Liver Cirrhosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-06-07Clinical Trial Update: Study to Evaluate the Efficacy and Safety of CC-90001 in Participants With Non-alcoholic Steatohepatitis (NASH) and Liver Fibrosis [Phase 2]
A Phase 2 clinical trial evaluating CC-90001 for non-alcoholic fatty liver disease and liver cirrhosis was terminated; results were posted i…
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CLINICAL_TRIALS trial_result · 2023-05-24Clinical Trial Update: Efficacy of the Combination of Simvastatin Plus Rifaximin in Patients With Decompensated Cirrhosis to Prevent ACLF Development [Phase 2, Phase 3]
A Phase 2/3 trial evaluated simvastatin plus rifaximin in decompensated cirrhosis to prevent acute-on-chronic liver failure (ACLF).
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CLINICAL_TRIALS trial_result · 2023-05-23Clinical Trial Update: Phlebotomy and Lifestyle and Diet Advices vs Lifestyle and Diet Advices Only in Patients With Dysmetabolic Liversiderosis [Phase 3]
Phase 3 trial comparing phlebotomy plus lifestyle and diet advice versus lifestyle and diet advice alone in patients with dysmetabolic liver…
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CLINICAL_TRIALS trial_result · 2023-05-03Clinical Trial Update: Growth Hormone Therapy in Liver Cirrhosis [Phase 2, Phase 3]
Clinical trial update on Growth Hormone Therapy for liver cirrhosis (Phase 2/Phase 3) has been completed.
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CLINICAL_TRIALS trial_result · 2023-04-13Clinical Trial Update: Allopurinol Versus Atorvastatin to Prevent Complications of Liver Cirrhosis [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial comparing allopurinol to atorvastatin for preventing complications in liver cirrhosis and hepatic encephalo…
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CLINICAL_TRIALS trial_result · 2023-04-11Clinical Trial Update: Polidocanol Foam in Hemorrhoidal Disease in Patients With Liver Cirrhosis [Phase 2, Phase 3]
A clinical trial update for polidocanol foam in hemorrhoidal disease in patients with liver cirrhosis, spanning Phase 2 and Phase 3.
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CLINICAL_TRIALS trial_result · 2023-04-10Clinical Trial Update: A Phase II Open-label Single-arm Study to Evaluate the Efficacy and Safety of ADSCs in Subjects With Liver Cirrhosis [Phase 2]
Phase II open-label single-arm study assessing adipose-derived stem cells (ADSCs) for efficacy and safety in liver cirrhosis.
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CLINICAL_TRIALS trial_result · 2023-03-09Clinical Trial Update: Phase 4 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cholangitis [Phase 4]
Phase 4 trial of obeticholic acid in primary biliary cholangitis was terminated; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-01-13Clinical Trial Update: Statins for Prevention of Disease Progression and Hospitalization in Liver Cirrhosis [Phase 4]
Phase 4 trial update on statins for prevention of disease progression and hospitalization in liver cirrhosis; the study is terminated.
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CLINICAL_TRIALS trial_result · 2022-12-07Clinical Trial Update: Research on Optimal Strategy of Hypoglycemic Therapy for Cirrhosis With Diabetes [Phase 3]
Phase 3 trial investigating optimal hypoglycemic therapy strategy in patients with liver cirrhosis and diabetes; status not yet determined.
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CLINICAL_TRIALS trial_result · 2022-10-07Clinical Trial Update: Relationship Between Serum Vitamin D and Outcomes of Liver Transplantation in Cirrhotic Patients Undergoing Liver Transplantation and Effects of Vitamin D Supplementation in Post-transplant Period [Phase 1, Phase 2]
A mixed Phase 1/2 clinical trial evaluating the relationship between serum vitamin D and outcomes after liver transplantation in cirrhotic p…
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CLINICAL_TRIALS trial_result · 2022-09-27Clinical Trial Update: Effect of Probiotics in Non-alcoholic Fatty Liver Disease and Steatohepatitis [Phase 1, Phase 2]
A terminated Phase 1/2 clinical trial evaluating probiotics for non-alcoholic fatty liver disease and steatohepatitis; results have been pos…
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CLINICAL_TRIALS trial_result · 2022-09-06Clinical Trial Update: Study of Obeticholic Acid (OCA) Evaluating Pharmacokinetics and Safety in Participants With Primary Biliary Cholangitis (PBC) and Hepatic Impairment [Phase 4]
A Phase 4 clinical trial studying the pharmacokinetics and safety of obeticholic acid in participants with primary biliary cholangitis and h…
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CLINICAL_TRIALS trial_result · 2022-08-31Clinical Trial Update: Prophylactic Antibiotics in Admitted Cirrhotics [Phase 4]
Phase 4 trial update on prophylactic antibiotics in admitted cirrhotics; completed with posted results.
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CLINICAL_TRIALS trial_result · 2022-08-01Clinical Trial Update: Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1) [NA]
Completed pragmatic trial evaluating methods to improve communication about serious illness; results have been posted (2022-08-01).
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CLINICAL_TRIALS trial_result · 2022-07-27Clinical Trial Update: Granulocyte-Colony Stimulating Factor (G-CSF) as Optimizing Therapy for Pediatric Liver Transplantation [Phase 3]
A Phase 3 trial evaluating granulocyte-colony stimulating factor as an optimizing therapy for pediatric liver transplantation has been compl…
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CLINICAL_TRIALS trial_result · 2022-04-20Clinical Trial Update: Study to Investigate the Efficacy and Safety of Sofosbuvir/Velpatasvir Fixed-Dose Combination for 12 Weeks in Adults With Chronic HCV Infection and Compensated Cirrhosis [Phase 3]
Phase 3 trial evaluating Sofosbuvir/Velpatasvir fixed-dose combination for 12 weeks in adults with chronic Hepatitis C infection and compens…
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CLINICAL_TRIALS trial_result · 2022-02-02Clinical Trial Update: Rollover Study of Cenicriviroc for the Treatment of Liver Fibrosis in Participants With Nonalcoholic Steatohepatitis [Phase 2]
Phase 2 rollover study of cenicriviroc for liver fibrosis in nonalcoholic steatohepatitis was terminated; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-01-19Clinical Trial Update: Study to Assess Safety and Efficacy of Ifetroban for Treatment of Portal Hypertension in Cirrhotic Patients [Phase 2]
Phase 2 clinical trial assessing safety and efficacy of Ifetroban for portal hypertension in cirrhotic patients has completed with results p…
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CLINICAL_TRIALS trial_result · 2021-11-19Clinical Trial Update: Integrated Traditional Chinese and Clinical Medicine for Chronic Hepatitis B and Its Complication [Phase 3]
A Phase 3 clinical trial evaluating integrated traditional Chinese and clinical medicine for chronic hepatitis B and its complications is un…
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CLINICAL_TRIALS trial_result · 2021-10-12Clinical Trial Update: Carbamazepine in Severe Liver Disease Due to Alpha-1 Antitrypsin Deficiency [Phase 2]
Phase 2 trial investigating carbamazepine for severe liver disease due to Alpha-1 antitrypsin deficiency was terminated; results posted late…
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CLINICAL_TRIALS trial_result · 2021-08-26Clinical Trial Update: Anticoagulation Therapy After Splenectomy in Cirrhosis Patient [Phase 1, Phase 2]
A clinical trial evaluating anticoagulation therapy after splenectomy in patients with liver cirrhosis and portal hypertension has completed…
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CLINICAL_TRIALS trial_result · 2021-06-09Clinical Trial Update: PPIs and Gastroesophageal Varices in Liver Cirrhosis (PPIs: Proton Pump Inhibitors) [Phase 4]
Phase 4 trial update on proton pump inhibitors for patients with liver cirrhosis, hypertension, and portal conditions; results posted.
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CLINICAL_TRIALS trial_result · 2021-04-28Clinical Trial Update: Effect of Entecavir Treatment on Regression and Disease Outcome in HBV-induced Liver Fibrosis and Cirrhosis Patients [Phase 4]
Phase 4 trial assessing the impact of entecavir on regression and outcomes in patients with HBV-related liver fibrosis and cirrhosis.
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CLINICAL_TRIALS trial_result · 2021-03-17Clinical Trial Update: Mesenchymal Stem Cell Therapy for Liver Cirrhosis [Phase 1, Phase 2]
A clinical trial update on mesenchymal stem cell therapy for liver cirrhosis across Phase 1 and Phase 2.