Leiomyosarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: IO Combined With AI as First-line Treatment for Patients With Soft Tissue Sarcoma(TAIS) [Phase 2]
Phase 2 trial evaluating an immuno-oncology combination as first-line treatment for soft tissue sarcomas; currently recruiting.
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Cabozantinib and Temozolomide for the Treatment of Unresectable or Metastatic Leiomyosarcoma or Other Soft Tissue Sarcoma [Phase 2]
Phase 2 clinical trial evaluating cabozantinib in combination with temozolomide for unresectable or metastatic leiomyosarcoma and other soft…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Metastatic Leiomyosarcoma Biomarker Protocol
This clinical trial update describes a biomarker-driven protocol for metastatic leiomyosarcoma being conducted by the University of Michigan…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: CytoreductiveSurgery & HIPEC w/Gemcitabine+Chemotherapy w/Dacarbazine in Uterine Leiomyosarcoma [Phase 2]
Phase 2 clinical trial update for cytoreductive surgery with HIPEC using gemcitabine and dacarbazine in uterine leiomyosarcoma; the study is…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: A Study of Rucaparib and Nivolumab in People With Leiomyosarcoma [Phase 2]
This clinical trial update describes a phase 2 study evaluating the combination of rucaparib and nivolumab in people with leiomyosarcoma, wi…
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CLINICAL_TRIALS research · 2025-10-24Clinical Trial Update: Zanzalintinib Combined With Eribulin in Advanced Liposarcoma and Leiomyosarcoma [Phase 1]
Phase 1 clinical trial evaluating the combination of zanzalintinib and eribulin in patients with advanced liposarcoma and leiomyosarcoma; re…
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Targeting ATR in Soft-tissue Sarcomas [Phase 2]
Phase 2 trial update evaluating an ATR-targeting therapy for adult leiomyosarcoma; recruitment is ongoing.
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Study of All-Trans Retinoic Acid (ATRA) and Cemiplimab in Patients With Advanced Leiomyosarcoma [Phase 2]
A Phase 2 trial evaluating the combination of all-trans retinoic acid (ATRA) and cemiplimab in advanced leiomyosarcoma is currently recruiti…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: AOH1996 for the Treatment of Refractory Solid Tumors [Phase 1]
AOH1996 is being studied in a Phase 1 trial for patients with refractory solid tumors, including osteosarcoma and several other sarcomas and…
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CLINICAL_TRIALS trial_result · 2025-08-28Clinical Trial Update: A Phase II Study of Eribulin and Pembrolizumab in Soft Tissue Sarcomas [Phase 2]
A Phase II study evaluating the combination of eribulin and pembrolizumab in soft tissue sarcomas has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2025-08-28Clinical Trial Update: Study of DCC-3014 in Combination With Avelumab in Patients With Advanced or Metastatic Sarcomas [Phase 1]
Phase 1 study of DCC-3014 in combination with Avelumab in patients with advanced or metastatic sarcoma has completed; no efficacy data is pr…
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: Treatment With Dinutuximab Beta, Zoledronic Acid and Low-dose Interleukin (IL-2) in Patients With Leiomyosarcoma [Phase 2]
Phase 2 clinical trial evaluating dinutuximab beta in combination with zoledronic acid and low-dose interleukin-2 in leiomyosarcoma has comp…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma [Phase 2]
A Phase 2 trial evaluating MASCT-I in combination with doxorubicin and ifosfamide as first-line therapy for advanced soft tissue sarcoma is …
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: A Study of Unesbulin in Participants With Advanced Leiomyosarcoma (LMS) [Phase 2, Phase 3]
A Phase 2/3 trial of Unesbulin in advanced leiomyosarcoma was terminated, with results posted on 2025-06-13.
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Beliefs, Attitudes, and Response to Genetic Testing in SarcomaPatients
A University of Utah study is investigating beliefs, attitudes, and responses to genetic testing among patients with leiomyosarcoma.
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Circulating " Cancer Cells / Macrophage " HYbrid Cells in Patients With Sarcoma, Part 2 [NA]
Clinical trial update on a study of circulating cancer cell/macrophage hybrid cells in patients with Leiomyosarcoma; the trial is currently …
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CLINICAL_TRIALS trial_result · 2025-05-29Clinical Trial Update: A Study of Different Dosing Schedules of Selinexor in Sarcoma Patients [Phase 1]
Phase 1 study evaluating different dosing schedules of Selinexor in soft tissue sarcoma and related tumors has completed.
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CLINICAL_TRIALS trial_result · 2025-04-04Clinical Trial Update: Phase II Trial of Ribociclib and Everolimus in Advanced Dedifferentiated Liposarcoma (DDL) and Leiomyosarcoma (LMS) [Phase 2]
Phase II clinical trial evaluating ribociclib in combination with everolimus in advanced dedifferentiated liposarcoma and leiomyosarcoma; th…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Metronomic Trabectedin, Gemcitabine, and Dacarbazine for Soft Tissue Sarcoma [Phase 2]
A Phase 2 clinical trial update evaluating metronomic dosing of a three-drug combination (trabectedin, gemcitabine, and dacarbazine) for lei…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: A Study of Nivolumab in Selected Uterine Cancer Patients [Phase 2]
Phase 2 study of Nivolumab in selected uterine cancers has completed enrollment and posted results in 2024.
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: Cytotoxic T Cells to Treat Relapsed EBV-positive Lymphoma [Phase 1]
Phase 1 trial testing EBV-specific cytotoxic T cells in relapsed EBV-positive lymphomas has completed, assessing safety and preliminary acti…
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CLINICAL_TRIALS trial_result · 2024-12-11Clinical Trial Update: A Study to Learn About the Study Medicine (Called Ontorpacept or TTI-621) Given Alone and in Combination With Doxorubicin in People With Leiomyosarcoma [Phase 2]
Pfizer's Phase 2 study of Ontorpacept (TTI-621) alone or with doxorubicin in leiomyosarcoma was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2024-11-25Clinical Trial Update: Lenvatinib and Eribulin in Advanced Soft Tissue Sarcoma [Phase 1, Phase 2]
Phase 1/2 study evaluating lenvatinib and eribulin in advanced soft tissue sarcoma has completed with posted results. The study includes lei…
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: Pazopanib Vs. Pazopanib Plus Gemcitabine [Phase 2]
A Phase 2 trial comparing pazopanib alone versus pazopanib plus gemcitabine for leiomyosarcoma or carcinosarcoma is currently active but not…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Itacitinib in Treating Patients With Refractory Metastatic/Advanced Sarcomas [Phase 1]
Itacitinib was studied in a Phase 1 trial for patients with refractory metastatic/advanced sarcomas, but the study status is TERMINATED.