Liver Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: High-volume Versus Standard Volume Plasma Exchange in Patients With Acute Liver Failure With Cerebral Edema [NA]
This clinical trial compares high-volume versus standard-volume plasma exchange in patients with acute liver failure and cerebral edema; the…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: CytOSorb TreatMent Of Critically Ill PatientS Registry
A Clinical Trials registry update shows that CytoSorbents is recruiting for a registry trial evaluating Cytosorb hemoadsorption in criticall…
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CLINICAL_TRIALS trial_result · 2025-09-11Clinical Trial Update: Comparison of Two Liver Dialysis Systems : MARS Versus SPAD in Severe Liver Failure [NA]
This update reports on a completed clinical trial comparing two liver dialysis systems, MARS and SPAD, in patients with acute or chronic liv…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Custodiol-N Solution Compared With Custodiol Solution in Organ Transplantation (Kidney, Liver and Pancreas) [Phase 3]
A Phase 3 clinical trial comparing Custodiol-N solution with Custodiol solution in kidney, liver, and pancreas transplantation is currently …
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Transcriptional Analysis of Mechanisms in Liver Failure and Sepsis
Clinical trial from the University of Cambridge investigating transcriptional mechanisms in acute liver failure and sepsis; the study status…
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CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: The Efficacy of Intravenous Amino Acids in Reducing the Occurrence of AKI After Live Donor Liver Transplant [NA]
This clinical trial investigates whether intravenous amino acids can reduce acute kidney injury after a live donor liver transplant, and the…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Superior Vena Cava and Its Relationship to Central Venous Pressure Measurements in Liver Transplantation
A Cleveland Clinic-sponsored clinical trial examined the relationship between superior vena cava measurements and central venous pressure du…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: CRISPR-Edited HLA Donor Liver Transplant to Reduce Rejection [Phase 1, Phase 2]
This clinical trial update describes an investigation into CRISPR-edited HLA donor livers to reduce transplant rejection, with Phase 1 and P…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Biomarkers in Liver Failure
A University of Edinburgh–sponsored biomarker study on liver failure, covering acute liver failure, acute liver injury, and acute-on-chronic…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Micro-encapsulated Hepatocyte Intraperitoneal Transplantation in Liver Failure Adults [Phase 1]
Phase 1 clinical trial evaluating micro-encapsulated hepatocytes delivered intraperitoneally for adults with liver failure is currently recr…
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CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: Continuous Renal Replacement Therapy Intensity in Hyperammonemia [NA]
A clinical trial is evaluating the effect of different intensities of continuous renal replacement therapy on hyperammonemia in patients wit…
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: Evaluation of Long Haul COVID-19 and Vaccine Immunogenicity in Patients With Liver Disease
Completed clinical trial evaluating long-haul COVID-19 and vaccine immunogenicity in patients with liver disease.
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: Perioperative Use of Amino Acids in Recipients of Orthotopic Liver Transplantation as a Renal Protective Factor [NA]
This clinical trial update describes the perioperative use of amino acids as a renal protective strategy in recipients of orthotopic liver t…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: Exploring the Application Value of New Magnetic Resonance Imaging Technologies in Non-invasive Quantitative Assessment of Graft Function After Liver Transplantation
This clinical trial update discusses applying new MRI technologies to non-invasively quantify graft function after liver transplantation. Th…
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: A Machine Learning Architecture to Predict Post-Hepatectomy Liver Failure Using Liver Regeneration Biomarkers and Time-Phased Data
A completed clinical trial reports a machine learning framework that predicts posthepatectomy liver failure using liver regeneration biomark…
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: Efficacy and Safety of Citrate Anticoagulation in CRRT for Patients With Liver Failure/DysfuncTION, the CAUTION Trial! A Retrospective Study on Etiology of Liver Failure and Their Complications
A retrospective study evaluating the etiology of liver failure and assessing the efficacy and safety of citrate anticoagulation used during …
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Clinical Study of Pediatric Acute Liver Failure
An ongoing pediatric clinical study investigating acute liver failure is currently enrolling by invitation.
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: Recompensation of Exacerbated Liver Insufficiency With Hyperbilirubinemia and/or Encephalopathy and/or Renal Failure [NA]
This is a clinical trial update noting the completion of a study focused on recompensation of exacerbated liver insufficiency presenting wit…
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: Plasma Exchange for Amanita Toxin-induced Acute Liver Failure
A Hannover Medical School-sponsored clinical trial evaluated plasma exchange for Amanita toxin-induced acute liver failure and has completed…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Role of N-Acetylcysteine in Non-Acetaminophen-Induced Acute Liver Failure [NA]
Clinical trial investigating N-acetylcysteine for non-acetaminophen-induced acute liver failure; status is active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: A Comparative Analysis of Preoperative Liver Volumetry in Living Donor Liver Transplantation
A completed clinical trial evaluating preoperative liver volumetry techniques in the setting of living donor liver transplantation.
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CLINICAL_TRIALS trial_result · 2025-03-03Clinical Trial Update: Efficacy of Albumin Dialysis to Treat Patients With Hepatic Encephalopathy Using The Molecular Adsorbent Recirculating System (MARS) [NA]
A completed clinical trial evaluated the efficacy of albumin dialysis using the MARS system to treat hepatic encephalopathy in patients with…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: The Safety ,Tolerability and Efficacy Study of HepaCure in Chinese Subjects with Acute-On-Chronic Liver Failure [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial assessing the safety, tolerability, and preliminary efficacy of HepaCure in Chinese patients with acute-on-…
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CLINICAL_TRIALS trial_result · 2025-02-25Clinical Trial Update: Continuous Renal Replacement Therapy (CRRT) in Surgery Room During Orthotopic Liver Transplantation (OLT) [NA]
A completed clinical trial evaluating continuous renal replacement therapy (CRRT) in the operating room during orthotopic liver transplantat…
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Correlation of Blood Gene Expression (TruGraf Liver) With Liver Biopsy in Pediatric Liver Transplant Recipients
A terminated clinical trial assessing how TruGraf Liver blood gene expression correlates with liver biopsy findings in pediatric liver trans…