Liver Cirrhosis
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Sign up freeTop drugs studied for this disease
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FDA approval · 2013-06-12FDA Approved: ALDACTONE — Supplemental Application (Pfizer Laboratories Div Pfizer Inc)
FDA approved a supplemental application for Aldactone (spironolactone) from Pfizer. The approval updates the drug’s labeling.
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CLINICAL_TRIALS trial_result · 2013-04-18Clinical Trial Update: Treatment of Sodium Retention in Liver Cirrhosis With Dexamethasone [Phase 3]
A Phase 3 trial evaluating dexamethasone for sodium retention in liver cirrhosis has been terminated. The study was sponsored by Insel Grupp…
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CLINICAL_TRIALS trial_result · 2013-03-07Clinical Trial Update: Fuzheng Huayu Tablets Against Posthepatitic Cirrhosis [Phase 4]
Phase 4 clinical trial of Fuzheng Huayu Tablets for posthepatitic cirrhosis has been completed.
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CLINICAL_TRIALS trial_result · 2013-01-09Clinical Trial Update: Effect of Saccharomyces Boulardii in Patients in the Waiting List for Liver Transplant [Phase 2]
Phase 2 trial results evaluating Saccharomyces boulardii in patients with liver cirrhosis on the liver transplant waiting list.
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FDA approval · 2013-01-07FDA Approved: TORSEMIDE — Supplemental Application (Camber Pharmaceuticals, Inc.)
FDA approved Camber Pharmaceuticals' torsemide supplemental application (ANDA 079234), resulting in an approved updated torsemide product un…
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CLINICAL_TRIALS trial_result · 2013-01-07Clinical Trial Update: Resting Energy Expenditure in Patients on the Waiting List for Liver Transplantation
This study reports results on resting energy expenditure in patients awaiting liver transplantation, contributing to understanding metabolic…
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CLINICAL_TRIALS trial_result · 2012-12-20Clinical Trial Update: B-type Natriuretic Peptide in the Diagnosis of Heart Failure Related Ascites [NA]
Completed clinical trial evaluating whether B-type natriuretic peptide can aid diagnosis of heart failure-related ascites in patients with h…
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CLINICAL_TRIALS trial_result · 2012-12-17Clinical Trial Update: HVPG for Rebleeding Risk Stratification
This clinical trial update describes the use of hepatic venous pressure gradient (HVPG) for stratifying rebleeding risk in patients with liv…
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FDA approval · 2012-11-30FDA Approved: FUROSEMIDE — Supplemental Application (Ipca Laboratories Limited)
The FDA approved a supplemental application for furosemide from Ipca Laboratories Limited, indicating approval of their generic furosemide p…
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CLINICAL_TRIALS trial_result · 2012-11-20Clinical Trial Update: Safety and Efficacy of Human Autologous Peripheral Blood Stem Cells for Treatment of HBV-related Liver Cirrhosis [Phase 1, Phase 2]
A Phase 1/2 clinical trial investigates autologous peripheral blood stem cell therapy for HBV-related liver cirrhosis, reporting safety and …
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CLINICAL_TRIALS trial_result · 2012-11-20Clinical Trial Update: Safety and Efficacy of Human Umbilical Cord Derived Mesenchymal Stem Cells for Treatment of HBV-related Liver Cirrhosis [Phase 1, Phase 2]
Phase 1/2 trial assessing the safety and potential efficacy of human umbilical cord-derived mesenchymal stem cells for HBV-related liver cir…
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CLINICAL_TRIALS trial_result · 2012-11-19Clinical Trial Update: Steroid Free Immunosuppression in Liver Transplantation [Phase 4]
Phase 4 clinical trial update showing results of a steroid-free immunosuppression strategy in liver transplantation; the study is completed …
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CLINICAL_TRIALS research · 2012-11-12Clinical Trial Update: Safety and Efficacy of Human Bone Marrow Stem Cells for Treatment of HBV-related Liver Cirrhosis [Phase 1, Phase 2]
Clinical trial update on the safety and potential efficacy of human bone marrow stem cells for HBV-related liver cirrhosis, evaluated in Pha…
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CLINICAL_TRIALS trial_result · 2012-10-31Clinical Trial Update: Difference in Efficacy Between Stem Cell Transplantation and Classical Therapy in Liver Cirrhosis Patients [Phase 1, Phase 2]
A clinical trial compares stem cell transplantation to classical therapy in liver cirrhosis patients, spanning Phase 1 and Phase 2. The curr…
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CLINICAL_TRIALS trial_result · 2012-10-26Clinical Trial Update: Safety and Efficacy of Stem Cell Transplantation for Treatment of Liver Cirrhosis [Phase 2, Phase 3]
This clinical trial update reports on the safety and efficacy of stem cell transplantation for liver cirrhosis in Phase 2 and Phase 3.
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CLINICAL_TRIALS research · 2012-10-24Clinical Trial Update: The Perioperative Value of Platelet Counts in Predicting Outcome After Liver Transplantation
This clinical trial investigates whether perioperative platelet counts can predict complications or death after liver transplantation.
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CLINICAL_TRIALS trial_result · 2012-10-18Clinical Trial Update: Liver Regeneration Therapy Using Autologous Adipose Tissue Derived Stromal Cells [Phase 1]
Phase 1 trial evaluating autologous adipose tissue–derived stromal cells for liver regeneration in liver cirrhosis; the study was terminated…
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CLINICAL_TRIALS trial_result · 2012-10-17Clinical Trial Update: Keyhole Limpet Hemocyanin in Chronic Hepatitis C [NA]
A completed clinical trial investigating Keyhole Limpet Hemocyanin in patients with chronic hepatitis C and liver cirrhosis.
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CLINICAL_TRIALS trial_result · 2012-07-18Clinical Trial Update: Everolimus in de Novo Liver Transplantation: a Multicentre Randomized Study [Phase 2]
Phase 2 multicentre randomized trial evaluating everolimus for immunosuppression in de novo liver transplantation.
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FDA label_change · 2012-07-11FDA Approved: FUROSEMIDE — Supplemental Application (Chartwell RX, LLC)
FDA approved a supplemental application for furosemide from Chartwell RX, LLC, resulting in changes to the drug's labeling.
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CLINICAL_TRIALS trial_result · 2012-06-26Clinical Trial Update: Hepatic Sugar Metabolism Measured by PET/CT in Patients and Healthy Subjects
A completed clinical trial evaluated hepatic sugar metabolism using PET/CT in patients with liver cirrhosis and in healthy subjects.
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CLINICAL_TRIALS trial_result · 2012-06-19Clinical Trial Update: Cerebral Oxygen, Blood Flow and Ammonia Uptake in Patients With Cirrhosis and an Acute Episode of Hepatic Encephalopathy (HE)
A completed clinical trial evaluating cerebral oxygenation, cerebral blood flow, and ammonia uptake in patients with cirrhosis and an acute …
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CLINICAL_TRIALS research · 2012-06-07Clinical Trial Update: Human Menstrual Blood-derived Mesenchymal Stem Cells for Patients With Liver Cirrhosis [Phase 1, Phase 2]
Clinical trial update on using human menstrual blood-derived mesenchymal stem cells to treat liver cirrhosis (Phase 1/Phase 2).
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FDA approval · 2012-05-11FDA Approved: FUROSEMIDE — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA approved a supplemental application for furosemide by Hikma Pharmaceuticals USA Inc., authorizing a generic version of the diuretic. Thi…
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CLINICAL_TRIALS trial_result · 2012-04-23Clinical Trial Update: Banding Versus Propranolol for Primary Prophylaxis of Variceal Bleeding [Phase 3]
A Phase 3 trial comparing endoscopic variceal band ligation to propranolol for primary prophylaxis of variceal bleeding in patients with liv…