Liver Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-09-12Clinical Trial Update: Shear Wave Sonoelastography in Pediatric Liver Fibrosis
A pediatric trial evaluating shear wave sonoelastography for assessing liver fibrosis has completed and posted results.
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CLINICAL_TRIALS trial_result · 2019-07-24Clinical Trial Update: Prospective Analysis of Value of Contrast-enhanced Sonography During Biopsies of Focal Liver Masses [Phase 4]
Phase 4 trial update evaluating the value of contrast-enhanced sonography during biopsies of focal liver masses; study terminated with poste…
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CLINICAL_TRIALS trial_result · 2019-05-07Clinical Trial Update: 3T MR Angiography of the Hepatic Vasculature [NA]
A terminated clinical trial study investigating 3T MR angiography of the hepatic vasculature; results were posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-04-23Clinical Trial Update: Implication of Fluid Strategies Upon Hepatic Outcome in Hepatobiliary Surgery [Phase 1, Phase 2]
A clinical trial update examining how fluid management strategies affect hepatic outcomes after hepatobiliary surgery, currently in Phase 1 …
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CLINICAL_TRIALS trial_result · 2019-03-11Clinical Trial Update: Detection of Liver Fibrosis With Magnetic Resonance Imaging (MRI) [Phase 4]
Phase 4 clinical trial updating on detecting liver fibrosis using MRI in chronic liver disease.
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CLINICAL_TRIALS approval · 2019-02-12Clinical Trial Update: Compassionate Use of IV Fish Oil for Parenteral Nutrition (PN) Liver Injury
IV fish oil for parenteral nutrition–associated liver injury has been approved for marketing, marking regulatory clearance for this therapy …
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CLINICAL_TRIALS research · 2019-02-08Clinical Trial Update: Nottingham Community Liver Biomarkers Cohort
Status update on the Nottingham Community Liver Biomarkers Cohort trial, sponsored by the University of Nottingham, which is currently recru…
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CLINICAL_TRIALS trial_result · 2019-02-06Clinical Trial Update: Compassionate Use of Omegaven in the Treatment of Parenteral Nutrition Induced Hepatic Injury [NA]
This clinical trial update notes the completion of a compassionate-use study of Omegaven for parenteral nutrition-associated liver disease. …
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CLINICAL_TRIALS trial_result · 2019-01-08Clinical Trial Update: Oral Hepatitis C Treatment for Indolent Lymphoma (OPTImaL) Study [Phase 4]
Phase 4 clinical trial update for an oral hepatitis C treatment in indolent lymphoma; study terminated with posted results.
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CLINICAL_TRIALS trial_result · 2018-10-15Clinical Trial Update: Study Evaluating Novel Biomarkers of AKI (Acute Kidney Injury) in Post-operative Patients [Phase 4]
Phase 4 clinical trial evaluating novel biomarkers of acute kidney injury in post-operative patients was terminated.
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CLINICAL_TRIALS trial_result · 2018-10-12Clinical Trial Update: A Study of Evacetrapib (LY2484595) in Participants With Hepatic (Liver) Impairment [Phase 1]
Phase 1 trial update assessing Evacetrapib in participants with hepatic impairment has completed and results posted.
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CLINICAL_TRIALS trial_result · 2018-09-25Clinical Trial Update: Safety and Efficacy Study of Lusutrombopag for Thrombocytopenia in Patients With Chronic Liver Disease Undergoing Elective Invasive Procedures [Phase 3]
Phase 3 trial assessing safety and efficacy of lusutrombopag for thrombocytopenia in patients with chronic liver disease undergoing invasive…
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CLINICAL_TRIALS trial_result · 2018-08-06Clinical Trial Update: Terlipressin Alone Versus the Standard Therapy With Catecholamines for Hepatic Patients With Septic Shock- Prospective Single Center Randomized Controlled Study. [Phase 2, Phase 3]
Prospective single-center randomized trial comparing terlipressin alone to standard catecholamine therapy for hepatic patients with septic s…
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FDA approval · 2018-07-31FDA Approved: MULPLETA — Original Application (Eddingpharm (U. S. ) Inc.)
The FDA granted original approval for Mulpleta (lusutrombopag) for adults with chronic liver disease to raise platelet counts in advance of …
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CLINICAL_TRIALS trial_result · 2018-07-20Clinical Trial Update: Outcomes of Liver Transplantation in Low Weight Children After Reducing the Lateral Segment of a Living Donor, Adapting the Shape and Size of the Graft to the Needs of the Recipient
A completed clinical trial evaluating liver transplantation in very low-weight children using hyper-reduced grafts from living donors, with …
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: Non-invasive Biomarkers of Fibrosis in Pediatric Liver Diseases
This completed pediatric trial from Baylor College of Medicine evaluated non-invasive biomarkers to detect liver fibrosis in children with v…
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: Evaluation of the Effect of Gabexate Mesilate in the Hepatocyte Protection After Liver Resection [Phase 3]
Phase 3 trial evaluating gabexate mesilate for hepatocyte protection after liver resection was terminated.
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CLINICAL_TRIALS research · 2018-07-18Clinical Trial Update: Haemostatic Imbalance in Patients With Chronic Liver Disease
This clinical trial update describes haemostatic imbalance in patients with chronic liver disease and notes that the study status is current…
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CLINICAL_TRIALS other · 2018-07-18Clinical Trial Update: Clinical Features and Natural History of Acute-on-Chronic Liver Failure in Korean Patients With Chronic Liver Disease
This clinical trial update notes that the study on acute-on-chronic liver failure in Korean patients with chronic liver disease has been sus…
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CLINICAL_TRIALS trial_result · 2018-07-03Clinical Trial Update: Portal Blood Flushes in the Peri-Reperfusion Stage of Liver Transplantation
A completed clinical trial from the Medical University of South Carolina evaluated portal blood flushes during the peri-reperfusion phase of…
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CLINICAL_TRIALS trial_result · 2018-06-19Clinical Trial Update: Immunological Measurement of Aspartate/Alanine Aminotransferase
This clinical trial update reports immunological measurements of aspartate aminotransferase and alanine aminotransferase in participants wit…
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CLINICAL_TRIALS withdrawal · 2018-06-18Clinical Trial Update: Minocycline Administration During Human Liver Transplantation [Phase 4]
This Phase 4 trial evaluating minocycline administration during human liver transplantation has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-05-23Clinical Trial Update: Vitamin D Levels in Liver Transplantation Recipients Prospective Observational Study
A completed prospective observational study evaluating vitamin D levels in liver transplant recipients. Sponsored by The Mediterranean Insti…
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FDA approval · 2018-05-21FDA Approved: DOPTELET — Original Application (AkaRx, Inc.)
FDA approved DOPTELET (avatrombopag) from AkaRx, Inc. for reducing the need for platelet transfusions in adults with chronic liver disease u…
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CLINICAL_TRIALS withdrawal · 2018-04-19Clinical Trial Update: Inhibition of VAP-1 by Caffeine in Healthy Human Volunteers Study [Phase 1]
Phase 1 trial evaluating caffeine as an inhibitor of VAP-1 in healthy volunteers was withdrawn; the study was associated with liver disease …