Liver Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2018-04-03Clinical Trial Update: Preoperative Glucose Infusion: a Novel Strategy to Improve Liver Function After Liver Resection [NA]
An update on a clinical trial evaluating preoperative glucose infusion as a strategy to improve liver function after liver resection.
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CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: Terlipressin Administration in Patients Undergoing Major Liver Resection [Phase 2]
The Phase 2 trial evaluating terlipressin in patients undergoing major liver resection was terminated.
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CLINICAL_TRIALS withdrawal · 2017-11-28Clinical Trial Update: To Study and Compare the Clinical Course and Development of Organ Failure in Severe Acute Hepatitis Without Ascites, Non-cirrhotic and Cirrhotic Patients With Ascites [Acute on Chronic Liver Failure] and Acute Deterioration of Previously Decompensated Cirrhosis.
This ClinicalTrials.gov entry indicates that the study evaluating the clinical course and organ failure in severe acute hepatitis with and w…
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CLINICAL_TRIALS trial_result · 2017-10-13Clinical Trial Update: Randomized Study of Acetylcysteine in Patients With Acute Liver Failure Not Caused by Acetaminophen [Phase 3]
Phase 3 randomized trial of acetylcysteine for acute liver failure not caused by acetaminophen has completed (status: COMPLETED).
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CLINICAL_TRIALS trial_result · 2017-09-19Clinical Trial Update: Donor Simvastatin Treatment in Organ Transplantation [Phase 2, Phase 3]
Clinical trial update on donor simvastatin treatment in organ transplantation across Phase 2 and Phase 3, completed; conditions listed inclu…
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CLINICAL_TRIALS trial_result · 2017-09-01Clinical Trial Update: Central Venous Catheter Colonisation Among Critically Ill Patients in Intensive Care Units
A completed clinical trial evaluating central venous catheter colonisation in critically ill ICU patients, including individuals with sepsis…
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: Autoregulation Assessment During Liver Transplantation
This is an update of a completed clinical trial evaluating autoregulation during liver transplantation.
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CLINICAL_TRIALS research · 2017-05-30Clinical Trial Update: Comparative Study of Circulating microRNA Changes in Patients With Liver Injury and Healthy Subjects
A clinical study comparing circulating microRNA changes between patients with liver injury (including drug-induced liver injury and liver fa…
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CLINICAL_TRIALS trial_result · 2017-05-03Clinical Trial Update: Unknown Cause of Acute Liver Failure
A completed clinical trial investigating acute liver failure of unknown etiology; the update does not disclose trial results.
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CLINICAL_TRIALS research · 2017-04-25Clinical Trial Update: Safety and Efficacy of hiHep Bioartificial Liver Support System to Treat Acute Liver Failure [NA]
This clinical trial update discusses the safety and efficacy of the hiHep Bioartificial Liver Support System for treating acute liver failur…
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CLINICAL_TRIALS trial_result · 2017-02-07Clinical Trial Update: Parenteral Lipid Emulsions and the Liver Function [Phase 4]
A Phase 4 trial evaluating the impact of parenteral lipid emulsions on liver function has completed.
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CLINICAL_TRIALS trial_result · 2017-02-07Clinical Trial Update: Intraoperative Dialysis in Liver Transplantation [NA]
The University of Alberta-sponsored intraoperative dialysis trial in liver transplantation (NCT01575015) has been terminated. The study targ…
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FDA approval · 2017-01-23FDA Approved: ACETADOTE — Supplemental Application (Cumberland Pharmaceuticals Inc.)
FDA approved a supplemental application for Acetadote (acetylcysteine) from Cumberland Pharmaceuticals, resulting in an approved update to t…
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CLINICAL_TRIALS trial_result · 2016-12-08Clinical Trial Update: Gradual Withdrawal of Immune System Suppressing Drugs in Patients Receiving a Liver Transplant [Phase 2]
A Phase 2 trial evaluating gradual withdrawal of immunosuppressive therapy in liver transplant recipients; results have been posted.
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CLINICAL_TRIALS trial_result · 2016-09-28Clinical Trial Update: Renal Perfusion, Filtration and Oxygenation After Liver Transplantation -Effects of av Postoperative Blood Pressure [NA]
A clinical trial evaluating the effects of postoperative blood pressure on renal perfusion, filtration, and oxygenation after liver transpla…
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CLINICAL_TRIALS research · 2016-09-22Clinical Trial Update: Molecular Adsorbent Recirculating System (MARS®) in Hypoxic Hepatitis [Phase 2]
Phase 2 clinical trial evaluating the MARS liver support system for hypoxic/ischemic liver injury. Current status is unknown.
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CLINICAL_TRIALS research · 2016-09-12Clinical Trial Update: The Effect of Somatostatin for Treatment of Post Hepatectomy Liver Failure (PHLF) [Phase 3]
A Phase 3 clinical trial is evaluating somatostatin as a treatment for posthepatectomy liver failure, with current status not specified.
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CLINICAL_TRIALS research · 2016-08-05Clinical Trial Update: RCT Study on Granulocyte Colony-stimulating Factor(G-CSF) Treatment of Hepatic Failure [Phase 4]
This clinical trial update reports a Phase 4 randomized study of granulocyte colony-stimulating factor (filgrastim) for hepatic failure, wit…
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CLINICAL_TRIALS trial_result · 2016-07-28Clinical Trial Update: N-acetylcysteine in Non-Acetaminophen Pediatric Acute Liver Failure [Phase 3]
Phase 3 clinical trial update for N-acetylcysteine in non-acetaminophen pediatric acute liver failure. The study has completed and results w…
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CLINICAL_TRIALS trial_result · 2016-07-28Clinical Trial Update: Interstage Assessment of Remnant Liver Function in ALPPS
This completed clinical trial from Hospital Italiano de Buenos Aires evaluates interstage assessment of remnant liver function during the AL…
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CLINICAL_TRIALS research · 2016-06-24Clinical Trial Update: UC-MSC Infusion for HBV-Related Acute-on-Chronic Liver Failure [Phase 2]
Phase 2 clinical trial investigating infusion of umbilical cord-derived mesenchymal stem cells (UC-MSC) for HBV-related acute-on-chronic liv…
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CLINICAL_TRIALS trial_result · 2016-04-11Clinical Trial Update: Pharmacokinetic and Pharmacodynamic Study of IDN-6556 in ACLF [Phase 2]
Phase 2 pharmacokinetic and pharmacodynamic study of IDN-6556 in acute liver failure conditions was terminated, with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-03-31Clinical Trial Update: Extended Drug Utilization Study Among Patients Exposed to Ticagrelor, Clopidogrel and Prasugrel
This clinical trial update reports the completion of an extended drug utilization study evaluating adverse events among patients exposed to …
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CLINICAL_TRIALS trial_result · 2016-02-17Clinical Trial Update: Role of Hypertonic Saline Versus Mannitol in the Management of Raised Intracranial Pressure in Patients With ALF [NA]
This completed clinical trial compares hypertonic saline with mannitol for the management of raised intracranial pressure in patients with a…
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CLINICAL_TRIALS withdrawal · 2016-01-15Clinical Trial Update: Cardiox Liver Function Test Pivotal Trial [Phase 3]
Cardiox Corporation reports that its Phase 3 pivotal trial for the Cardiox Liver Function Test has been withdrawn.