Liver Cirrhosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-12-11Clinical Trial Update: A Trial of IDN-6556 in Post Orthotopic Liver Transplant for Chronic HCV [Phase 2]
Phase 2 trial of IDN-6556 in post-orthotopic liver transplant patients with chronic hepatitis C-related liver disease has completed with res…
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CLINICAL_TRIALS trial_result · 2019-11-22Clinical Trial Update: Palliative Care for Non-Malignant Diseases (COMPASS Trial) [NA]
Clinical trial update for the COMPASS trial on palliative care in non-malignant liver diseases, terminated with posted results in 2019.
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CLINICAL_TRIALS trial_result · 2019-10-28Clinical Trial Update: Antibiotic Prophylaxis in Patients Undergoing GVO [Phase 4]
Phase 4 clinical trial updating antibiotic prophylaxis for patients undergoing GVO (gastric variceal obliteration) with conditions including…
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CLINICAL_TRIALS trial_result · 2019-10-23Clinical Trial Update: Dose-ranging Study of Rifaximin Soluble Solid Dispersion (SSD) Tablets for the Prevention of Complications of Early Decompensated Liver Cirrhosis [Phase 2]
Phase 2 dose-ranging trial evaluating rifaximin SSD tablets to prevent complications in early decompensated liver cirrhosis has completed.
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CLINICAL_TRIALS trial_result · 2019-10-03Clinical Trial Update: Adult Stem Cell Therapy in Liver Insufficiency [NA]
A completed clinical trial update on an adult stem cell therapy for liver cirrhosis, with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-09-30Clinical Trial Update: Hepatic Venous Pressure Gradient-guided Versus Standard Beta-blocker Therapy in Primary Prevention of Variceal Bleeding [Phase 3]
Phase 3 trial comparing hepatic venous pressure gradient-guided beta-blocker therapy to standard beta-blocker therapy for primary prevention…
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CLINICAL_TRIALS trial_result · 2019-09-04Clinical Trial Update: A Randomized Trial of GVS Alone vs. Propranolol [Phase 4]
A randomized phase 4 trial comparing GVS alone to propranolol in patients with bleeding gastric varices and liver cirrhosis.
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CLINICAL_TRIALS trial_result · 2019-08-30Clinical Trial Update: Open Label Trial of Immunotherapy for Advanced Liver Cancer [Phase 2]
Open-label Phase 2 trial update of an immunotherapy for advanced liver cancer, with conditions including hepatocellular carcinoma and liver …
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FDA approval · 2019-08-06FDA Approved: CHLORTHALIDONE — Original Application (Unichem Pharmaceuticals (USA), Inc.)
FDA approved the original application for chlorthalidone from Unichem Pharmaceuticals (USA), Inc., enabling a generic version of the diureti…
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FDA approval · 2019-07-12FDA Approved: ETHACRYNIC ACID — Original Application (TRUPHARMA LLC)
FDA approves the original ANDA for Ethacrynic acid by Trupharma LLC, enabling its generic distribution as a loop diuretic. The approval cove…
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CLINICAL_TRIALS withdrawal · 2019-06-14Clinical Trial Update: Fresh Frozen Plasma as a Substitute for Albumin in Patients Receiving a Large Volume Paracentesis [Phase 4]
A Phase 4 trial evaluating fresh frozen plasma as a substitute for albumin in patients undergoing large volume paracentesis has been withdra…
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CLINICAL_TRIALS trial_result · 2019-06-07Clinical Trial Update: Study of Orphenadrine' in the Treatment of Muscle Cramps in Patients With Cirrhosis [Phase 3]
Phase 3 clinical trial investigating orphenadrine for muscle cramps in patients with liver cirrhosis is currently recruiting.
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CLINICAL_TRIALS trial_result · 2019-05-22Clinical Trial Update: [18F]FMISO PET/CT After Transcatheter Arterial Embolization in Imaging Tumors in Patients With Liver Cancer [Phase 2]
Phase 2 clinical trial evaluating [18F]FMISO PET/CT after transcatheter arterial embolization in adult liver cancer patients has completed w…
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CLINICAL_TRIALS trial_result · 2019-03-28Clinical Trial Update: Simvastatin Plus Rifaximin in Decompensated Cirrhosis [Phase 2]
Phase 2 trial evaluating simvastatin plus rifaximin in decompensated cirrhosis has completed.
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CLINICAL_TRIALS research · 2019-02-18Clinical Trial Update: Prospective Evaluation of HIV Patients Using Non-invasive Methods for Estimation of Liver Fibrosis and Steatosis
Prospective clinical trial in HIV patients evaluating non-invasive methods to estimate liver fibrosis and steatosis.
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CLINICAL_TRIALS research · 2019-02-15Clinical Trial Update: Zinc Supplementation in Cirrhotic Patients [NA]
A clinical trial sponsored by Fundación Clínica Médica Sur is evaluating zinc supplementation in patients with liver cirrhosis; the status i…
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CLINICAL_TRIALS withdrawal · 2019-02-15Clinical Trial Update: Midodrine, Octreotide and Albumin: Impact on Renal Function of Patients With Liver Cirrhosis and Renal Failure [Phase 2]
A Phase 2 trial evaluating whether midodrine, octreotide, and albumin can improve renal function in patients with liver cirrhosis and renal …
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Protein Biomarker in Hepatocellular Carcinoma
This clinical trial update reports termination of a study evaluating a protein biomarker in hepatocellular carcinoma, sponsored by the Johns…
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CLINICAL_TRIALS research · 2019-02-12Clinical Trial Update: Propofol for Sedation of Postoperative Electively Ventilated Liver Transplant Recipients.
Clinical trial exploring Propofol as a sedative in postoperative, mechanically ventilated liver transplant recipients with liver cirrhosis.
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CLINICAL_TRIALS trial_result · 2019-02-08Clinical Trial Update: Adult-to-Adult Living Donor Transplant Cohort Study
The Clinical Trials entry indicates that the Adult-to-Adult Living Donor Transplant Cohort Study has completed.
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CLINICAL_TRIALS research · 2019-02-07Clinical Trial Update: Effects on Plasma Exchange on Functional Capacity of Serum Albumin, Circulatory Dysfunction, Renal and Cerebral Function in Cirrhotic Patients With "Acute-on-chronic Liver Failure" [NA]
This document provides a clinical trial update on plasma exchange in cirrhotic patients with acute-on-chronic liver failure, focusing on eff…
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CLINICAL_TRIALS trial_result · 2019-02-04Clinical Trial Update: Non-invasive Prediction of Esophageal Varices in Liver Cirrhosis: A Multicenter Observational Study
The study reports on a completed multicenter observational effort to non-invasively predict esophageal varices in patients with liver cirrho…
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CLINICAL_TRIALS trial_result · 2019-02-01Clinical Trial Update: Body Composition Analysis in Cirrhotic Undergoing Paracentesis
A clinical trial update describes studying body composition analysis in patients with liver cirrhosis undergoing paracentesis; the current s…
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CLINICAL_TRIALS research · 2019-01-31Clinical Trial Update: Evaluation of Gastrointestinal Transit Pre and Pos Treatment With Non Selective Betablocker in a Population of Cirrhotics [NA]
Clinical trial update evaluating gastrointestinal transit before and after treatment with a non-selective beta-blocker in patients with live…
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CLINICAL_TRIALS research · 2019-01-31Clinical Trial Update: Evaluation of Intestinal Permeability in Cirrhotic Patients Before and After Treatment With Non-selective Beta Blocker (Propranolol) [NA]
This clinical trial investigates intestinal permeability in patients with liver cirrhosis before and after treatment with the non-selective …