Lupus Nephritis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V [Phase 2]
This clinical trial entry outlines a Phase 2 study to evaluate the efficacy and safety of iptacopan (LNP023) in adults with active lupus nep…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE) [Phase 2]
Phase 2 study Breakfree-SLE is evaluating CC-97540 (BMS-986353 / Zola-cel), a CD19-targeted NEX-T CAR T cell, in participants with active sy…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Lupus Landmark Study: A Prospective Registry and Biorepository
A prospective lupus registry and biorepository is being established to collect clinical data and biospecimens from patients with systemic lu…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders [Phase 1, Phase 2]
Phase I/II trial of AD-PluReceptor plus tafasitamab-cxix with lymphodepleting chemotherapy in autoimmune disorders is currently recruiting, …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Dose Escalation Study With Bispecific Antibodies in Adult Patients With Lupus Nephritis [Phase 1]
Phase 1 dose-escalation study evaluating investigational bispecific antibodies in adults with lupus nephritis. The study is currently recrui…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus [Phase 1, Phase 2]
A Phase 1/2 open-label study evaluating the safety and efficacy of CABA-201 in active systemic lupus erythematosus (including lupus nephriti…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: CHT105 for the Treatment of Refractory Lupus Nephritis [NA]
Clinical trial update for CHT105 evaluating its use in refractory lupus nephritis; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study of KITE-363 in Participants With Refractory Autoimmune Diseases [Phase 1]
Phase 1 study evaluating KITE-363 in participants with refractory autoimmune diseases, currently enrolling by invitation, including systemic…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants [Phase 2]
Phase 2 study to evaluate the efficacy, safety, and pharmacokinetics of obinutuzumab in adolescents with active Class III/IV lupus nephritis…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Anti-alpha-actinin Antibodies and Lupus Nephritis Activity
Assiut University is conducting a clinical trial to evaluate anti-alpha-actinin antibodies for lupus nephritis; the study is not yet recruit…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Study to Assess Real-world Effectiveness of Belimumab for Treatment of Adults With LN
A real-world effectiveness study to evaluate belimumab for adults with lupus nephritis is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: A Research Trial to Assess if Cenerimod is Efficacious and Safe to Treat Active Lupus Nephritis on Top of Regular Treatment [Phase 3]
A Phase 3 clinical trial is recruiting to evaluate the efficacy and safety of Cenerimod in active lupus nephritis on top of standard therapy…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: A Phase 1 Study of HB2198 in Participants With Moderately to Severely Active Systemic Lupus Erythematosus (SLE) [Phase 1]
A Phase 1 study evaluating HB2198 in adults with systemic lupus erythematosus, including lupus nephritis, is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Therapeutic Drug Monitoring of Mycophenolate Mofetil in Lupus Nephritis [NA]
This ClinicalTrials.gov study evaluates therapeutic drug monitoring of mycophenolate mofetil in systemic lupus erythematosus and lupus nephr…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Phase 1 Study of Prulacabtagene Leucel (Prula-cel, Formerly ADI-001) in Autoimmune Disease [Phase 1]
Phase 1 trial update for Prulacabtagene Leucel (Prula-cel) in autoimmune diseases, with enrollment by invitation ongoing across indications …
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Safety, Efficacy and Tolerability of Ianalumab Versus Placebo, Combination With SoC Therapy, in Participants With Active Lupus Nephritis [Phase 3]
A Phase 3 clinical trial update evaluating ianalumab versus placebo (with standard of care) in active lupus nephritis, focusing on safety, e…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study [Phase 2]
A Phase 2 pediatric trial investigating mycophenolate mofetil for lupus nephritis is currently recruiting at Cincinnati Children's Hospital …
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: The Efficacy and Safety of Biologics (Belimumab/ Telitacicept) Induction Therapy in Proliferative Lupus Nephritis Patients for 6 Months Compared With Mycophenolate Mofetil Treatment [Phase 2]
This Phase 2 study is evaluating the efficacy and safety of induction therapy combining belimumab and telitacicept in proliferative lupus ne…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Phase III Extension Study of Efficacy and Safety of Ianalumab With or Without Study Treatment Withdrawal in Participants With Lupus Nephritis (SIRIUS-LN Extension) [Phase 3]
Phase 3 extension study evaluating the efficacy and safety of ianalumab in lupus nephritis, with or without withdrawal of other study treatm…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory Systemic Lupus Erythematosus [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating anti-CD19 CAR-T cell therapy for refractory systemic lupus erythematosus, including lupus nephritis…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1) [Phase 1, Phase 2]
Nkarta, Inc. is conducting a Phase 1/2 study of NKX019 for autoimmune diseases and is currently recruiting. The trial targets lupus nephriti…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: An Exploratory Clinical Study of YTS109 Cell for R/R Autoimmune Diseases [Phase 1]
Exploratory Phase 1 clinical trial evaluating YTS109 Cell for relapsed/refractory autoimmune diseases, including systemic lupus erythematosu…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: CD19-BCMA CART Cell Therapy for Refractory SLE-LN, SSc, and pSS-PAH [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating CD19-BCMA CAR T cell therapy for refractory lupus nephritis, systemic sclerosis, and primary Sjögren's…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: A Clinical Study of YTS109 Cells for the Treatment of R/R Autoimmune Diseases [Phase 1]
Phase 1 trial update on YTS109 cell therapy for relapsed/refractory autoimmune diseases, currently recruiting across multiple indications.
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: A Clinical Study of YTS109 Cell for R/R Autoimmune Diseases [Phase 1]
Phase 1 clinical study of YTS109 cell therapy for refractory autoimmune diseases is currently recruiting. The trial will evaluate safety and…