Liver Cirrhosis
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Predictors of Decompensation, Acute-on-chronic Liver Failure and Mortality in Liver Cirrhosis
A clinical trial update describing a study on predictors of decompensation, acute-on-chronic liver failure and mortality in liver cirrhosis,…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Umbilical Cord Mesenchymal Stem Cell for Liver Cirrhosis Patient Caused by Hepatitis B [Phase 1, Phase 2]
This entry reports a Phase 1/2 clinical trial using umbilical cord mesenchymal stem cells to treat liver cirrhosis caused by chronic hepatit…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Serosurvey of HAV Immunity and Single-dose Vaccine Immunogenicity Among Patients With Cirrhosis
This clinical trial evaluates hepatitis A immunity and the immunogenicity of a single-dose HAV vaccine in patients with cirrhosis; the study…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Direct Oral Anticoagulants (Rivaroxaban and Apixaban) in Patients With Liver Cirrhosis [Phase 1]
Ongoing Phase 1 clinical trial evaluating direct oral anticoagulants rivaroxaban and apixaban in patients with liver cirrhosis (recruiting).
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: A PROspective Faecal MIcrobiota tranSplantation Trial to Improve outcomEs in Patients With Cirrhosis [Phase 3]
A Phase 3 trial evaluating fecal microbiota transplantation to improve outcomes in liver cirrhosis is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Examining the Effects of Different Resistive Exercise Programs in Individuals With Compensated Liver Cirrhosis [NA]
A clinical trial update from Bahçeşehir University notes a study examining the effects of different resistive exercise programs in individua…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Portal Vein Thrombosis in Cirrhosis: Incidence, Outcomes and Anticoagulation
This clinical trial registry entry investigates the incidence and outcomes of portal vein thrombosis in liver cirrhosis and the role of anti…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: The Phase 1, Open-label, PET Trial Designed to Investigate the Effect of AZD2389 on FAP Occupancy in the Liver in Participants With Advanced Liver Fibrosis. [Phase 1]
Phase 1 open-label PET study to evaluate AZD2389 FAP occupancy in the liver of participants with advanced liver fibrosis. The trial is curre…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Cirrhotic and Non-cirrhotic Patients With Clinically Significant Portal Hypertension
The clinical trial update describes a study evaluating cirrhotic and non-cirrhotic patients with clinically significant portal hypertension …
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Mechanism of TIPS to Improve Sarcopenia
A clinical trial is examining whether a transjugular intrahepatic portosystemic shunt (TIPS) can improve sarcopenia. The study is currently …
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: ALTA TIPS: A 5-year Longitudinal Observational Study of Patients Undergoing TIPS Placement
This entry describes the ALTA TIPS study, a 5-year longitudinal observational study of patients undergoing transjugular intrahepatic portosy…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Effects of Empagliflozin on Fibrosis and Cirrhosis in Chronic Hepatitis B Patients [Phase 4]
Phase 4 clinical trial update on empagliflozin for liver fibrosis and cirrhosis in chronic hepatitis B with NAFLD; currently active but not …
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Study in Patients With Decompensated Liver Cirrhosis
An update on a clinical trial evaluating a treatment for decompensated liver cirrhosis sponsored by Resolution Therapeutics Limited; the stu…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: RTX001 Autologous Engineered Macrophages for Liver Cirrhosis [Phase 1, Phase 2]
RTX001 is an autologous engineered macrophage therapy being investigated in Phase 1/2 trials for end-stage liver disease and liver cirrhosis…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Using Autologous Bone Marrow Cells With Wharton Gel Exosomes to Stimulate Hepatic Cell Repair in Liver Cirrhosis [NA]
A clinical trial is investigating autologous bone marrow cells combined with Wharton gel exosomes to promote hepatic cell repair in liver ci…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Carvedilol vs. Propranolol for Preventing Rebleeding After Endoscopic Treatment of Cirrhotic Varices [Phase 4]
Phase 4 clinical trial comparing carvedilol to propranolol to prevent rebleeding after endoscopic treatment of cirrhotic varices in patients…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: TACE Combined With Tislelizumab, Lenvatinib, and Carvedilol for Unresectable HCC With Cirrhotic Portal Hypertension [Phase 2]
Phase 2 clinical trial evaluating transarterial chemoembolization plus tislelizumab, lenvatinib, and carvedilol for unresectable hepatocellu…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Underdilated-stent Technique Improves Post-TIPS Encephalopathy [NA]
A clinical trial update shows recruitment for a study evaluating an underdilated-stent technique to improve post-TIPS hepatic encephalopathy…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Effect of HFNC on Incidence of Hypoxia During Sedated Gastrointestinal Endoscopy in Critical Patients [NA]
A clinical trial evaluating whether high-flow nasal cannula reduces hypoxia during sedated gastrointestinal endoscopy in critically ill pati…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Diagnosis of Lymphohistiocytic Hemophagocytosis in Intensive Care
A clinical trial at University Hospital Strasbourg is evaluating diagnostic approaches for hemophagocytic lymphohistiocytosis in intensive c…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: naVIGation Invitations Liver surveillANce upTake
Imperial College London reports an updated clinical trial investigating uptake of liver surveillance in patients with hepatocellular carcino…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Effect of Handgrip Strength on Portal Vein Hemodynamics in Patients With Liver Cirrhosis [NA]
A clinical trial is evaluating whether handgrip strength influences portal vein hemodynamics in patients with liver cirrhosis and portal hyp…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Study of Tremelimumab and Durvalumab (MEDI4736) (T300+D) in Advanced Hepatocellular Carcinomas With Child-Pugh-B Cirrhosis [Phase 2]
A Phase 2 clinical trial evaluating the combination of tremelimumab and durvalumab in advanced hepatocellular carcinoma patients with Child-…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Verification of Risk Factors of Thrombohemorrhagic Complications in Recipients After Related Liver Transplantation
A clinical trial is investigating risk factors for thrombohemorrhagic complications in recipients after related liver transplantation.
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Evaluating the Efficacy of Vonoprazan in Preventing Post-Endoscopic Variceal Band Ligation Ulcers: A Randomized Controlled Trial [Phase 2]
A Phase 2 randomized trial evaluating whether vonoprazan can prevent ulcers after endoscopic variceal band ligation in patients with liver c…