Lower Respiratory Tract Infection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Utilization and Compliance of Respiratory Syncytial Virus Monoclonal Antibody Therapy
This completed trial update reports how RSV monoclonal antibody therapy was used and how compliant sites were with its administration for RS…
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CLINICAL_TRIALS trial_result · 2017-12-05Clinical Trial Update: Prospective Clinical Evaluation of the FilmArray® Lower Respiratory Tract Infection (LRTI) Panel
This document reports the completed prospective clinical evaluation of the FilmArray LRTI Panel for diagnosing lower respiratory tract infec…
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CLINICAL_TRIALS trial_result · 2017-11-28Clinical Trial Update: Pharmacokinetics, Safety and Efficacy of POL7080 in Patients With Ventilator Associated Pseudomonas Aeruginosa Pneumonia [Phase 2]
Phase 2 study evaluating pharmacokinetics, safety and efficacy of POL7080 in ventilator-associated pneumonia due to Pseudomonas aeruginosa; …
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CLINICAL_TRIALS trial_result · 2017-11-28Clinical Trial Update: Assess a Diagnostic Tool to Distinguish Between Bacterial and Viral Infection
A completed clinical trial assessed a diagnostic tool designed to distinguish bacterial from viral infections in patients with lower respira…
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CLINICAL_TRIALS trial_result · 2017-04-20Clinical Trial Update: Maternal Vitamin D for Acute Respiratory Infections in Infancy [Phase 3]
Phase 3 trial evaluating maternal vitamin D supplementation to prevent acute respiratory infections in infancy; the study has completed.
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CLINICAL_TRIALS research · 2017-04-14Clinical Trial Update: Study Bronchoalveolar Lavage Fluid Driven Pathogenic Diagnosis of Lower Respiratory Tract Infections [NA]
This clinical trial update describes a study evaluating bronchoalveolar lavage fluid-guided pathogenic diagnosis for lower respiratory tract…
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CLINICAL_TRIALS research · 2017-03-03Clinical Trial Update: Impact of Introduction of PHiD-CV for Nunavik Children, Quebec, Canada
This clinical trial update examines the impact of introducing the pneumococcal vaccine PHiD-CV (Synflorix) for Nunavik children. It covers o…
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CLINICAL_TRIALS trial_result · 2017-02-01Clinical Trial Update: Safety, Efficacy and PK/PD of POL7080 in Patients With Exacerbation of Non-cystic Fibrosis Bronchiectasis. [Phase 2]
A Phase 2 trial of POL7080 in exacerbations of non-cystic fibrosis bronchiectasis was terminated; the update notes evaluation of safety, eff…
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CLINICAL_TRIALS research · 2017-01-13Clinical Trial Update: Prospective Study to Characterize Host-pathogen Related Factors in Hospitalized and ED Patients With LRTI and/or Sepsis
A prospective observational study by MeMed Diagnostics completed to characterize host-pathogen factors in hospitalized and ED patients with …
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CLINICAL_TRIALS trial_result · 2016-07-27Clinical Trial Update: Anti-inflammatory Effects of Macrolide Treatment in Influenza Lower Respiratory Tract Infections [Phase 4]
Phase 4 clinical trial investigating anti-inflammatory effects of macrolide treatment in influenza-associated lower respiratory tract infect…
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CLINICAL_TRIALS research · 2016-03-08Clinical Trial Update: Observational, Prospective Clinical Study to Evaluate Biomarkers as Indicators of Acute Bacterial or Viral Infections
Observational, prospective clinical study evaluating biomarkers as indicators of acute bacterial or viral infections.
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CLINICAL_TRIALS trial_result · 2016-02-25Clinical Trial Update: Meropenem Dosage Strategy Based on PPK Model [Phase 4]
Phase 4 clinical trial evaluating a population pharmacokinetic-based dosing strategy for meropenem in lower respiratory tract infections; re…
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CLINICAL_TRIALS research · 2015-10-05Clinical Trial Update: DNA-based Testing in BAL of Lung Transplant Recipients With Suspected Non-viral Lower Respiratory Tract Infection
This clinical trial update covers the use of DNA-based testing on bronchoalveolar lavage from lung transplant recipients with suspected non-…
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FDA label_change · 2015-03-16FDA Approved: AUGMENTIN ES-600 — Supplemental Application (USAntibiotics, LLC)
FDA approved a supplemental application for AUGMENTIN ES-600 by USAntibiotics, LLC, updating the product labeling.
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CLINICAL_TRIALS research · 2014-06-26Clinical Trial Update: The Impact of a Short Intervention During RSV Prophylaxis on Influenza Vaccination Rate. [NA]
This clinical trial update examines whether a short intervention during respiratory syncytial virus prophylaxis affects influenza vaccinatio…
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CLINICAL_TRIALS research · 2014-03-20Clinical Trial Update: Characterize Novel Pathogen- and Host- Related Factors in Hospitalized Patients and Patients on the Emergency Department Presenting With Lower Respiratory Tract Infections and/or Sepsis
This clinical trial entry (NCT02093247) seeks to characterize novel pathogen- and host-related factors in hospitalized and emergency departm…
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FDA approval · 2014-03-05FDA Approved: CIPROFLOXACIN — Original Application (Chartwell RX, LLC)
FDA approved the original application for ciprofloxacin (generic) by Chartwell RX, LLC.
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CLINICAL_TRIALS trial_result · 2014-02-19Clinical Trial Update: Fast Identification of Pathogen in the Setting of Pneumonia Using Multiplex PCR
This completed clinical trial evaluated rapid pathogen identification in pneumonia using multiplex PCR and reports its findings.
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CLINICAL_TRIALS trial_result · 2014-02-04Clinical Trial Update: Effect of Vitamin D Supplementation in Young South African Children Hospitalized With Acute Lower Respiratory Infection [Phase 4]
This Clinical Trial Update reports on a Phase 4 study evaluating whether vitamin D supplementation affects outcomes in young South African c…
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CLINICAL_TRIALS trial_result · 2014-01-21Clinical Trial Update: A Trial to Reduce Pneumonia in Nursing Home Residents [Phase 3]
Phase 3 trial results from a Yale University-sponsored study evaluating an intervention to reduce pneumonia and lower respiratory tract infe…
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CLINICAL_TRIALS research · 2013-10-29Clinical Trial Update: Nutritional Intervention and Respiratory Infections in Older Subjects [NA]
A clinical trial update examining whether a nutritional intervention affects rates of upper and lower respiratory infections in older adults…
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CLINICAL_TRIALS trial_result · 2013-10-16Clinical Trial Update: Effectiveness of Nutritional Supplementation in Preventing Malnutrition in Children With Infection [NA]
Clinical trial update evaluating whether nutritional supplementation can prevent malnutrition in children with infections, including malaria…
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CLINICAL_TRIALS research · 2013-08-13Clinical Trial Update: Smoking Ban and Paediatric Hospital Admissions for Respiratory Tract Infections in England
This document notes the completion of a clinical trial evaluating whether a smoking ban affects pediatric hospital admissions for respirator…
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CLINICAL_TRIALS trial_result · 2013-04-24Clinical Trial Update: RI-001 in Immunosuppressed Respiratory Syncytial Virus (RSV) Infected Patients at Risk of Lower Tract RSV Illness [Phase 2]
A Phase 2 study update reports the results of RI-001 in immunosuppressed patients infected with Respiratory Syncytial Virus at risk for lowe…
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CLINICAL_TRIALS trial_result · 2013-01-10Clinical Trial Update: Fast Identification of Pathogen in the Setting of Hospital-acquired Pneumonia Using Ion Mobility Spectrometry
A completed clinical trial evaluating a rapid pathogen-identification method using ion mobility spectrometry for hospital-acquired pneumonia…