Low-grade Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: DAY101 In Gliomas and Other Tumors [Phase 1]
A Phase 1 trial update for DAY101 in gliomas and other tumors, with the Low-grade glioma arm reported as completed.
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Phase 1/2 Study of Mirdametinib + Vinblastine for Newly Diagnosed/Previously Untreated PLGG + Activation of MAPK [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the combination of mirdametinib and vinblastine for newly diagnosed pediatric low-grade glioma with…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS Trial [Phase 2]
A Phase 2 trial (PODS) is evaluating post-operative dosing of dexamethasone in brain tumor patients after craniotomy; the study is currently…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Niraparib In Recurrent IDH 1/2 Gliomas [EARLY_Phase 1]
An early-phase 1 trial update evaluating niraparib in recurrent IDH1/2-mutant gliomas, including low-grade and malignant gliomas.
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma [Phase 1, Phase 2]
Clinical trial update for SJ901 evaluating mirdametinib in children, adolescents, and young adults with low-grade glioma; the Phase 1/Phase …
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration [Phase 1, Phase 2]
Status update for a Phase 1/2 trial evaluating dabrafenib, trametinib, and hydroxychloroquine in patients with recurrent low-grade or high-g…
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CLINICAL_TRIALS withdrawal · 2026-01-28Clinical Trial Update: Repeatability of Magnetic Resonance Imaging in Patients With IDH1 Mutant Glioma on Ivosidenib [NA]
This clinical trial update indicates that the study evaluating MRI repeatability in IDH1-mutant glioma patients treated with Ivosidenib has …
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Intensity-Modulated Stereotactic Radiation Therapy in Treating Patients With Grade II-IV Glioma [NA]
Ongoing clinical trial evaluating intensity-modulated stereotactic radiotherapy for patients with grade II–IV gliomas, including glioblastom…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: A Living Tissue Bank of Patient-Derived Organoids From Glioma Tumors
The study aims to establish a living tissue bank of patient-derived glioma organoids. Recruitment is ongoing for patients with low-grade gli…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Rehabilitation and Longitudinal Follow-up of Cognition in Adult Lower Grade Gliomas [NA]
This entry reports that the University of California, San Francisco is recruiting for a clinical trial studying rehabilitation and longitudi…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma [Phase 3]
This is a Phase 3 trial comparing radiation therapy with concomitant and adjuvant temozolomide versus radiation therapy with adjuvant PCV ch…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: A Study Using Brain Stimulation and Behavioral Therapy to Increase Extent of Resection in Low-Grade Gliomas [NA]
A ClinicalTrials.gov study is investigating brain stimulation combined with behavioral therapy to increase the extent of surgical resection …
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Phase 3 Study of Vorasidenib (S095032/AG-881) in Asian Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 orIDH2 Mutation [Phase 3]
A Phase 3 trial evaluating vorasidenib for Asian participants with residual or recurrent grade 2 IDH-mutant glioma is currently active but n…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: A Vaccine Trial for Low Grade Gliomas [Phase 2]
Phase 2 vaccine trial for low-grade glioma is currently recruiting, per ClinicalTrials.gov.
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Fluorescence Spectroscopy Guided Surgery [Phase 1]
Phase 1 clinical trial evaluating fluorescence spectroscopy guided surgery for patients with gliomas. The study including low-grade glioma a…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma [Phase 1]
Phase 1 study of TRIAPINE in combination with temozolomide for recurrent glioblastoma and recurrent gliomas; currently listed as active but …
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Developing Fast Pediatric Imaging [NA]
A clinical trial update from Boston Children's Hospital describes developing a fast imaging method for pediatric low-grade gliomas, currentl…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Proton Radiation Therapy for Gliomas [NA]
This trial update reports that the proton radiation therapy study for gliomas at Massachusetts General Hospital remains active but not recru…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG [EARLY_Phase 1]
This is an early-phase (Phase 1) clinical trial evaluating 18F-Fluciclovine PET-MRI imaging in low-grade glioma, currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: Nivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator Phenotype [Phase 2]
A Phase 2 trial of nivolumab in IDH-mutant gliomas, with and without hypermutator phenotype, has results posted on ClinicalTrials.gov.
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer) [NA]
The HOBSCOTCH-CA trial, a home-based self-management and cognitive training program for brain cancer patients, is currently recruiting.
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Anti-GARP Chimeric Antigen Receptor T Cell Therapy for the Treatment of Recurrent Grade III or IV Gliomas [Phase 1]
Phase 1 trial update for an Anti-GARP CAR-T cell therapy targeting recurrent Grade 2-4 gliomas (including glioblastoma), currently recruitin…
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CLINICAL_TRIALS trial_result · 2025-10-07Clinical Trial Update: Study of MEK162 for Children With Low-Grade Gliomas [Phase 1, Phase 2]
Phase 1/2 trial of MEK162 for children with low-grade gliomas has completed, with results posted in 2025.
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: Measure of the Potential Evoked by Electric Stimulation [NA]
A clinical trial assessing evoked potential responses from electric stimulation in patients with brain low-grade glioma; recruitment is ongo…
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CLINICAL_TRIALS other · 2025-09-08Clinical Trial Update: Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma [Phase 3]
This Phase 3 trial assesses whether adding temozolomide to radiation therapy improves outcomes for patients with low-grade glioma and is cur…