Liver Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-07-22Clinical Trial Results: Bridge to HOPE: Hypothermic Oxygenated Perfusion Versus Cold Storage Prior to Liver Transplantation [NA]
A completed clinical trial comparing hypothermic oxygenated perfusion versus cold storage prior to liver transplantation.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Pharmacokinetics and Safety of MDR-001 in Mild and Moderate Hepatic Impairment [Phase 1]
Phase 1 trial update evaluating pharmacokinetics and safety of MDR-001 in mild and moderate hepatic impairment; status is not yet recruiting…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Hepato Biliary Scintigraphy to Assess the Risk of Postoperative Liver Failure Hepatectomies [NA]
This entry reports the completion status of a clinical trial evaluating hepatobiliary scintigraphy to assess the risk of postoperative liver…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Safety and Tolerability Study of a Novel Bioartificial Liver in Liver Failure and Small-for-Size Syndrome [Phase 1, Phase 2]
This clinical trial update describes safety and tolerability testing of a novel bioartificial liver for liver failure and small-for-size syn…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Safety and Effectiveness of Mesenchymal Stem Cells in Blood Purification for the Treatment of Liver Failure [Phase 1]
Phase 1 clinical trial assessing the safety and effectiveness of mesenchymal stem cells used in blood purification for liver failure; study …
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Study on Relationship Between Resected Normal Liver Parenchymal Volume（RNLV）and Post-Hepatectomy Liver Failure (PHLF)
A National Natural Science Foundation of China–funded clinical trial studies the relationship between resected normal liver parenchymal volu…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Ex Vivo Perfusion of Gene-Edited Porcine Livers in Patients With Severe Hepatic Failure [EARLY_Phase 1]
An early-phase trial is evaluating ex vivo perfusion of gene-edited porcine livers in patients with severe hepatic failure. The study status…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Raltegravir in Patients With End Stage Liver Disease and in Transplant Recipients [Phase 1, Phase 2]
Phase 1/2 trial update on raltegravir in patients with end-stage liver disease and in liver transplant recipients, reporting safety and phar…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Pyrophosphate Homeostasis and Hepatic Expression of ABCC6.Pyro-TH [NA]
This trial update reports completion of a study on pyrophosphate homeostasis and hepatic ABCC6 expression in hepatic failure.
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: TReatment for ImmUne Mediated PathopHysiology [Phase 2]
A Phase 2 clinical trial sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases is recruiting to treat immune-med…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: miroliverELAP® for the Treatment of Acute Liver Failure: A Phase 1 Trial [Phase 1]
Phase 1 trial of miroliverELAP for acute liver failure has been completed. The document provides an update on the trial status by Miromatrix…
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CLINICAL_TRIALS trial_result · 2026-02-24Clinical Trial Update: Safety and Clinical Activity of QEL-001 in A2-mismatch Liver Transplant Patients [Phase 1, Phase 2]
Phase 1/2 data on QEL-001 in A2-mismatch liver transplant patients show safety and preliminary clinical activity in the setting of transplan…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Empagliflozin in Patients With Cirrhosis and Ascites [Phase 2]
A Phase 2 clinical trial evaluating empagliflozin in patients with cirrhosis and ascites is currently recruiting at Yale University.
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Single-Cell and Spatial Transcriptomics Analysis of Steatotic Donor Liver Susceptibility to Post-Transplant Injury
This completed clinical trial analyzed single-cell and spatial transcriptomics to investigate how steatotic donor livers are susceptible to …
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Diagnosis of Lymphohistiocytic Hemophagocytosis in Intensive Care
A clinical trial at University Hospital Strasbourg is evaluating diagnostic approaches for hemophagocytic lymphohistiocytosis in intensive c…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: ALSS - DPMAS and Therapeutic Plasma Exchange (TPE), Its Effect on Primary Coagulation, Inflammation and the Function of Vital Organs in ALF or ACLF [NA]
Clinical trial update on ALSS using DPMAS and therapeutic plasma exchange to assess effects on coagulation, inflammation and organ function …
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Abdominal Wall Transplant [NA]
Duke University is sponsoring a recruiting clinical trial evaluating abdominal wall transplantation for patients with abdominal wall defects…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Standard Volume vs. High Volume Plasma Exchange in Pediatric Acute Liver Failure [NA]
A pediatric clinical trial comparing standard-volume versus high-volume plasma exchange for acute liver failure is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: Biliary Anastomosis Using Surgical Loupe Versus Microscope in Living Donor Liver Transplantation [NA]
This clinical trial compared biliary anastomosis using a surgical loupe versus a microscope in living donor liver transplantation. The study…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Addiction Intervention in Liver Transplantation Candidates [NA]
An ongoing clinical trial in Montpellier is evaluating an addiction intervention for liver transplant candidates; the study is active but no…
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CLINICAL_TRIALS trial_result · 2025-11-25Clinical Trial Update: Evaluation of the Efficacy of Fomepizole in the Treatment of Acetaminophen Overdose [Phase 2]
A Phase 2 trial evaluating fomepizole for acetaminophen overdose was terminated; no efficacy results are reported.
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: F573 for Injection for the Treatment of Liver Injury/Failure [Phase 2]
Phase 2 clinical trial update for F573 for Injection in acute liver failure and acute-on-chronic liver failure, currently recruiting.
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: The Microbiota Augmentation to Reestablish Commensal Organisms (MARCO) Trial [Phase 1]
Phase 1 clinical trial MARCO (Microbiota Augmentation to Reestablish Commensal Organisms) investigating a microbiota-based therapy for liver…
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: Longitudinal Study of Mitochondrial Hepatopathies
The longitudinal study of mitochondrial hepatopathies is currently suspended.
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CLINICAL_TRIALS trial_result · 2025-10-06Clinical Trial Update: Assessment of Renal Function in Cirrhotic Patients
A completed clinical trial assessing renal function in patients with cirrhosis.