Lipoprotein Lipase Deficiency
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Postprandial Fatty Acid Metabolism in Subjects With Lipoprotein Lipase Deficiency [NA]
A clinical trial update indicates a study on postprandial fatty acid metabolism in individuals with lipoprotein lipase deficiency is current…
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CLINICAL_TRIALS trial_result · 2021-08-26Clinical Trial Update: The Approach Open Label Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Chylomicronemia Syndrome [Phase 3]
Phase 3 open-label study of volanesorsen in familial chylomicronemia syndrome has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-01-07Clinical Trial Update: Phase 2 Study of AKCEA-ANGPTL3-LRx (ISIS 703802) in Participants With Familial Chylomicronemia Syndrome (FCS) [Phase 2]
Phase 2 trial update for AKCEA-ANGPTL3-LRx (ISIS 703802) in Familial Chylomicronemia Syndrome (and related lipoprotein lipase deficiency) ha…
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CLINICAL_TRIALS withdrawal · 2017-08-17Clinical Trial Update: Alipogene Tiparvovec for the Treatment of LPLD Patients [Phase 2]
A Phase 2 trial of alipogene tiparvovec for lipoprotein lipase deficiency was withdrawn from the study.
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EMA withdrawal · 2012-04-20European Medicines Agency maintains recommendation not to grant a marketing authorisation for Glybera
The European Medicines Agency maintains its recommendation not to grant marketing authorisation for Glybera (alipogene mimutran) for lipopro…
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CLINICAL_TRIALS trial_result · 2011-10-07Clinical Trial Update: Study to Re-assess and Re-confirm Data Previously Recorded About the Incidence and Severity of Acute Abdominal "Pancreatitis" Episodes in Lipoprotein Lipase Deficient (LPLD) Subjects Previously Enrolled on AMT Clinical Studies
A clinical trial update from Amsterdam Molecular Therapeutics to re-assess and re-confirm data on the incidence and severity of acute pancre…
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CLINICAL_TRIALS trial_result · 2011-09-29Clinical Trial Update: Efficacy and Safety of Human Lipoprotein Lipase (LPL)[S447X] Expressed by an Adeno-Associated Viral Vector in LPL-deficient Subjects [Phase 2, Phase 3]
Completed Phase 2/3 trial evaluating the efficacy and safety of LPL S447X gene therapy expressed by an adeno-associated viral vector in indi…