficacy and Safety of Tacrolimus in the Treatment of Refractory Lupus Nephritis [Phase 2]
Pilot Phase 2 study evaluating the efficacy and safety of tacrolimus in the treatment of refractory lupus nephritis.