Light-chain Amyloidosis

• CLINICAL_TRIALS research · 2026-04-21
  Clinical Trial Update: A Phase II Trial of Teclistamab in Participants With Previously Treated Immunoglobulin Light-chain (AL) Amyloidosis [Phase 2]

  A Phase II clinical trial is evaluating teclistamab in previously treated light-chain (AL) amyloidosis and is currently recruiting.

• CLINICAL_TRIALS research · 2026-03-24
  Clinical Trial Update: A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis. [Phase 1, Phase 2]

  Phase 1b/2 study of a dual-target CD19/BCMA CAR T cell therapy for relapsed or refractory light-chain (AL) amyloidosis is currently recruiti…

• CLINICAL_TRIALS research · 2025-11-26
  Clinical Trial Update: Study Evaluating the Efficacy and Safety of CM336 Injection in the Treatment of Light-Chain Amyloidosis [Phase 2]

  This entry reports a Phase 2 clinical trial evaluating the efficacy and safety of CM336 Injection for primary light-chain amyloidosis, curre…

• CLINICAL_TRIALS research · 2025-10-10
  Clinical Trial Update: A Clinical Study on Minimal Residual Disease in Patients With Systemic Light Chain Amyloidosis [NA]

  A clinical trial investigating minimal residual disease in patients with systemic light-chain (AL) amyloidosis, sponsored by Peking Universi…

• CLINICAL_TRIALS research · 2025-06-03
  Clinical Trial Update: Daratumumab Combined With Venetoclax and Dexamethasone for Newly Diagnosed Light-Chain Amyloidosis With Translocation (11;14) [Phase 2]

  Phase 2 clinical trial evaluating a combination of daratumumab, venetoclax, and dexamethasone for newly diagnosed light-chain amyloidosis wi…

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• CLINICAL_TRIALS research · 2025-05-21
  Clinical Trial Update: Exploratory Clinical Study on the Safety and Efficacy of Targeted BCMA Autologous CART Cell Injection in Subjects With Recurrent/Refractory Light Chain Amyloidosis [NA]

  An exploratory clinical study is evaluating the safety and potential efficacy of BCMA-targeted autologous CAR T cell injections in patients …

• CLINICAL_TRIALS research · 2025-05-14
  Clinical Trial Update: Study of HBI0101 (NXC-201) CAR-T Therapy in Multiple Myeloma and Light-Chain Amyloidosis [Phase 2]

  This phase 2 study is evaluating the CAR-T therapy HBI0101 (NXC-201) in patients with multiple myeloma (refractory or relapsed) and light-ch…

• CLINICAL_TRIALS research · 2025-01-22
  Clinical Trial Update: Venetoclax and Dexamethasone for Newly Diagnosed Light-Chain Amyloidosis with Translocation (11;14) [Phase 2]

  Phase 2 trial of venetoclax plus dexamethasone for newly diagnosed light-chain (AL) amyloidosis with t(11;14) translocation; currently activ…