Leiomyosarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-05-12Clinical Trial Update: Nivolumab Alone or in Combination With Ipilimumab in Treating Patients With Advanced Uterine Leiomyosarcoma [Phase 2]
Phase 2 clinical trial evaluating nivolumab alone or in combination with ipilimumab in patients with advanced or unresectable uterine leiomy…
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CLINICAL_TRIALS trial_result · 2020-01-31Clinical Trial Update: Efficacy of Gemcitabine With Pazopanib as Second Line Treatment in Patient With Metastatic or Relapsed Uterine [Phase 2]
Phase 2 trial evaluating gemcitabine with pazopanib as second-line therapy in metastatic or relapsed uterine leiomyosarcoma.
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CLINICAL_TRIALS trial_result · 2019-01-29Clinical Trial Update: SARC018: A Study of Mocetinostat and Gemcitabine in Patients With Metastatic Leiomyosarcoma [Phase 2]
Phase 2 study SARC018 evaluated mocetinostat in combination with gemcitabine for metastatic leiomyosarcoma; results were posted in 2019.
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CLINICAL_TRIALS trial_result · 2018-07-17Clinical Trial Update: A Five-Tier, Open-Label Study of IMC-A12 in Advanced Sarcoma [Phase 2]
Open-label Phase 2 study of IMC-A12 (cixutumumab) in advanced sarcomas. Results were posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-11Clinical Trial Update: A Study of Trabectedin (YONDELIS) in Patients With Locally Advanced or Metastatic Liposarcoma or Leiomyosarcoma [Phase 3]
This clinical trial update notes the completion of a Phase 3 study evaluating trabectedin (YONDELIS) in patients with locally advanced or me…
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CLINICAL_TRIALS trial_result · 2017-05-19Clinical Trial Update: Bevacizumab and Radiation Therapy for Sarcomas [Phase 2]
Phase 2 trial evaluating bevacizumab with radiation therapy in soft tissue sarcomas completed, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma [Phase 2]
Phase 2 clinical trial update for romidepsin (depsipeptide) in patients with metastatic or unresectable soft tissue sarcoma, with results po…
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CLINICAL_TRIALS trial_result · 2017-01-26Clinical Trial Update: Study of Doxorubicin and Trabectedin in First Line Treatment on Patients With Metastatic Leiomyosarcoma [Phase 2]
Phase 2 trial evaluating first-line Doxorubicin and Trabectedin in metastatic leiomyosarcoma has completed; results are not detailed in this…
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CLINICAL_TRIALS trial_result · 2016-12-28Clinical Trial Update: Alisertib in Treating Patients With Advanced or Metastatic Sarcoma [Phase 2]
A Phase 2 trial update of alisertib in patients with advanced or metastatic soft tissue sarcomas, including myxofibrosarcoma and several his…
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CLINICAL_TRIALS trial_result · 2016-05-17Clinical Trial Update: Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma [Phase 1]
This Phase 1 trial evaluated the combination of cixutumumab and doxorubicin in patients with unresectable, locally advanced, or metastatic s…
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CLINICAL_TRIALS trial_result · 2016-02-17Clinical Trial Update: Gemcitabine and Docetaxel in Combination With Pazopanib (Gem/Doce/Pzb) for the Neoadjuvant Treatment of Soft Tissue Sarcoma (STS) [Phase 1, Phase 2]
Phase 1/2 trial of gemcitabine and docetaxel with pazopanib for neoadjuvant treatment in soft tissue sarcoma was terminated; results posted …
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CLINICAL_TRIALS trial_result · 2016-01-28Clinical Trial Update: A Study of Trabectedin or Dacarbazine for the Treatment of Patients With Advanced Liposarcoma or Leiomyosarcoma [Phase 3]
A Phase 3 trial compared trabectedin to dacarbazine in patients with advanced liposarcoma or leiomyosarcoma; results were posted in January …
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CLINICAL_TRIALS trial_result · 2016-01-25Clinical Trial Update: Gemcitabine and Docetaxel With Bevacizumab in Selected Sarcoma Subtypes [Phase 2]
A Phase 2 trial evaluated the combination of gemcitabine, docetaxel, and bevacizumab in selected sarcoma subtypes, including leiomyosarcoma …
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CLINICAL_TRIALS trial_result · 2015-11-20Clinical Trial Update: Sorafenib and Dacarbazine in Soft Tissue Sarcoma [Phase 2]
A Phase 2 study evaluating the combination of sorafenib and dacarbazine in soft tissue sarcoma reported completed results in 2015, including…
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CLINICAL_TRIALS trial_result · 2015-07-30Clinical Trial Update: AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue Sarcoma [Phase 2]
A Phase 2 trial evaluating saracatinib (AZD0530) in adults with recurrent, locally advanced, or metastatic soft tissue sarcoma has completed…
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CLINICAL_TRIALS trial_result · 2015-02-13Clinical Trial Update: Study of AP23573/MK-8669 (Ridaforolimus), A Mammalian Target of Rapamycin (mTOR) Inhibitor, in Participants With Advanced Sarcoma (MK-8669-018 AM1)(COMPLETED) [Phase 2]
This update reports the completion of a Phase 2 trial of ridaforolimus (AP23573/MK-8669), an mTOR inhibitor, in patients with advanced sarco…
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CLINICAL_TRIALS trial_result · 2014-12-16Clinical Trial Update: Combination Therapy of Gemcitabine and Trabectedin in L-sarcomas [Phase 1]
Phase 1 trial evaluating the combination of gemcitabine and trabectedin in leiomyosarcoma and liposarcoma has completed. The study explored …
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CLINICAL_TRIALS trial_result · 2014-12-01Clinical Trial Update: Adjuvant Chemotherapy for High Risk Uterine Leiomyosarcoma [Phase 2]
Phase 2 adjuvant chemotherapy trial for high-risk uterine leiomyosarcoma has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2014-10-02Clinical Trial Update: Safety and Efficacy Study of REOLYSIN® in the Treatment of Bone and Soft Tissue Sarcomas Metastatic to the Lung [Phase 2]
Phase 2 study evaluating REOLYSIN (pelareorep) for bone and soft tissue sarcomas metastatic to the lung has been completed, assessing safety…
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CLINICAL_TRIALS trial_result · 2014-09-08Clinical Trial Update: A Study to Assess Treatment With 2 Different Dosing Schedules of Trabectidin Administered to Patients With Advanced Cancer [Phase 2]
This Phase 2 trial evaluated two dosing schedules of trabectedin in patients with advanced liposarcoma or leiomyosarcoma; the study has comp…
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CLINICAL_TRIALS trial_result · 2014-01-20Clinical Trial Update: Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent Sarcoma [Phase 2]
Phase 2 clinical trial evaluating sorafenib for metastatic, locally advanced, or recurrent sarcoma has completed and posted results in 2014.
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CLINICAL_TRIALS trial_result · 2014-01-06Clinical Trial Update: Temozolomide and Thalidomide in Treating Patients With Metastatic, Locally Advanced, or Unresectable Leiomyosarcoma [Phase 2]
A Phase 2 trial evaluating temozolomide with thalidomide in patients with metastatic, locally advanced, or unresectable leiomyosarcoma.
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CLINICAL_TRIALS trial_result · 2013-11-08Clinical Trial Update: S9624 Ifosfamide in Treating Patients With Meningeal Tumors [Phase 2]
Phase 2 SWOG trial of ifosfamide for meningeal tumors and related sarcomas was terminated.
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CLINICAL_TRIALS trial_result · 2013-03-07Clinical Trial Update: Gemcitabine, Docetaxel, and Filgrastim in Treating Patients With Recurrent or Persistent Leiomyosarcoma or Soft Tissue Sarcoma [Phase 2]
Phase 2 trial evaluating the combination of gemcitabine, docetaxel, and filgrastim in patients with recurrent or persistent leiomyosarcoma o…
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CLINICAL_TRIALS trial_result · 2012-08-28Clinical Trial Update: Phase II Study of Sunitinib Malate for Metastatic and/or Surgically Unresectable Soft Tissue Sarcoma [Phase 2]
Phase II trial results for sunitinib malate in metastatic or surgically unresectable soft tissue sarcoma were posted, evaluating activity ac…