Low Cardiac Output Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Landiolol in Mitral Valve Surgery [Phase 4]
Phase 4 trial of landiolol in patients undergoing mitral valve surgery is currently recruiting for conditions including heart failure and lo…
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: Can Perfusion Index and Cerebral Oxygen Saturation Trends Predict Low Cardiac Output in Pediatric Cardiovascular Surgeries
This clinical trial investigates whether Perfusion Index and cerebral NIRS trends can predict Low Cardiac Output Syndrome in pediatric cardi…
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CLINICAL_TRIALS trial_result · 2024-04-18Clinical Trial Update: Nitric Oxide During Bypass for Arterial Switch Operation [Phase 3]
Phase 3 trial evaluating nitric oxide during bypass in arterial switch operation has completed.
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CLINICAL_TRIALS trial_result · 2021-01-20Clinical Trial Update: Autologous Umbilical Cord Blood Treatment of Neonate With CHD [Phase 1, Phase 2]
Phase 1/2 clinical trial update investigating autologous umbilical cord blood treatment for neonates with congenital heart disease and relat…
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CLINICAL_TRIALS trial_result · 2021-01-06Clinical Trial Update: Exogenous Ketones for Acutely Decompensated HEart Failure [Phase 3]
Phase 3 clinical trial evaluating exogenous ketones for acutely decompensated heart failure with low cardiac output; status and results are …
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CLINICAL_TRIALS trial_result · 2020-07-24Clinical Trial Update: Spanish Randomized Clinical Trial to Compare Levosimendan Versus Placebo in Postoperative Cardiac Surgery (SPARTANS) [Phase 2, Phase 3]
Clinical trial update comparing levosimendan to placebo in postoperative cardiac surgery patients (SPARTANS) across Phase 2/3; current statu…
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CLINICAL_TRIALS trial_result · 2020-06-30Clinical Trial Update: Milrinone Versus Dobutamine in Critically Ill Patients [Phase 4]
Phase 4 trial comparing milrinone to dobutamine in critically ill patients with low cardiac output syndrome or cardiogenic shock has complet…
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CLINICAL_TRIALS trial_result · 2019-01-30Clinical Trial Update: Prophylactic Use of Milrinone After Congenital Heart Surgery in Infants [Phase 3]
This is a Phase 3 clinical trial update evaluating prophylactic milrinone to prevent low cardiac output syndrome after congenital heart surg…
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: Validation of Automated Cardiac Output Measurement
This clinical trial update reports the completion of validation testing for an automated cardiac output measurement method, evaluated in pat…
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CLINICAL_TRIALS trial_result · 2018-05-22Clinical Trial Update: Levosimendan in Patients With Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery On Cardiopulmonary Bypass [Phase 3]
Phase 3 trial evaluating levosimendan in patients with left ventricular systolic dysfunction undergoing cardiac surgery on cardiopulmonary b…
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CLINICAL_TRIALS trial_result · 2016-11-23Clinical Trial Update: Peak Systolic Global Longitudinal Strain and Low Cardiac Output Syndrome After Cardiac Surgery
A completed clinical trial update examining the relationship between peak systolic global longitudinal strain and the incidence of low cardi…
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CLINICAL_TRIALS trial_result · 2016-07-22Clinical Trial Update: Levosimendan in High Risk Patients Undergoing Cardiac Surgery [Phase 4]
A Phase 4 trial evaluating levosimendan in high-risk patients undergoing cardiac surgery for Low Cardiac Output Syndrome has been completed.
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CLINICAL_TRIALS trial_result · 2016-05-26Clinical Trial Update: Corticosteroids in Postoperative Critically Ill Neonates With Low Cardiac Output Syndrome With Congenital Heart Disease [Phase 2]
A Phase 2 clinical trial update assesses the effects of corticosteroids in postoperative critically ill neonates with low cardiac output syn…
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CLINICAL_TRIALS trial_result · 2012-06-26Clinical Trial Update: Levosimendan Administration in Neonates With Transposition of the Great Arteries [Phase 2]
Phase 2 trial evaluating levosimendan for neonates with transposition of the great arteries, focusing on managing low cardiac output syndrom…
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CLINICAL_TRIALS trial_result · 2012-04-12Clinical Trial Update: Two Inodilators Postsurgery in Neonates [Phase 1, Phase 2]
This clinical trial evaluated two inodilators given after surgery in neonates with Low Cardiac Output Syndrome. The Phase 1/2 study has comp…
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CLINICAL_TRIALS research · 2010-07-07Clinical Trial Update: Hemodynamic Evaluation of Preload Responsiveness in Children by Using PiCCO
A pediatric hemodynamic study using PiCCO to evaluate preload responsiveness in children with shock and sepsis, including related conditions…
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CLINICAL_TRIALS trial_result · 2010-05-20Clinical Trial Update: Metabolic Support With Perhexiline to Protect Myocardium Undergoing Coronary Artery Surgery [Phase 2, Phase 3]
Phase 2/3 trial evaluating metabolic support with perhexiline to protect the myocardium during coronary artery surgery has completed.
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CLINICAL_TRIALS trial_result · 2010-01-26Clinical Trial Update: Levosimendan in Congenital Cardiac Surgery [NA]
A completed clinical trial evaluating the use of levosimendan in congenital heart surgery for congenital heart defects and low cardiac outpu…
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CLINICAL_TRIALS trial_result · 2009-11-25Clinical Trial Update: How Much Cardiac Output is Enough?
A clinical trial sponsored by Klinikum Ludwigshafen evaluating the amount of cardiac output sufficient for patients with Low Cardiac Output …
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CLINICAL_TRIALS research · 2007-10-25Clinical Trial Update: Prophylactic Use of Levosimendan Versus Milrinone in Open Heart Surgery in Infants [Phase 2]
Phase 2 clinical trial assessing the prophylactic use of Levosimendan versus Milrinone to prevent low cardiac output syndrome in infants und…
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CLINICAL_TRIALS trial_result · 2007-09-14Clinical Trial Update: Efficacy, Safety of Hypertonic Lactate Soln. as Fluid Resuscitation Compared With Ringer's Lactate in Post-CABG Pats [Phase 3]
Phase 3 clinical trial comparing hypertonic lactate solution to Lactated Ringer's in post-CABG patients with low cardiac output; the study h…