Liver Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-06-14Clinical Trial Update: Mesenchymal Stem Cells After Renal or Liver Transplantation [Phase 1, Phase 2]
Phase 1/2 trial evaluating mesenchymal stem cells as an adjunct therapy after renal or liver transplantation completed.
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CLINICAL_TRIALS trial_result · 2022-04-07Clinical Trial Update: Intravenous Milk Thistle (Silibinin-Legalon) for Hepatic Failure Induced by Amatoxin/Amanita Mushroom Poisoning [Phase 2]
Phase 2 trial of intravenous silibinin-legalon for hepatic failure due to amatoxin/Amita mushroom poisoning was terminated with posted resul…
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CLINICAL_TRIALS trial_result · 2021-06-07Clinical Trial Update: Avatrombopag in Patients With End-stage Liver Disease and Thrombocytopenia [Phase 4]
Phase 4 trial investigating avatrombopag for thrombocytopenia in patients with liver failure and related conditions, status currently unknow…
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CLINICAL_TRIALS trial_result · 2021-05-06Clinical Trial Update: A Randomized Controlled Clinical Trial of Thymoglobulin® After Liver Transplantation [Phase 2]
A Phase 2 randomized controlled trial evaluating Thymoglobulin after liver transplantation has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-01-12Clinical Trial Update: Dual Hypothermic Oxygenated Perfusion of DCD Liver Grafts in Preventing Biliary Complications After Transplantation [Phase 3]
Phase 3 trial assessing dual hypothermic oxygenated perfusion of DCD liver grafts to prevent biliary complications after transplantation has…
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CLINICAL_TRIALS trial_result · 2020-12-22Clinical Trial Update: 13C-Methacetin Breath Test for the Prediction of Outcome in in ALI or ALF [Phase 2, Phase 3]
Phase 2/3 trial evaluating 13C-Methacetin Breath Test to predict outcomes in acute liver failure; completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-04-28Clinical Trial Update: Study to Evaluate Safety and Efficacy of LifeLiver in Acute or Acute-on-Chronic Liver Failure Patients [Phase 2]
Phase 2 clinical trial evaluating safety and efficacy of LifeLiver in acute liver failure and acute-on-chronic liver failure.
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CLINICAL_TRIALS trial_result · 2020-04-17Clinical Trial Update: Lipid Emulsions and Liver Function - Results After 5 Years. [Phase 4]
Phase 4 trial update on lipid emulsions and liver function with results after five years.
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CLINICAL_TRIALS trial_result · 2020-01-23Clinical Trial Update: Comparative FK506 Drug Levels of Once Daily Advagraf in First Nations and Caucasian Patients With Liver Transplants [Phase 4]
Phase 4 trial comparing FK506 (advagraf) drug levels between First Nations and Caucasian liver transplant patients.
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CLINICAL_TRIALS trial_result · 2020-01-22Clinical Trial Update: Chinese CLIF-C Acute-on-Chronic Liver Disease and Liver Failure Study
A completed clinical trial on acute-on-chronic liver failure in China has posted results.
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CLINICAL_TRIALS trial_result · 2020-01-09Clinical Trial Update: The Effect of Terlipressin on Recovery of Liver Function After Hepatectomy [Phase 3]
Phase 3 clinical trial assessing terlipressin for recovery of liver function after hepatectomy, with listed conditions including terlipressi…
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CLINICAL_TRIALS trial_result · 2019-08-20Clinical Trial Update: Remote Ischemic Conditioning (RIC) in Recipients of Brain Death Donor Livers - A Feasibility and Safety Study [NA]
A completed feasibility and safety study evaluating remote ischemic conditioning in recipients of brain death donor livers; results posted i…
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CLINICAL_TRIALS trial_result · 2019-04-16Clinical Trial Update: Pneumatic Reversible Portal Vein Diameter Modulation After Major Hepatectomy [Phase 1, Phase 2]
Clinical trial update on pneumatic reversible portal vein diameter modulation after major hepatectomy, spanning Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Pharmacokinetics of Caspofungin After One Dose in Patients With Liver Failure [Phase 4]
Phase 4 pharmacokinetic study assessing a single dose of caspofungin in patients with liver failure.
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CLINICAL_TRIALS trial_result · 2019-02-12Clinical Trial Update: Safety and Efficacy of ProQuad® in Children 6-24 Month Being Evaluated for Solid Organ Transplant [EARLY_Phase 1]
An early-phase 1 trial evaluated the safety and preliminary efficacy of ProQuad in children 6-24 months being evaluated for solid organ tran…
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CLINICAL_TRIALS research · 2019-02-07Clinical Trial Update: Effects on Plasma Exchange on Functional Capacity of Serum Albumin, Circulatory Dysfunction, Renal and Cerebral Function in Cirrhotic Patients With "Acute-on-chronic Liver Failure" [NA]
This document provides a clinical trial update on plasma exchange in cirrhotic patients with acute-on-chronic liver failure, focusing on eff…
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CLINICAL_TRIALS withdrawal · 2019-01-23Clinical Trial Update: Hepatocyte Transplantation for Acute Decompensated Liver Failure [Phase 1]
A Phase 1 trial evaluating hepatocyte transplantation for acute decompensated liver failure has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-10-25Clinical Trial Update: Fast-track LiveR: Study for the Early Identification of Low-risk Patients After Partial Liver Resection by the LiMAx-test [Phase 3]
Phase 3 clinical trial update for the LiMAx-test to identify low-risk patients after partial liver resection; study completed.
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CLINICAL_TRIALS trial_result · 2018-10-17Clinical Trial Update: Study to Evaluate if the Drug Vasopressin Protects the Kidneys for Patients Undergoing Liver Transplant [NA]
A completed clinical trial evaluating whether vasopressin protects the kidneys in patients undergoing liver transplantation; results posted …
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CLINICAL_TRIALS trial_result · 2018-09-20Clinical Trial Update: Safety Study of Ornithine Phenylacetate to Treat Patients With Acute Liver Failure/Severe Acute Liver Injury [Phase 2]
Phase 2 safety study of ornithine phenylacetate for acute liver failure/severe acute liver injury has completed with posted results.
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CLINICAL_TRIALS trial_result · 2018-08-22Clinical Trial Update: Safety and Efficacy of the ELAD System (ELAD) to Treat Acute Liver Failure (ALF) [Phase 2]
Phase 2 trial evaluating the ELAD System for acute liver failure was terminated; results were posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: Plasma Exchange and Continuous Hemodiafiltration in Treatment of Wilson's Disease-related Liver Failure [NA]
This clinical trial update describes the use of plasma exchange and continuous hemodiafiltration for Wilson disease-related liver failure, w…
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CLINICAL_TRIALS research · 2018-06-06Clinical Trial Update: Bacterial Infections in Cirrhotic Patients With Acute Severe Liver Injury
This clinical trial update covers research on bacterial infections in cirrhotic patients with acute severe liver injury (NCT03204591). The c…
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CLINICAL_TRIALS research · 2018-04-30Clinical Trial Update: Liver Stiffness Measurement (LSM) in Predicting Progress of Liver Fibrosis After TACE for Hepatocellular Carcinoma
The update discusses using liver stiffness measurement to predict progression of liver fibrosis after transarterial chemoembolization in hep…
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CLINICAL_TRIALS research · 2018-04-26Clinical Trial Update: Better Diagnostic Tools for Children and Adolescents With Acute Liver Failure and Chronic Liver Insufficiency
A clinical trial update focusing on improved diagnostic tools for children and adolescents with acute liver failure and chronic liver failur…