Liver Cirrhosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: EUS-guided Versus Percutaneous Ultrasound-guided Biopsy for Parenchymal Liver Disease [NA]
A completed clinical trial comparing EUS-guided biopsy with percutaneous ultrasound-guided biopsy for parenchymal liver disease (liver cirrh…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Long Term Follow up Mesenchymal Stem Cell Therapy for Patients Virus-related Liver Cirrhosis [Phase 3]
A Phase 3 long-term follow-up study of mesenchymal stem cell therapy for virus-related liver cirrhosis has completed.
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: Growth Hormone in Decompensated Liver Cirrhosis [Phase 2, Phase 3]
Clinical trial update showing completion of Phase 2 and Phase 3 studies evaluating Growth Hormone in patients with decompensated liver cirrh…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Terlipressin in Combined Hepatorenal Syndrome in Patients With Signs of Chronic Renal Disease
Terlipressin was studied in a completed trial for combined hepatorenal syndrome in patients with signs of chronic kidney disease.
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: A Study to Investigate the Blood Concentrations of 4 Different Oral Doses of Zibotentan in Healthy Non-Asian and Japanese Participants [Phase 1]
A Phase 1 pharmacokinetic study evaluating blood concentrations after four oral doses of zibotentan in healthy non-Asian and Japanese partic…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Concordance Between Echocardiographic Assessment Performed in the Initial Phase of Decompensated Cirrhosis With Edema and Ascites by an Expert Intensive Care Physician and a Non-expert Gastroenterologist
This clinical trial update evaluates concordance between echocardiographic assessments performed by an expert intensive care physician and a…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Comparison of 24-hours Versus 72-hours of Octreotide Infusion in Preventing Early Rebleed From Esophageal Varices [Phase 4]
Phase 4 trial comparing 24-hour versus 72-hour octreotide infusion to prevent early rebleeding from esophageal varices in patients with live…
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CLINICAL_TRIALS trial_result · 2025-10-21Clinical Trial Update: A Phase 2, Safety and Efficacy of Bemnifosbuvir (BEM) and Ruzasvir (RZR) in Subjects With Chronic HCV [Phase 2]
Phase 2 results assess the safety and efficacy of Bemnifosbuvir and Ruzasvir in adults with chronic hepatitis C, including patients with liv…
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Short Term Outcomes in Hospitalized Patients With Liver Cirrhosis
A completed clinical trial sponsored by Assiut University evaluating short-term outcomes in hospitalized patients with liver cirrhosis.
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Improvement of Portal Hypertension During Viral Suppression in Patients With Hepatitis Delta (IMPHROVE-D)
The IMPHROVE-D trial reports improvement of portal hypertension in patients with hepatitis D during viral suppression; the study is active b…
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: A Study to Compare How Different Substances (Caffeine, Warfarin, Omeprazole, Metoprolol, and Midazolam) Are Handled by the Body of Healthy People and People With Liver Cirrhosis [NA]
A completed clinical trial comparing how five substances — caffeine, warfarin, omeprazole, metoprolol, and midazolam — are processed in heal…
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: Zibotentan and Dapagliflozin Combination, EvAluated in Liver Cirrhosis (ZEAL Study) [Phase 2]
The ZEAL Phase 2 trial evaluating the combination of Zibotentan and Dapagliflozin for liver cirrhosis has been terminated.
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CLINICAL_TRIALS trial_result · 2025-08-03Clinical Trial Update: Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes
A completed Indian clinical trial investigates whether combining gene variants can improve risk prediction for metabolic dysfunction-associa…
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Treatment of Sarcopenia Improves the Muscle Mass and Muscle Strength of Patients With Liver Cirrhosis-Child C [Phase 3]
A Phase 3 clinical trial update in patients with liver cirrhosis and sarcopenia reports improved muscle mass and muscle strength with the tr…
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CLINICAL_TRIALS trial_result · 2025-06-19Clinical Trial Update: EJV Occlusion Pressure Measurement to Assess Intravascular Volume in Cirrhotic Patients During IV Albumin Substitution [NA]
A completed clinical trial evaluating the use of external jugular vein occlusion pressure as a measure of intravascular volume during intrav…
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CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: A Study to Test Whether Two Different Doses of Avenciguat Help People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver) [Phase 2]
Phase 2 study evaluating two doses of Avenciguat in people with liver cirrhosis and portal hypertension has been terminated, with results po…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: A Study to Test Whether Avenciguat Helps People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver) Who Had Bleeding in the Esophagus or Fluid Accumulation in the Belly [Phase 2]
A Phase 2 trial evaluating Avenciguat in patients with liver cirrhosis and portal hypertension who had esophageal bleeding or ascites was te…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: International Study of High-Risk Patients for Hepatocellular Carcinoma Using Liquid Biopsy
A Johns Hopkins University–sponsored international trial evaluating liquid biopsy to detect hepatocellular carcinoma in high-risk patients w…
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: Contrast-Enhanced Ultrasound Imaging in Diagnosing Liver Cancer in Patients With Cirrhosis [NA]
A completed clinical trial evaluating contrast-enhanced ultrasound imaging for diagnosing hepatocellular carcinoma in patients with liver ci…
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CLINICAL_TRIALS trial_result · 2025-05-06Clinical Trial Update: Web-based Mobile Health Application for Patients With Liver Cirrhosis (ReLiver-N App) [NA]
This document reports the completion of a clinical trial evaluating a web-based mobile health application (ReLiver-N App) for patients with …
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: A Study to Test Whether BI 685509 Alone or in Combination With Empagliflozin Helps People With Liver Cirrhosis Caused by Viral Hepatitis or Non-alcoholic Steatohepatitis (NASH) Who Have High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver) [Phase 2]
A Phase 2 study evaluating BI 685509 alone or with empagliflozin for liver cirrhosis due to viral hepatitis or non-alcoholic steatohepatitis…
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: Stop of Proton-pump Inhibitor Treatment in Patients With Liver Cirrhosis - a Double-blind, Placebo-controlled Trial [Phase 4]
This clinical trial update describes stopping proton-pump inhibitor treatment in patients with liver cirrhosis within a double-blind, placeb…
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CLINICAL_TRIALS trial_result · 2025-04-15Clinical Trial Update: Simvastatin in Preventing Liver Cancer in Patients With Liver Cirrhosis [Phase 2]
Phase 2 trial evaluating simvastatin to prevent hepatocellular carcinoma in patients with liver cirrhosis; results have been posted and the …
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CLINICAL_TRIALS trial_result · 2025-04-01Clinical Trial Update: Using Data-Driven Implementation Strategies to Improve the Quality of Cirrhosis Care [NA]
This clinical trial update reports results of a data-driven implementation strategy designed to improve the quality of care for liver cirrho…
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Impact of Home-Based Aerobic and Resistance Training in Chronic Liver Disease: a Randomized Control Trial [NA]
A completed randomized controlled trial evaluating the effects of home-based aerobic and resistance training in individuals with chronic liv…