Liposarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) [Phase 1, Phase 2]
This is a clinical trial protocol update for NRSTS2021, a Phase 1/2 study evaluating maintenance pazopanib, limited-margin radiation therapy…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Testing Ipilimumab and Nivolumab Combination With or Without Cabozantinib in People >= 18 Years Old With Advanced Soft Tissue Sarcoma [Phase 2]
A Phase 2 clinical trial update describes testing the combination of ipilimumab and nivolumab with or without cabozantinib in adults with ad…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Talimogene Laherparepvec and Radiation Therapy in Treating Patients With Newly Diagnosed Soft Tissue Sarcoma That Can Be Removed by Surgery [Phase 2]
Clinical trial update for a Phase 2 study evaluating Talimogene laherparepvec with radiation therapy in newly diagnosed soft tissue sarcoma …
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors [Phase 1, Phase 2]
Clinical trial evaluating silmitasertib (CX-4945) in combination with chemotherapy for relapsed or refractory solid tumors; Phase 1 and Phas…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors [Phase 1]
Phase 1 trial evaluating an IL-15/IL-21 armored GPC3-targeted CAR-T cell therapy for pediatric solid tumors is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma [Phase 3]
A Phase 3 clinical trial is evaluating whether adding neoadjuvant chemotherapy to surgery improves outcomes for high-risk retroperitoneal sa…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Evaluation of Abemaciclib and Radiation Therapy Before Surgery for the Treatment of High-Risk Adipocytic Retroperitoneal Sarcoma [Phase 1]
Phase 1 trial evaluating the combination of abemaciclib with radiation therapy before surgical resection in patients with high-risk adipocyt…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Precision Medicine Approaches for Neoadjuvant Therapy in High-risk Sarcoma Patients
Clinical trial update describing precision medicine approaches for neoadjuvant therapy in high‑risk sarcoma patients; currently recruiting.
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells [Phase 1]
Phase 1 pediatric trial of interleukin-15 and interleukin-21 armored glypican-3–specific CAR T cells for solid tumors, including liver-origi…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Dose-escalated, Hypofractionated, Definitive Proton Radiotherapy for Patients With Inoperable Soft Tissue Sarcoma. [Phase 2]
Clinical trial evaluating dose-escalated, hypofractionated definitive proton radiotherapy for patients with inoperable soft tissue sarcoma (…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Hypofractionated, 3-week, Preoperative Proton or X-ray Radiotherapy for Patients With Localized Soft Tissue Sarcoma [Phase 2]
Phase 2 clinical trial update evaluating hypofractionated, 3-week preoperative radiotherapy using proton or photon therapy for localized sof…
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CLINICAL_TRIALS research · 2025-11-03Clinical Trial Update: Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells [Phase 1]
Phase 1 clinical trial evaluating GPC3-targeted CAR T cells armored with IL-15 and IL-21 for GPC3-positive solid tumors; currently recruitin…
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: BTX-A51 in Patients With Liposarcoma or CIC-rearranged Sarcoma [Phase 1]
This ClinicalTrials.gov update reports that a Phase 1 study of BTX-A51 is currently recruiting for liposarcoma and CIC-rearranged sarcoma, i…
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CLINICAL_TRIALS research · 2025-10-24Clinical Trial Update: Zanzalintinib Combined With Eribulin in Advanced Liposarcoma and Leiomyosarcoma [Phase 1]
Phase 1 clinical trial evaluating the combination of zanzalintinib and eribulin in patients with advanced liposarcoma and leiomyosarcoma; re…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors [Phase 2]
Phase 2 study to assess safety and tolerability of PF-07220060 in adults with advanced solid tumors; the trial is currently ACTIVE_NOT_RECRU…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma [Phase 2]
A Phase 2 trial evaluating MASCT-I in combination with doxorubicin and ifosfamide as first-line therapy for advanced soft tissue sarcoma is …
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: Multicohort Trial of Different Schemes of PM14 in Monotherapy and in Combination with Radiotherapy in Soft Tissue Sarcomas and Other Solid Tumor [Phase 1, Phase 2]
Multicohort Phase 1/2 clinical trial evaluating PM14 as monotherapy and in combination with radiotherapy for soft tissue sarcoma and other s…
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CLINICAL_TRIALS research · 2025-02-26Clinical Trial Update: APG-115 in Combination With PD-1 Inhibitor in Patients With Advanced Liposarcoma or Advanced Solid Tumors [Phase 1, Phase 2]
Clinical trial update describing an ongoing Phase 1/2 study of APG-115 in combination with a PD-1 inhibitor for patients with liposarcoma or…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas [NA]
A clinical trial update describes the identification of a new blood biomarker for diagnosing liposarcoma and atypical lipomatous tumor and f…
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CLINICAL_TRIALS research · 2018-07-02Clinical Trial Update: Detection of Circulating Tumor Cells in Patients With Sarcomas
An update on a clinical trial investigating detection of circulating tumor cells in patients with sarcomas, including Leiomyosarcoma, Pleomo…
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CLINICAL_TRIALS research · 2016-11-23Clinical Trial Update: A Phase II Study Assessing Efficacy & Safety of Ribociclib in Patients With Advanced Well/Dedifferentiated Liposarcoma [Phase 2]
Phase II clinical trial evaluating the efficacy and safety of ribociclib in patients with advanced well-differentiated or dedifferentiated l…
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CLINICAL_TRIALS research · 2016-05-17Clinical Trial Update: Studying Genes in Tissue Samples From Younger and Adolescent Patients With Soft Tissue Sarcomas
A completed clinical trial update studying gene expression in tissue samples from children and adolescents with soft tissue sarcomas to bett…