Liver Transplantation
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Evaluation of Preimplantation Portal Vein and Hepatic Artery Flushing With Tacrolimus [NA]
A completed clinical trial evaluated tacrolimus flushing for use during liver transplantation to mitigate ischemia-reperfusion injury and ea…
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CLINICAL_TRIALS research · 2017-02-07Clinical Trial Update: Remote Ischemic Preconditioning in Liver Transplantation [NA]
A clinical trial update about remote ischemic preconditioning in liver transplantation, sponsored by Mansoura University, with the current s…
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CLINICAL_TRIALS trial_result · 2016-12-21Clinical Trial Update: Conversion From Sirolimus to Everolimus in the Maintenance Treatment of Liver Transplant Recipients
This completed trial evaluated switching liver transplant recipients from sirolimus to everolimus as maintenance immunosuppression.
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CLINICAL_TRIALS trial_result · 2016-11-18Clinical Trial Update: Conversion Trial From Mycophenolate Mofetil (MMF) to Enteric-coated Mycophenolate Sodium (EC-MPS) in Stable Transplanted Patients Suffering From Gastrointestinal (GI) Adverse Events While on Mycophenolate Mofetil Therapy (MMF) Therapy [Phase 4]
Phase 4 trial exploring switching stable transplant recipients from mycophenolate mofetil to enteric-coated mycophenolate sodium due to gast…
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CLINICAL_TRIALS trial_result · 2016-11-07Clinical Trial Update: Conversion of CellCept to Myfortic: A Prospective Study in Liver Transplant Recipients [NA]
This prospective study in liver transplant recipients examines converting immunosuppression from CellCept (mycophenolate mofetil) to Myforti…
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CLINICAL_TRIALS trial_result · 2016-10-12Clinical Trial Update: Determining Equivalence Dose for Oral Versus Sublingual Administration of Tacrolimus in Hepatic Receptors [NA]
A completed clinical trial evaluated whether oral and sublingual tacrolimus dosing provide equivalent exposure. The study focused on patient…
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CLINICAL_TRIALS trial_result · 2016-09-15Clinical Trial Update: Zoledronic Acid Versus Alendronate for Prevention of Bone Loss After Organ Transplantation [Phase 2, Phase 3]
A Phase 2/3 trial comparing zoledronic acid to alendronate for prevention of bone loss after organ transplantation has completed with result…
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CLINICAL_TRIALS trial_result · 2016-07-01Clinical Trial Update: Improving Medication-taking After Liver Transplant [Phase 1]
Phase 1 trial update from Icahn School of Medicine at Mount Sinai evaluating strategies to improve tacrolimus adherence after liver transpla…
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CLINICAL_TRIALS trial_result · 2016-05-12Clinical Trial Update: Cytokine Kinetics Test to Assess the Presence or Absence of Tolerance in Organ Transplant
This clinical trial update notes termination of the study evaluating a cytokine kinetics test to assess tolerance in kidney and liver transp…
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CLINICAL_TRIALS trial_result · 2016-04-12Clinical Trial Update: Safety, Tolerability and Pharmacokinetics of Oral CellCept (Mycophenolate Mofetil) in Pediatric Liver Transplant Recipients on Concomitant Treatment With Cyclosporine and Corticosteroids [Phase 2]
Phase 2 study assessing safety, tolerability, and pharmacokinetics of oral mycophenolate mofetil (CellCept) in pediatric liver transplant re…
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CLINICAL_TRIALS trial_result · 2016-03-15Clinical Trial Update: Study to Ascertain if Prolonged Release Tacrolimus (FK506E - MR4) is Safe and Effective When Used in the Long Term and in Combination With Other Immunosuppressive Drugs in Patients Who Have Received a Transplant [Phase 3]
Phase 3 trial evaluating long-term safety and efficacy of prolonged-release tacrolimus (FK506E-MR4) in transplant recipients when used with …
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CLINICAL_TRIALS research · 2016-03-14Clinical Trial Update: The Influence of ABCB1、CYP3A4、CYP3A5、POR Genetic Polymorphism and Other Factors on Tacrolimus Blood Concentration
This clinical trial update examines how genetic polymorphisms in ABCB1, CYP3A4, CYP3A5, POR and other factors influence tacrolimus blood con…
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CLINICAL_TRIALS trial_result · 2016-02-24Clinical Trial Update: A Study to Compare the Efficacy and Safety of FK506MR vs Prograf® in Patients Undergoing Liver Transplantation [Phase 3]
A Phase 3 trial comparing the efficacy and safety of FK506MR (tacrolimus modified-release) versus Prograf (tacrolimus) in liver transplant p…
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CLINICAL_TRIALS trial_result · 2016-02-24Clinical Trial Update: A Study to Evaluate and Compare the Efficacy and Safety of FK506MR vs Prograf® in Stable Liver Transplantation Patients [Phase 3]
A Phase 3 trial comparing FK506MR with Prograf in stable liver transplant patients has completed.
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CLINICAL_TRIALS trial_result · 2016-01-29Clinical Trial Update: A Study to Compare Safety and Efficacy of Prograf + Myfortic and Advagraf + Myfortic in Liver Transplantation Patients [Phase 4]
A Phase 4 study comparing Tacrolimus regimens Prograf plus Mycophenolate mofetil versus Advagraf plus Mycophenolate mofetil in liver transpl…
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CLINICAL_TRIALS trial_result · 2015-12-29Clinical Trial Update: Single Center Pilot Study of Corticosteroid Discontinuation in Liver Transplant Recipients [Phase 4]
A single-center Phase 4 pilot study evaluated whether liver transplant recipients could safely discontinue corticosteroids.
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CLINICAL_TRIALS trial_result · 2015-12-17Clinical Trial Update: Cefepime Pharmacokinetics in Liver Transplant Recipients in an Intensive Care Unit
This clinical trial update reports cefepime pharmacokinetics in liver transplant recipients in an intensive care unit, reflecting dosing con…
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FDA approval · 2015-12-15FDA Approved: TACROLIMUS — Supplemental Application (Mylan Pharmaceuticals Inc.)
The FDA approved a supplemental application for tacrolimus submitted by Mylan Pharmaceuticals Inc.
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CLINICAL_TRIALS research · 2015-11-24Clinical Trial Update: Clinical Trial of Hydrogen-Rich Celsior Solution Applied in Aging DBD Liver/Kidney Transplantation [Phase 3]
An ongoing Phase 3 clinical trial evaluating hydrogen-rich Celsior solution as a preservation method in aging donation-after-brain-death liv…
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FDA approval · 2015-11-13FDA Approved: MYCOPHENOLATE MOFETIL — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
The FDA approved a supplemental application for mycophenolate mofetil submitted by Teva Pharmaceuticals USA, Inc., updating the drug's label…
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FDA approval · 2015-11-13FDA Approved: MYCOPHENOLATE MOFETIL — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
The FDA approved a supplemental application for a generic version of mycophenolate mofetil from Hikma Pharmaceuticals USA Inc. The drug is u…
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FDA label_change · 2015-10-30FDA Approved: MYCOPHENOLATE MOFETIL — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA supplemental application for mycophenolate mofetil filed by Hikma Pharmaceuticals USA Inc. to update the product labeling.
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FDA approval · 2015-09-28FDA Approved: TACROLIMUS — Supplemental Application (Accord Healthcare Inc.)
FDA approved a supplemental application for tacrolimus by Accord Healthcare Inc., expanding the availability of a generic tacrolimus product…
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CLINICAL_TRIALS trial_result · 2015-09-09Clinical Trial Update: Propofol Versus Dexmedetomidine for Prevention of Sevoflurane Agitation in Recipients of Living Donor Liver Transplantation [NA]
This clinical trial update compares propofol versus dexmedetomidine for preventing sevoflurane-related agitation in recipients of living-don…
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CLINICAL_TRIALS trial_result · 2015-08-28Clinical Trial Update: Pharmacokinetics of LCP-Tacro in Stable Liver Transplant Patients [Phase 2]
Phase 2 pharmacokinetic data for LCP-Tacro were evaluated in stable liver transplant patients. The study was sponsored by Veloxis Pharmaceut…