Leiomyosarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: A Study to Evaluate Tabelecleucel in Participants With Epstein Barr Virus (EBV) Associated Diseases [Phase 2]
Phase 2 clinical trial evaluating tabelecleucel in EBV-associated diseases is active/not recruiting, focusing on EBV+ LPD and related condit…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma [Phase 1]
Phase 1 trial evaluating the safety of low-dose pegylated liposomal doxorubicin in combination with peposertib for advanced sarcoma; current…
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CLINICAL_TRIALS trial_result · 2026-02-13Clinical Trial Update: Pembrolizumab and Gemcitabine Chemotherapy in Leiomyosarcoma and Undifferentiated Pleomorphic Sarcoma [Phase 1, Phase 2]
This update reports the completion and posted results of a Phase 1/2 trial evaluating pembrolizumab in combination with gemcitabine chemothe…
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Targeting ATR in Soft-tissue Sarcomas [Phase 2]
Phase 2 trial update evaluating an ATR-targeting therapy for adult leiomyosarcoma; recruitment is ongoing.
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CLINICAL_TRIALS trial_result · 2025-08-28Clinical Trial Update: A Phase II Study of Eribulin and Pembrolizumab in Soft Tissue Sarcomas [Phase 2]
A Phase II study evaluating the combination of eribulin and pembrolizumab in soft tissue sarcomas has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2025-08-28Clinical Trial Update: Study of DCC-3014 in Combination With Avelumab in Patients With Advanced or Metastatic Sarcomas [Phase 1]
Phase 1 study of DCC-3014 in combination with Avelumab in patients with advanced or metastatic sarcoma has completed; no efficacy data is pr…
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: Treatment With Dinutuximab Beta, Zoledronic Acid and Low-dose Interleukin (IL-2) in Patients With Leiomyosarcoma [Phase 2]
Phase 2 clinical trial evaluating dinutuximab beta in combination with zoledronic acid and low-dose interleukin-2 in leiomyosarcoma has comp…
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: A Study of Unesbulin in Participants With Advanced Leiomyosarcoma (LMS) [Phase 2, Phase 3]
A Phase 2/3 trial of Unesbulin in advanced leiomyosarcoma was terminated, with results posted on 2025-06-13.
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CLINICAL_TRIALS trial_result · 2025-05-29Clinical Trial Update: A Study of Different Dosing Schedules of Selinexor in Sarcoma Patients [Phase 1]
Phase 1 study evaluating different dosing schedules of Selinexor in soft tissue sarcoma and related tumors has completed.
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CLINICAL_TRIALS trial_result · 2025-04-04Clinical Trial Update: Phase II Trial of Ribociclib and Everolimus in Advanced Dedifferentiated Liposarcoma (DDL) and Leiomyosarcoma (LMS) [Phase 2]
Phase II clinical trial evaluating ribociclib in combination with everolimus in advanced dedifferentiated liposarcoma and leiomyosarcoma; th…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: A Study of Nivolumab in Selected Uterine Cancer Patients [Phase 2]
Phase 2 study of Nivolumab in selected uterine cancers has completed enrollment and posted results in 2024.
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: Cytotoxic T Cells to Treat Relapsed EBV-positive Lymphoma [Phase 1]
Phase 1 trial testing EBV-specific cytotoxic T cells in relapsed EBV-positive lymphomas has completed, assessing safety and preliminary acti…
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CLINICAL_TRIALS trial_result · 2024-12-11Clinical Trial Update: A Study to Learn About the Study Medicine (Called Ontorpacept or TTI-621) Given Alone and in Combination With Doxorubicin in People With Leiomyosarcoma [Phase 2]
Pfizer's Phase 2 study of Ontorpacept (TTI-621) alone or with doxorubicin in leiomyosarcoma was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2024-11-25Clinical Trial Update: Lenvatinib and Eribulin in Advanced Soft Tissue Sarcoma [Phase 1, Phase 2]
Phase 1/2 study evaluating lenvatinib and eribulin in advanced soft tissue sarcoma has completed with posted results. The study includes lei…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Itacitinib in Treating Patients With Refractory Metastatic/Advanced Sarcomas [Phase 1]
Itacitinib was studied in a Phase 1 trial for patients with refractory metastatic/advanced sarcomas, but the study status is TERMINATED.
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CLINICAL_TRIALS trial_result · 2023-12-06Clinical Trial Update: ATX-101 in Advanced Dedifferentiated Liposarcoma and Leiomyosarcoma [Phase 2]
Phase 2 clinical trial update for ATX-101 in advanced dedifferentiated liposarcoma and leiomyosarcoma has been terminated with results poste…
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma [Phase 2]
Phase 2 trial evaluating doxorubicin with upfront dexrazoxane for advanced or metastatic soft tissue sarcoma has completed enrollment with r…
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CLINICAL_TRIALS trial_result · 2023-11-02Clinical Trial Update: A Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With Anticancer Agents [Phase 1, Phase 2]
Phase 1/2 trial evaluating OR2805, a anti-CD163 monoclonal antibody, alone and with anticancer agents for solid tumors, with unspecified sta…
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CLINICAL_TRIALS trial_result · 2023-10-10Clinical Trial Update: Treatment of Metastatic Soft Tissue Sarcoma (STS) Patients (FIBROSARC USA) [Phase 2]
Phase 2 trial update for treatment of metastatic soft tissue sarcoma (leiomyosarcoma) under FIBROSARC USA.
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CLINICAL_TRIALS trial_result · 2023-07-07Clinical Trial Update: M6620 (VX-970) in Selected Solid Tumors [Phase 2]
Phase 2 trial of M6620 (VX-970) in selected solid tumors completed; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2022-04-29Clinical Trial Update: Avelumab and Trabectedin in Treating Patients With Liposarcoma or Leiomyosarcoma That is Metastatic or Cannot Be Removed by Surgery [Phase 1, Phase 2]
Clinical trial evaluating avelumab plus trabectedin in metastatic or unresectable liposarcoma and leiomyosarcoma; the study has terminated w…
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CLINICAL_TRIALS trial_result · 2021-11-01Clinical Trial Update: Efficacy Study on Trabectedin in Retroperitoneal Leiomyosarcoma and Well Differentiated/Dedifferentiated Liposarcoma [Phase 2]
Phase 2 trial update on trabectedin for liposarcoma and leiomyosarcoma completed.
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CLINICAL_TRIALS trial_result · 2021-08-31Clinical Trial Update: A Study of LY3435151 in Participants With Solid Tumors [Phase 1]
Phase 1 study of LY3435151 in solid tumors, including triple-negative breast cancer, terminated with results posted.
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CLINICAL_TRIALS trial_result · 2021-02-04Clinical Trial Update: Avelumab in Combination With Gemcitabine in Advanced Leiomyosarcoma as a Second-line Treatment [Phase 2]
Phase 2 trial update evaluating avelumab in combination with gemcitabine for advanced, metastatic leiomyosarcoma as second-line therapy.
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CLINICAL_TRIALS trial_result · 2020-07-27Clinical Trial Update: Vorinostat (SAHA) in Uterine Sarcoma [Phase 2]
Phase 2 clinical trial testing vorinostat (SAHA) in uterine sarcoma was terminated; results posted in 2020.