Lower Respiratory Tract Infection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-04-18Clinical Trial Update: Advanced Diagnostics for Enhanced QUality of Antibiotic Prescription in Respiratory Tract Infections in Emergency Rooms [NA]
A completed clinical trial evaluating advanced diagnostics aimed at improving antibiotic prescribing for community-acquired acute lower resp…
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CLINICAL_TRIALS research · 2025-04-15Clinical Trial Update: The Effect of Vitamin E Supplementation on Hospital Stay Duration in Non-cyanotic Heart Disease Children With Lower Respiratory Tract Infections [Phase 4]
Phase 4 clinical trial evaluating whether vitamin E supplementation affects hospital stay duration in children with non-cyanotic congenital …
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CLINICAL_TRIALS trial_result · 2025-04-08Clinical Trial Update: Flublok v. Standard Dose Vaccine Effectiveness Among Kaiser Permanente Northern California Adults 18-64 Years
A completed trial comparing Flublok recombinant influenza vaccine with a standard-dose influenza vaccine in adults aged 18-64, with results …
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: Effect of Pediatric Lung Ultrasound on Antibiotic Prescriptions in Hospitalized Children and Adolescents With Lower Respiratory Tract Infections. A Randomized Controlled Trial. [NA]
A randomized controlled trial evaluating whether pediatric lung ultrasound can influence antibiotic prescribing for hospitalized children an…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Correlation Analysis of Xpert Carba-R Detection of Non-colonized CRE in BALF and Rectal Swabs From Patients With LRTI
This update reports enrollment status for a study evaluating Xpert Carba-R detection of non-colonized carbapenem-resistant Enterobacteriacea…
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CLINICAL_TRIALS trial_result · 2025-03-04Clinical Trial Update: Early Versus Late BCG Vaccination in HIV-1 Exposed Infants in Uganda in Uganda [Phase 3]
This update reports on a Phase 3 trial comparing early versus late Bacillus Calmette-Guérin vaccination in HIV-exposed infants in Uganda, wh…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Host Blood RNA Signatures for Diagnosis of TB
The University of Stellenbosch-sponsored trial evaluating host blood RNA signatures for diagnosing tuberculosis is currently active but not …
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CLINICAL_TRIALS trial_result · 2024-11-29Clinical Trial Update: The Effect of Focused Lung Ultrasonography on Antibiotic Prescribing in General Practice [NA]
A completed clinical trial from Aalborg University assessing whether focused lung ultrasonography in general practice influences antibiotic …
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CLINICAL_TRIALS other · 2024-11-20Clinical Trial Update: Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study [Phase 3]
Phase 3 randomized trial of DAS181 for lower respiratory tract Parainfluenza infection in immunocompromised subjects, with a sub-study for C…
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: A Study to Learn About the Effects of Sisunatovir in Infants With Respiratory Syncytial Virus Lower Respiratory Tract Infection. [Phase 2]
Pfizer's Phase 2 trial of sisunatovir in infants with respiratory syncytial virus lower respiratory tract infection has been terminated, wit…
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CLINICAL_TRIALS research · 2024-10-16Clinical Trial Update: Safe, Effective and Cost-Effective Oxygen Saturation Targets for Children and Adolescents With Respiratory Distress: a Randomized Controlled Trial [NA]
An update on a randomized controlled trial examining safe, effective, and cost-effective oxygen saturation targets in pediatric patients wit…
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CLINICAL_TRIALS research · 2024-09-04Clinical Trial Update: Recurrent Pneumonia in Children
A pediatric clinical trial sponsored by Assiut University is investigating pneumonia and lower respiratory tract infections, with the study …
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FDA approval · 2024-08-22FDA Approved: AMPICILLIN AND SULBACTAM — Supplemental Application (Eugia US LLC)
FDA granted supplemental approval for Ampicillin and Sulbactam (AMPICILLIN AND SULBACTAM) submitted by Eugia US LLC.
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CLINICAL_TRIALS research · 2024-08-22Clinical Trial Update: Protecting Preterm Infants From Respiratory Tract Infections and Wheeze by Using Bacterial Lysates. [Phase 3]
Phase 3 clinical trial evaluating bacterial lysates to protect preterm infants from lower respiratory tract infections and wheeze; recruitme…
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CLINICAL_TRIALS trial_result · 2024-05-30Clinical Trial Update: Copeptin: Disease Severity Indicator [NA]
A completed clinical trial evaluated copeptin as a biomarker for disease severity in patients with lower respiratory tract infections, inclu…
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: CRP and Lung Ultrasound in Respiratory Evaluation
A clinical trial evaluating the use of C-reactive protein measurement and lung ultrasound to evaluate respiratory conditions in a primary ca…
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FDA approval · 2024-04-25FDA Approved: AMOXICILLIN AND CLAVULANATE POTASSIUM — Supplemental Application (NorthStar Rx LLC)
FDA approved a Supplemental Application for Amoxicillin and clavulanate potassium by NorthStar Rx LLC, indicating a modification to an exist…
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CLINICAL_TRIALS trial_result · 2022-06-02Clinical Trial Update: Wood Stove Interventions and Child Respiratory Health [NA]
Completed clinical trial assessing wood stove interventions and child respiratory health with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2021-08-24Clinical Trial Update: Placebo-Controlled Trial of Antibiotic Therapy in Adults With Suspect Lower Respiratory Tract Infection (LRTI) and a Procalcitonin Level [NA]
A placebo-controlled trial evaluating antibiotic therapy in adults with suspect lower respiratory tract infection and elevated procalcitonin…
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FDA approval · 2021-04-16FDA Approved: AZACTAM — Supplemental Application (E.R. Squibb & Sons, L.L.C.)
FDA approved a supplemental application for AZACTAM (aztreonam) from E.R. Squibb & Sons, L.L.C. The approval updates the product labeling fo…
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CLINICAL_TRIALS trial_result · 2021-02-04Clinical Trial Update: Evaluation of Moderate to Severe Influenza Outcomes in Children
A completed clinical trial evaluating moderate to severe influenza outcomes in children with results posted in 2021, investigating influenza…
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CLINICAL_TRIALS trial_result · 2020-03-25Clinical Trial Update: Using Pneumococcal Vaccines in Combination for Maximum Protection From Ear and Lung Infections in First 3 Years of Life [Phase 4]
A Phase 4 clinical trial investigated using pneumococcal vaccines in combination to maximize protection against ear and lung infections in t…
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CLINICAL_TRIALS trial_result · 2019-08-28Clinical Trial Update: Preliminary Study of Dornase Alfa to Treat Chest Infections Post Lung Transplant. [Phase 2]
Preliminary Phase 2 study evaluating Dornase Alfa for chest infections after lung transplant completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-01-15Clinical Trial Update: Procalcitonin Antibiotic Consensus Trial (ProACT) [NA]
Completed clinical trial evaluating procalcitonin-guided antibiotic therapy for lower respiratory tract infection; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2018-06-06Clinical Trial Update: Oseltamivir Randomised Controlled Efficacy Trial [Phase 3]
Phase 3 randomized controlled trial evaluating the efficacy of oseltamivir for influenza and related respiratory infections; the study has c…