Liver Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-04-25Clinical Trial Update: Effect of Heavy Alcohol Consumption on Farnesoid X Receptor (FXR) Signaling [NA]
A completed clinical trial evaluated how heavy alcohol consumption affects Farnesoid X Receptor (FXR) signaling.
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CLINICAL_TRIALS trial_result · 2023-04-05Clinical Trial Update: Effectiveness of Oral Lactulose Versus Lactulose Enema in Hepatic Encephalopathy [Phase 4]
Phase 4 trial update evaluating the effectiveness of oral lactulose versus lactulose enema in hepatic encephalopathy.
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CLINICAL_TRIALS trial_result · 2022-11-15Clinical Trial Update: Efficacy of Avatrombopag in Thrombocytopenic Patients With Chronic Liver Disease Undergoing an Elective Procedure [Phase 4]
Phase 4 clinical trial evaluating avatrombopag for thrombocytopenia in patients with chronic liver disease undergoing an elective procedure.
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CLINICAL_TRIALS trial_result · 2022-11-02Clinical Trial Update: A Clinical Trial Evaluating the Efficacy, Safety, and Pharmacokinetics of HSK21542 Injection in Liver Disease Subjects With Pruritus [Phase 2]
Phase 2 trial evaluating HSK21542 injection for pruritus in liver disease completed.
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CLINICAL_TRIALS trial_result · 2022-03-18Clinical Trial Update: Study Comparing in Livertransplantation Recipients With Tacrolimus Alone Versus Tacrolimus&Sirolimus [Phase 4]
A Phase 4 trial comparing tacrolimus alone versus tacrolimus with sirolimus in liver transplant recipients has completed.
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FDA label_change · 2021-12-28FDA Approved: EOVIST — Supplemental Application (Bayer HealthCare Pharmaceuticals Inc.)
FDA approved a supplemental application for EOVIST (gadoxetate disodium) to update the product labeling.
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CLINICAL_TRIALS trial_result · 2021-12-01Clinical Trial Update: Treatment of Chronic Delta Hepatitis With Lonafarnib, Ritonavir and Lambda Interferon [Phase 2]
Phase 2 trial evaluating lonafarnib, ritonavir, and lambda interferon for chronic hepatitis D has completed with posted results.
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FDA approval · 2021-10-14FDA Approved: DOPTELET — Supplemental Application (AkaRx, Inc.)
FDA approved a supplemental application for DOPTELET (avatrombopag maleate) from AkaRx, Inc., likely to modify the label or add/expand an in…
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CLINICAL_TRIALS trial_result · 2021-10-06Clinical Trial Update: Proof of Concept Study Concerning Efficacy of P03277 MR Imaging in HCC Diagnosis [Phase 2]
A Phase 2 proof-of-concept study evaluating the efficacy of P03277 MR imaging for diagnosing hepatocellular carcinoma.
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CLINICAL_TRIALS trial_result · 2021-09-02Clinical Trial Update: APAP-CYS Protein Adduct Concentrations in Patients With Liver-Directed Therapy Intended to Treat Hepatic Tumors [Phase 4]
Clinical trial update for APAP-CYS protein adduct concentrations in patients undergoing liver-directed therapy for hepatic tumors; study wit…
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CLINICAL_TRIALS trial_result · 2021-08-13Clinical Trial Update: Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension [Phase 4]
Phase 4 trial update on noninvasive subharmonic aided pressure estimation for portal hypertension in liver disease.
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CLINICAL_TRIALS trial_result · 2021-06-29Clinical Trial Update: Spironolactone After Liver Transplant [Phase 4]
Phase 4 clinical trial update on spironolactone after liver transplant completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-02-05Clinical Trial Update: Correlation and Comparison of the HepQuant® Disease Severity Index (DSI) With Hepatic Venous Pressure Gradient (HVPG) [Phase 3]
Phase 3 clinical trial comparing HepQuant DSI with HVPG in liver disease has completed with results posted.
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CLINICAL_TRIALS research · 2020-11-16Clinical Trial Update: deLIVER: Direct Acting Antiviral Effects on the Liver [Phase 4]
A Phase 4 trial update evaluating direct-acting antivirals' effects on the liver in patients with hepatitis C coinfection and liver disease;…
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CLINICAL_TRIALS trial_result · 2020-09-24Clinical Trial Update: Comparison of Hydro-dissection Versus Ultrasonic Aspirator in Division of Liver Parenchyma in Laparoscopic Resection [NA]
Completed clinical trial comparing hydro-dissection versus ultrasonic aspirator for liver parenchyma division during laparoscopic liver rese…
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CLINICAL_TRIALS research · 2020-09-18Clinical Trial Update: Immunity Against Varicella in Pediatric Orthotopic Liver Transplantation Recipients [Phase 2, Phase 3]
A pediatric trial update evaluating immunity against varicella in liver transplant recipients undergoing immunosuppression (Phase 2/Phase 3)…
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CLINICAL_TRIALS trial_result · 2020-09-01Clinical Trial Update: Magnetic Resonance Elastography in Infants [NA]
Clinical trial update for Magnetic Resonance Elastography in infants studying liver disease; study terminated with results posted.
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FDA approval · 2020-08-20FDA Approved: DOPTELET — Supplemental Application (AkaRx, Inc.)
FDA approved a supplemental application for DOPTELET (avatrombopag maleate) from AkaRx, Inc., likely expanding labeling or indications.
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CLINICAL_TRIALS trial_result · 2020-08-11Clinical Trial Update: Efficacy and Safety of Glucocorticosteroid Treatment in the Patients With Chronic Recurrent DILI [Phase 1, Phase 2]
Clinical trial investigating the efficacy and safety of glucocorticosteroid treatment in patients with chronic recurrent drug-induced liver …
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CLINICAL_TRIALS research · 2020-07-31Clinical Trial Update: Controlled Attenuation Parameter (CAP) in Liver Allografts
A completed clinical trial examining the use of controlled attenuation parameter (CAP) to assess liver allografts in liver transplant patien…
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CLINICAL_TRIALS trial_result · 2019-10-31Clinical Trial Update: A Phase I/II Safety and Tolerability Dose Escalation Study of Autologous Stem Cells to Patients With Liver Insufficiency [Phase 1, Phase 2]
Phase I/II trial evaluating autologous stem cell therapy for liver insufficiency; completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-10-29Clinical Trial Update: Prospective Validation of a Plasma Transfusion Dosing Algorithm in Patients With Chronic Liver Disease [Phase 4]
A Phase 4 trial validating a plasma transfusion dosing algorithm in patients with chronic liver disease has completed with posted results.
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CLINICAL_TRIALS research · 2019-10-28Clinical Trial Update: Beyond Confounders: Addressing Source of Measurement Variability and Error in Shear Wave Elastography [NA]
Clinical trial update on addressing measurement variability and error in shear wave elastography for liver conditions, with completed status…
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CLINICAL_TRIALS trial_result · 2019-10-08Clinical Trial Update: Evaluate the Efficacy and Safety of Sofosbuvir/Velpatasvir Fixed-Dose Combination and Ribavirin for 12 Weeks in Participants With Chronic HCV Infection and Child-Pugh-Turcotte Class C Cirrhosis [Phase 2]
Phase 2 trial evaluating sofobuvir/velpatasvir with ribavirin for 12 weeks in chronic HCV with Child-Pugh C cirrhosis; results posted in 201…
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CLINICAL_TRIALS trial_result · 2019-09-27Clinical Trial Update: Prediction Value of the BreathID 13C-Methacetin Breath Test for Hepatic Decompensation
A completed clinical trial evaluating the predictive value of the BreathID 13C-Methacetin breath test for hepatic decompensation in chronic …