Leprosy
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Accuracy of the Polymerase Chain Reaction of Ulnar Perineural Subcutaneous Aspirate Guided by Ultrasound for the Diagnosis and Monitoring of Leprosy Cure [NA]
This clinical trial update reports on evaluating the accuracy of ultrasound-guided PCR of ulnar perineural aspirates for diagnosing and moni…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Potential Injection of Human Umbilical Cord Secretome in the Case of Trophic Ulcers (Pre-post Intervention) [Phase 1]
Phase 1 trial evaluating injection of human umbilical cord secretome for trophic ulcers in leprosy patients has completed.
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Early Detection and AI-Based Management of Skin-Related Neglected Tropical Diseases in Sub-Saharan Africa by Frontline Health Workers [NA]
An update on a Kenya Medical Research Institute clinical trial aiming to detect and manage skin-related neglected tropical diseases in Sub-S…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Epidemiological, Clinical, Diagnostic, and Therapeutic Characteristics of Hansen's Disease in Costa Rica (2018-2025)
This clinical trial update seeks to describe the epidemiology, clinical features, diagnostic methods, and treatment characteristics of Hanse…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Efficacy and Safety Study of Dovramilast in People With Leprosy Type 2 Reaction [Phase 2]
A Phase 2 clinical trial evaluating the efficacy and safety of dovramilast in people with erythema nodosum leprosum (leprosy type 2 reaction…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Integrating Mental Health Into Neglected Tropical Disease Care in Ghana [NA]
This clinical trial update notes efforts to integrate mental health services into neglected tropical disease care in Ghana. No specific drug…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Novel Interventions and Diagnostic Tests for Leprosy [NA]
The entry reports that a study led by Annemieke Geluk is recruiting participants to evaluate novel interventions and diagnostic tests for le…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: Efficacy and Tolerability of Adjunct Metformin for Multibacillary Leprosy [Phase 2]
An ongoing Phase 2 trial is evaluating the efficacy and tolerability of adding metformin to standard therapy for multibacillary leprosy.
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Leprosy Active Searching Trial in Brazil [NA]
A Brazil-based clinical trial sponsored by Hospital Alemão Oswaldo Cruz is actively recruiting to study leprosy through active case searchin…
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FDA approval · 2025-06-17FDA Approved: DAPSONE — Supplemental Application (Torrent Pharmaceuticals Limited)
FDA approved a supplemental application for DAPSONE submitted by Torrent Pharmaceuticals Limited.
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FDA approval · 2025-04-23FDA Approved: DAPSONE — Supplemental Application (Seton Pharmaceuticals)
FDA approved a supplemental application for DAPSONE tablets from Seton Pharmaceuticals.
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FDA approval · 2025-04-04FDA Approved: DAPSONE — Original Application (Aurobindo Pharma Limited)
The FDA approved Aurobindo Pharma Limited's Original Abbreviated New Drug Application for DAPSONE (dapsone), a generic antibiotic used for d…
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CLINICAL_TRIALS trial_result · 2025-03-04Clinical Trial Update: Post ExpOsure Prophylaxis for LEprosy in the Comoros and Madagascar [Phase 3]
A Phase 3 post-exposure prophylaxis trial for leprosy in the Comoros and Madagascar has completed, with results posted.
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: Rab 32 Gene Polymorphisms as a Prognostic Factor in Leprosy Patients [NA]
A clinical trial is investigating whether Rab32 gene polymorphisms can serve as prognostic factors in patients with leprosy caused by Mycoba…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: TGF β 1 Expression Related Gene Polymorphism
Aswan University is recruiting for a study examining TGF-β1 expression-related gene polymorphisms in individuals with leprosy.
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CLINICAL_TRIALS trial_result · 2024-11-08Clinical Trial Update: Serum Irisin Level In Leprosy Patients
The document notes the completion of a clinical trial evaluating serum irisin levels in patients with leprosy.
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CLINICAL_TRIALS research · 2024-10-04Clinical Trial Update: Trial LEP-F1 + GLA-SE in Healthy Adult in Areas Endemic for Leprosy [Phase 1]
Phase 1 clinical trial update evaluating LEP-F1 vaccine with GLA-SE adjuvant in healthy adults in leprosy-endemic areas; currently not recru…
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: Bedaquiline Enhanced Post ExpOsure Prophylaxis for Leprosy (Phase 2) [Phase 2]
Phase 2 study evaluating bedaquiline as enhanced post-exposure prophylaxis for leprosy has completed. Results were posted in August 2024.
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FDA approval · 2024-08-26FDA Approved: DAPSONE — Original Application (Trupharma, LLC)
FDA approves a generic version of dapsone (DAPSONE) under Original Application by Trupharma, LLC (ANDA213636).
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CLINICAL_TRIALS research · 2024-06-28Clinical Trial Update: Bedaquiline Enhanced Post ExpOsure Prophylaxis for Leprosy [Phase 3]
Phase 3 clinical trial evaluating bedaquiline-based enhanced post-exposure prophylaxis for leprosy is currently recruiting.
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CLINICAL_TRIALS research · 2024-06-10Clinical Trial Update: Integrated Mapping of Skin-presenting Neglected Tropical Diseases in Liberia
This clinical trial update describes an integrated mapping study to map skin-presenting neglected tropical diseases in Liberia, including le…
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FDA approval · 2024-05-08FDA Approved: DAPSONE — Original Application (Zydus Lifesciences Limited)
FDA approves DAPSONE from Zydus Lifesciences Limited as an Original Application, providing a generic dapsone product.
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CLINICAL_TRIALS trial_result · 2024-02-02Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Bedaquiline (TMC207) in Participants With Multibacillary Leprosy [Phase 2]
A Phase 2 study evaluated the efficacy and safety of bedaquiline (TMC207) in participants with multibacillary leprosy, with completed status…
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FDA approval · 2023-10-27FDA Approved: DAPSONE — Original Application (Alembic Pharmaceuticals Inc.)
FDA approved the original application for DAPSONE (dapsone) as a generic drug from Alembic Pharmaceuticals Inc.
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FDA approval · 2023-10-19FDA Approved: DAPSONE — Original Application (Amneal Pharmaceuticals LLC)
FDA approved the generic dapsone (DAPSONE) under Amneal Pharmaceuticals LLC's Original ANDA.