Liver Transplantation
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-02-28Clinical Trial Update: REnal Function in Liver Transplantation: Everolimus With Calcineurin Inhibitor (CNI)-Sparing sTrategy [Phase 3]
Phase 3 clinical trial evaluating everolimus with a calcineurin inhibitor–sparing strategy on renal function after liver transplantation; co…
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FDA approval · 2019-02-12FDA Approved: MYCOPHENOLATE MOFETIL — Original Application (VistaPharm, LLC)
FDA approves VistaPharm, LLC's generic mycophenolate mofetil for prophylaxis of organ transplant rejection. This Original Application (ANDA …
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FDA approval · 2019-01-31FDA Approved: TACROLIMUS — Original Application (Accord Healthcare Inc.)
The FDA approves Accord Healthcare Inc.'s Original Application for tacrolimus (generic tacrolimus) for prevention of organ transplant reject…
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CLINICAL_TRIALS research · 2019-01-28Clinical Trial Update: Immunosuppressive Therapy Optimization: Development of a Population Pharmacokinetic-pharmacodynamic (PK-PD) Model in Liver Transplantation
A completed study reports development of a population pharmacokinetic-pharmacodynamic model to optimize immunosuppressive therapy in liver t…
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FDA approval · 2018-11-29FDA Approved: ASTAGRAF XL — Supplemental Application (Astellas Pharma US, Inc.)
The FDA approved a supplemental application for ASTAGRAF XL (tacrolimus extended-release capsules) from Astellas Pharma US, Inc., expanding/…
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CLINICAL_TRIALS trial_result · 2018-11-13Clinical Trial Update: Efficacy and Safety of Everolimus in Liver Transplant Recipients of Living Donor Liver Transplants [Phase 3]
Phase 3 trial evaluating efficacy and safety of everolimus in living donor liver transplant recipients completed with posted results.
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CLINICAL_TRIALS trial_result · 2018-10-09Clinical Trial Update: Low Dose Thymoglobulin to Protect Kidney Function After Liver Transplant [NA]
A completed clinical trial evaluating low-dose thymoglobulin to protect kidney function after liver transplantation; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-08-28Clinical Trial Update: Enhancing Donated After Cardiac Death (DCD) Utilization With Thrombolytic Therapy [NA]
Trial assessing thrombolytic therapy to enhance donated after cardiac death (DCD) liver and kidney transplants; study completed with results…
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CLINICAL_TRIALS trial_result · 2018-08-17Clinical Trial Update: Safety Study of Multipotent Progenitor Cells for Immunomodulation Therapy After Liver Transplantation [Phase 1]
Phase 1 safety study of multipotent progenitor cells for immunomodulation after liver transplantation was terminated with posted results.
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CLINICAL_TRIALS trial_result · 2018-07-23Clinical Trial Update: Validity of Mini Fluid Challenge Post Liver Transplantation [NA]
A completed clinical trial evaluating the validity of using a mini fluid challenge to guide fluid management after liver transplantation.
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FDA approval · 2018-05-24FDA Approved: PROGRAF — Supplemental Application (Astellas Pharma US, Inc.)
FDA approved a supplemental application for Prograf (tacrolimus) from Astellas Pharma US, Inc. to update its labeling and indications.
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CLINICAL_TRIALS research · 2018-04-11Clinical Trial Update: Thromboelastometry as a Predictor of Thrombotic Complications During Pediatric Recipient Liver Transplantation
Clinical trial update examining whether thromboelastometry can predict thrombotic complications in pediatric liver transplant recipients.
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CLINICAL_TRIALS trial_result · 2018-02-06Clinical Trial Update: To Evaluate the Efficacy and Safety of ADVAGRAF® After Treatment With a Tacrolimus in New Liver Transplant Recipients [Phase 4]
Phase 4 trial evaluating the efficacy and safety of ADVAGRAF after treatment with tacrolimus in new liver transplant recipients has complete…
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FDA approval · 2017-12-18FDA Approved: CELLCEPT — Supplemental Application (Genentech, Inc.)
FDA approved a supplemental application for CELLCEPT (MYCOPHENOLATE MOFETIL) submitted by Genentech, Inc.
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CLINICAL_TRIALS trial_result · 2017-10-05Clinical Trial Update: Immunogenicity of 13-valent Pneumococcal Conjugate Vaccine Compared to the Pneumococcal Polysaccharide Vaccine in Adult Kidney and Liver Transplant Patients [Phase 4]
Phase 4 trial evaluating the immunogenicity of a 13-valent pneumococcal conjugate vaccine compared with the pneumococcal polysaccharide vacc…
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: Autoregulation Assessment During Liver Transplantation
This is an update of a completed clinical trial evaluating autoregulation during liver transplantation.
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CLINICAL_TRIALS trial_result · 2017-07-19Clinical Trial Update: A Study to Assess the Pharmacokinetics, Safety and Efficacy of Advagraf and Prograf in de Novo Liver Transplantation [Phase 4]
This Phase 4 study assesses the pharmacokinetics, safety, and efficacy of Advagraf (tacrolimus extended-release) versus Prograf (tacrolimus)…
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CLINICAL_TRIALS trial_result · 2017-06-08Clinical Trial Update: Immunosuppression Withdrawal for Stable Pediatric Liver Transplant Recipients [Phase 2]
Phase 2 trial update on immunosuppression withdrawal in stable pediatric liver transplant recipients; results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-06-07Clinical Trial Update: Efficacy and Safety of Cyclosporine Microemulsion in Diabetic Adult Stable Liver Transplant Recipients [Phase 4]
Phase 4 trial update on the efficacy and safety of cyclosporine microemulsion in diabetic adult stable liver transplant recipients.
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CLINICAL_TRIALS research · 2017-06-05Clinical Trial Update: Post Static Cold Storage Normothermic Machine Liver Perfusion [Phase 1, Phase 2]
This document provides an update on a Phase 1/Phase 2 clinical trial evaluating post-static cold storage normothermic machine perfusion for …
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FDA approval · 2017-03-31FDA Approved: MYCOPHENOLATE MOFETIL — Original Application (Mylan Institutional LLC)
The FDA approved the original application for mycophenolate mofetil from Mylan Institutional LLC. It is indicated to prevent organ transplan…
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CLINICAL_TRIALS trial_result · 2017-03-30Clinical Trial Update: Extracorporeal Photopheresis in Liver Transplantation. Phase II Clinical Trial in Safety and Efficacy in Patients With Gradual Decrease of Immunosuppression. [Phase 1, Phase 2]
This clinical trial update reports the completion of a Phase I/II study examining extracorporeal photopheresis in liver transplant recipient…
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CLINICAL_TRIALS trial_result · 2017-03-29Clinical Trial Update: Role of Human Leukocyte Antigen Matching in Liver Transplantation and Its Relation to Outcomes
A clinical trial update from Ain Shams University examines how human leukocyte antigen matching influences outcomes after liver transplantat…
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CLINICAL_TRIALS trial_result · 2017-03-24Clinical Trial Update: Endotracheal Cardiac Output Monitor (ECOM) for Patients Undergoing Liver Transplantation
The clinical trial evaluating an endotracheal cardiac output monitor (ECOM) in liver transplantation was terminated, ending enrollment and a…
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CLINICAL_TRIALS trial_result · 2017-03-15Clinical Trial Update: Adefovir Plus Vaccination in Transplant Patients Without Hepatitis B That Receive a Core Antibody Positive Liver [Phase 1, Phase 2]
Phase 1/2 trial investigating adefovir plus vaccination in liver transplant recipients without Hepatitis B who are core antibody positive; s…