Lupus Nephritis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Phase 3 Study of Anifrolumab in Adult Patients With Active Proliferative Lupus Nephritis [Phase 3]
Phase 3 clinical trial update for Anifrolumab in adults with active proliferative lupus nephritis; the study is currently active but not rec…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating CART19, autologous CD19-directed CAR T cells, for systemic lupus erythematosus and lupus nephritis.…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: A Study of Rapcabtagene Autoleucel in Active, Refractory Systemic Lupus Erythematosus (SLE) or Lupus Nephritis (LN) Patients (AUTOGRAPH - SLE/LN) [Phase 2]
Phase 2 clinical trial update for rapcabtagene autoleucel in active, refractory systemic lupus erythematosus and lupus nephritis, currently …
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: CARTIMMUNE: Study of Patients With Autoimmune Diseases Receiving KYV-101 [Phase 1]
Phase 1 study update for KYV-101 (CARTIMMUNE) evaluating autoimmune diseases including idiopathic inflammatory myopathies, diffuse cutaneous…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101
A long-term follow-up study for participants previously treated with KYV-101; recruitment is ongoing across multiple autoimmune diseases.
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Dapagliflozin in Active Lupus Nephritis [Phase 4]
A Phase 4 clinical trial is evaluating dapagliflozin for active lupus nephritis. The study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: A Multicenter Phase 2a Clinical Study to Evaluate SIM0278 in Subjects With Active Lupus Nephritis [Phase 2]
A multicenter Phase 2a study evaluating SIM0278 in active lupus nephritis is planned, with the trial status listed as not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: C-CAR168 CAR T Cell Therapy for Refractory Autoimmune Disease [Phase 1, Phase 2]
A Clinical Trial Update announcing AbelZeta's C-CAR168 CAR T cell therapy is in Phase 1/Phase 2 studies for refractory lupus nephritis, with…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Study to Assess Efficacy and Safety of HSK39297 Tablets in Patients With LN [Phase 2]
A Phase 2 clinical trial is evaluating the efficacy and safety of HSK39297 tablets in lupus nephritis and is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: UB-VV410 in Subjects With Active Refractory Systemic Lupus Erythematosus or Lupus Nephritis [Phase 1]
Phase 1 study evaluating UB-VV410 in adults with active refractory systemic lupus erythematosus or lupus nephritis; recruitment is currently…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Research Accelerated by You Lupus Registry
This clinical trial registry entry describes the Lupus Registry study sponsored by the Lupus Foundation of America, which is currently recru…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Phase IIa Study for IPG11406 in Patients With Lupus Nephritis [Phase 1, Phase 2]
A Phase 1/2 clinical trial update for IPG11406 in patients with lupus nephritis. The study is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: A Study of CNTY-101 in Participants With Refractory B Cell-mediated Autoimmune Diseases [Phase 1]
Century Therapeutics’ CNTY-101 is being evaluated in a Phase 1 study for refractory B cell–mediated autoimmune diseases, with the trial curr…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: The Relation Between Serum Zinc and Lupus Nephritis
A new clinical trial is investigating the relationship between serum zinc levels and lupus nephritis, and it is currently not recruiting.
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: A Study to Learn More About the Safety and Effects of Felzartamab in Adults With Lupus Nephritis Aged 18 to 75 Years Old [Phase 1]
This document reports a Phase 1 clinical trial evaluating the safety and effects of Felzartamab in adults with lupus nephritis, sponsored by…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: VIBRANT: VIB4920 for Active Lupus Nephritis [Phase 2]
A Phase 2 trial evaluating VIB4920 for active lupus nephritis is currently recruiting, sponsored by the National Institute of Allergy and In…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: AB-101 in Combination With B-Cell Depleting mAb in Patients Who Failed Treatment for Class III or IV Lupus Nephritis or Other Forms of Refractory Systemic Lupus Erythematosus [Phase 1]
This Phase 1 clinical trial update shows AB-101, in combination with a B-cell depleting monoclonal antibody, is being studied in lupus nephr…
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: A Phase II Clinical Study on the Efficacy and Safety of SHR-2173 Injection in the Treatment of Patients With Active Lupus Nephritis [Phase 2]
A Phase II clinical study evaluating the efficacy and safety of SHR-2173 injection for active lupus nephritis, with recruitment currently on…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Induction Therapy for Lupus Nephritis With no Added Oral Steroids: A Trial Comparing Oral Corticosteroids Plus Mycophenolate Mofetil (MMF) Versus Obinutuzumab and MMF [Phase 3]
Phase 3 trial update comparing induction therapy for lupus nephritis with oral corticosteroids plus mycophenolate mofetil (MMF) versus obinu…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Safety and Efficacy of ONT01 in Lupus [EARLY_Phase 1]
ONT01 is in an early Phase 1 trial for lupus nephritis and systemic lupus erythematosus and is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: A Study to Evaluate the Efficacy, Safety, and Tolerability of Human Sialidase Fusion Protein (HLX79) in Combination With Rituximab Injection Versus Placebo in Patients With Active Glomerulonephritis [Phase 2]
Phase 2 trial evaluating HLX79 in combination with Rituximab versus placebo for active glomerulonephritis, including membranous nephropathy …
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Safety and Efficacy of Combination Belimumab and Voclosporin in the Treatment of Proliferative Forms of Lupus Glomerulopathy: Synergy Trial [Phase 4]
A Phase 4 trial evaluating the safety and efficacy of combining belimumab with voclosporin for proliferative lupus nephritis; currently recr…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: A Phase 1 Study of SYNCAR-001 + STK-009 Without Conditioning Chemotherapy (Lymphodepletion) in Subjects With Severe, Refractory Systemic Autoimmune Rheumatic Disease [Phase 1]
Synthekine reports a Phase 1 study of SYNCAR-001 plus STK-009 without lymphodepletion in subjects with severe, refractory systemic autoimmun…
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: KYSA-3: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis [Phase 1, Phase 2]
Clinical trial update for KYSA-3, an anti-CD19 CAR T-cell therapy, in subjects with refractory lupus nephritis (Phase 1/2; active/not recrui…
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: KYSA-1: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis [Phase 1, Phase 2]
KYSA-1, an anti-CD19 CAR T-cell therapy, is being studied in refractory lupus nephritis in Phase 1/2 and is currently not recruiting.