Leg Ulcers
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: MAtrix Therapy for Hard-to-heal ChrOnic Wounds [NA]
A completed clinical trial evaluating Matrix Therapy for hard-to-heal chronic wounds, including chronic leg ulcers and diabetic foot ulcers.
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Insights Into Microbiome and Environmental Contributions to Sickle Cell Disease and Leg Ulcers Study (INSIGHTS Study)
A completed NHGRI-sponsored clinical study (INSIGHTS) investigates how the microbiome and environmental factors influence sickle cell diseas…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Functional and Mechanistic Characterization of Limb Ulcers in Patients With Sickle Cell Disease [NA]
A completed clinical trial presenting functional and mechanistic insights into limb ulcers in patients with sickle cell disease.
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CLINICAL_TRIALS trial_result · 2025-09-11Clinical Trial Update: Correlating Multispectral Near-Infrared Imaging to Standard Vascular Diagnostics
A clinical trial update notes ongoing recruitment for a study evaluating the relationship between multispectral near-infrared imaging and st…
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Resolution of Sickle Cell Leg Ulcers With Voxelotor [Phase 3]
A Phase 3 trial of voxelotor for resolution of sickle cell leg ulcers has been terminated, and results have been posted.
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CLINICAL_TRIALS trial_result · 2025-05-07Clinical Trial Update: Topical Sodium Nitrite in Sickle Cell Disease and Leg Ulcers [Phase 2]
A Phase 2 trial evaluating topical sodium nitrite for sickle cell disease and leg ulcers was terminated, with results posted.
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Efficacy and Safety of Light Compression System in the Local Treatment of Mixed Leg Ulcers (PROMETHEE Clinical Investigation) [NA]
A PROMETHEE clinical investigation sponsored by Laboratoires URGO is evaluating the efficacy and safety of a Light Compression System for lo…
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CLINICAL_TRIALS research · 2024-12-09Clinical Trial Update: Cell Therapy for Lower Limb Ulcers in Patients With Critical Limb Ischemia [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating a cell therapy for lower limb ulcers in patients with critical limb ischemia due to peripheral arterial …
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: A Prospective, Multi Centre, Interventional, Non-comparator, Open Label Study to Demonstrate the Efficacy, Safety, and Performance of ConvaFoam™ Dressings in the Management of Indicated Chronic Wound Types. [NA]
A completed multicenter, open-label interventional trial evaluating ConvaFoam Dressings for the management of chronic leg ulcers and pressur…
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Role of Tissue Oxygenation and the miR-210 Gene In Wound Healing
The clinical trial on tissue oxygenation and the miR-210 gene in wound healing for non-diabetic patients with chronic leg ulcers has been te…
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CLINICAL_TRIALS trial_result · 2023-05-10Clinical Trial Update: Evaluation Of An Advanced Borderless Dressing [NA]
A completed clinical trial evaluating an advanced borderless dressing for pressure ulcers, leg ulcers, and diabetic foot ulcers with results…
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CLINICAL_TRIALS trial_result · 2018-05-18Clinical Trial Update: Role of Platelet Rich Plasma in Enhancing Graft Take in Chronic Venous Ulcers [NA]
A completed clinical trial evaluating whether platelet-rich plasma improves graft take in chronic venous ulcers.
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CLINICAL_TRIALS trial_result · 2017-12-13Clinical Trial Update: Safety and Efficacy of Autologous Bone Marrow Stem Cells for Lower Extremity Ischemia Treating [Phase 1, Phase 2]
Clinical trial update on autologous bone marrow stem cells for lower extremity ischemia, reporting Phase 1 and Phase 2 data.
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CLINICAL_TRIALS trial_result · 2017-12-11Clinical Trial Update: Biatain Ag vs Biatain in the Treament of Leg Ulcers [NA]
A completed clinical trial comparing Biatain Ag to Biatain for the treatment of leg ulcers, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-02-28Clinical Trial Update: SANGUINATE™ in Sickle Cell Disease Associated Leg Ulcer [Phase 2]
Phase 2 study of SANGUINATE for leg ulcers in sickle cell disease has completed, reporting results from the trial.
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CLINICAL_TRIALS trial_result · 2017-01-13Clinical Trial Update: A Randomised Controlled Trial Comparing Vacuum Assisted Closure (V.A.C.®) With Modern Wound Dressings [NA]
A randomized controlled trial compared Vacuum Assisted Closure (V.A.C.®) with modern wound dressings for leg ulcers; the study has completed…
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CLINICAL_TRIALS trial_result · 2016-12-08Clinical Trial Update: Treatment of Chronic Leg Ulcers With Autologous Stromal Vascular Fraction [NA]
Clinical trial update on treating chronic leg ulcers with autologous stromal vascular fraction. The study status is unknown.
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CLINICAL_TRIALS research · 2016-08-19Clinical Trial Update: Remote Ischemic Conditioning for Treatment of Chronic Wounds [NA]
This clinical trial update covers remote ischemic conditioning for treating chronic wounds, with indications including leg ulcers and varico…
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CLINICAL_TRIALS research · 2016-07-25Clinical Trial Update: Clinical Feasibility of an Advanced Therapy Medicinal Product (ATMP) Preparation for Autologous Skin Regeneration in Case of Chronic Leg Ulcers [NA]
This clinical trial update discusses the feasibility of using an autologous advanced therapy medicinal product to regenerate skin in patient…
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CLINICAL_TRIALS trial_result · 2016-03-02Clinical Trial Update: Efficacy of 50% Nitrous Oxide/50% Oxygen Gas Premix in Chronic Leg Ulcer Debridement [NA]
A completed clinical trial evaluated the efficacy of a 50% nitrous oxide/50% oxygen gas premix used during debridement for chronic leg ulcer…
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CLINICAL_TRIALS research · 2015-10-22Clinical Trial Update: Assessment of Efficacy & Safety for a New Wound Dressing Urgo 310 3166 in the Local Treatment of VLU or Mixed Leg Ulcers [NA]
Clinical trial update evaluating the efficacy and safety of the Urgo 310/3166 wound dressing for venous leg ulcers and mixed leg ulcers.
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CLINICAL_TRIALS trial_result · 2015-08-13Clinical Trial Update: Evaluation of Integra® Artificial Dermis for the Treatment of Leg Ulcers
Clinical trial update on Integra® Artificial Dermis for leg ulcers. The study status is completed.
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CLINICAL_TRIALS trial_result · 2015-02-25Clinical Trial Update: Interest of a Systematic Biopsy for Hard-to-heal Leg Ulcers
A completed clinical trial evaluated the potential value of systematic biopsy for hard-to-heal leg ulcers.
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CLINICAL_TRIALS trial_result · 2015-01-09Clinical Trial Update: Compression Device Versus 4-layer Compression System [Phase 2]
A Phase 2 trial comparing a compression device with a 4-layer compression system in leg ulcers has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2014-05-05Clinical Trial Update: Topical Nitric Oxide Trial in Chronic Non-Healing Wounds [Phase 2]
A Phase 2 trial evaluating topical nitric oxide for chronic leg ulcers was terminated; results have been posted.