Or Metastatic Solid Tumors
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CLINICAL_TRIALS trial_result · 2026-08-13Clinical Trial Results: A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants With Advanced Unresectable or Metastatic Solid Tumors [Phase 1, Phase 2]
Phase 1/2 trial evaluating NC410 plus pembrolizumab in advanced/metastatic solid tumors with various MSI statuses; terminated with posted re…
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CLINICAL_TRIALS trial_result · 2026-07-15Clinical Trial Results: A Study of MK-6598 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK-6598-001) [Phase 1]
Phase 1 study evaluating MK-6598 as monotherapy and with pembrolizumab in advanced solid tumors; results completed and posted.
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: NP-G2-044 as Monotherapy and Combination Therapy in Patients With Advanced or Metastatic Solid Tumor Malignancies [Phase 1, Phase 2]
Clinical trial update for NP-G2-044 testing as a standalone and in combination in patients with advanced or metastatic solid tumors, current…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: SCALp Cooling for pReventing aLopecia With nEw anTibody-drug Conjugates [Phase 2]
A Phase 2 clinical trial update describes a scalp cooling approach to prevent alopecia in patients receiving new antibody-drug conjugates fo…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: A Study of YL202 in Patients With Advanced Solid Tumors [Phase 2]
A Phase 2 trial of YL202 in patients with advanced solid tumors is currently recruiting, including non-small cell lung cancer, colorectal ca…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: A Dose-Escalation Study of SPYK04 in Patients With Locally Advanced or Metastatic Solid Tumors (With Expansion). [Phase 1]
A Phase 1 dose-escalation trial of SPYK04 in locally advanced or metastatic solid tumors is ongoing with expansion cohorts; the study is cur…
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CLINICAL_TRIALS trial_result · 2025-05-25Clinical Trial Update: Study to Determine the Safety, Tolerability, Pharmacokinetics and Recommended Phase 2 Dose (RP2D) of Livmoniplimab (ABBV-151) as a Single Agent and in Combination With Budigalimab (ABBV-181) in Participants With Locally Advanced or Metastatic Solid Tumors [Phase 1]
This Phase 1 trial update outlines safety, tolerability, pharmacokinetics and the recommended Phase 2 dose for livmoniplimab alone and in co…
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients with Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies [Phase 1, Phase 2]
An ongoing Phase 1/2 clinical trial evaluating AP203 in patients with locally advanced or metastatic solid tumors, including non-small cell …
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Assessment of Safety and Preliminary Clinical Efficacy with BAT6005 in Advanced Malignant Solid Tumors [Phase 1]
This Phase 1 study assesses the safety, tolerability, pharmacokinetics, and preliminary efficacy of BAT6005 in patients with locally advance…
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CLINICAL_TRIALS trial_result · 2024-03-08Clinical Trial Update: A Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
A safety and tolerability study of NC318 in advanced or metastatic solid tumors completed Phase 1/2 with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2023-08-08Clinical Trial Update: HLX301 (TIGIT×PDL1 Bispecific) in Patients With Locally Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
Clinical trial update for HLX301, a TIGIT×PDL1 bispecific, in locally advanced or metastatic solid tumors and non-small cell lung cancer acr…
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CLINICAL_TRIALS trial_result · 2022-09-08Clinical Trial Update: A Study of MRG004A in Patients With Tissue Factor Positive Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
Phase 1/2 study of MRG004A in patients with tissue factor–positive advanced or metastatic solid tumors (sponsor: Shanghai Miracogen).
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CLINICAL_TRIALS trial_result · 2018-08-07Clinical Trial Update: A Combination Therapy Study of MK-2206 and AZD6244 in Participants With Advanced Solid Tumors (MK-2206-010) [Phase 1]
Phase 1 trial evaluating MK-2206 in combination with AZD6244 in adults with locally advanced or metastatic solid tumors; study completed wit…
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CLINICAL_TRIALS trial_result · 2017-07-26Clinical Trial Update: A Phase I/II Clinical Trial of Vidaza With Abraxane in Patients With Advanced/Metastatic Solid Tumors and Breast Cancer [Phase 1, Phase 2]
A Phase I/II study evaluating azacitidine (Vidaza) in combination with nab-paclitaxel (Abraxane) in patients with advanced or metastatic sol…
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CLINICAL_TRIALS trial_result · 2015-06-29Clinical Trial Update: A Study of Pharmacokinetic Drug Interaction Study of the Hedgehog Pathway Inhibitor GDC-0449 in Combination With Rosiglitazone or Combined Oral Contraceptive in Patients With Locally Advanced or Metastatic Solid Tumors That Are Refractory to Standard Therapy or for Whom No Standard Therapy Exists [Phase 1]
Phase 1 pharmacokinetic interaction study of the Hedgehog pathway inhibitor GDC-0449 with rosiglitazone or with a combined oral contraceptiv…