Latent Tuberculosis Infection
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Training Protocol on the Natural History of Tuberculosis
Sponsored by NIAID, this ClinicalTrials.gov entry outlines a training protocol to study the natural history of tuberculosis, including laten…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: 2R2: Higher Dose Rifampin for 2 Months vs Standard Dose Rifampin for Latent TB. [Phase 2]
Phase 2 trial comparing higher-dose rifampin given for 2 months with standard-dose rifampin for latent tuberculosis infection. The study ass…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Bedaquiline Roll-out Evidence in Contacts and People Living With HIV to Prevent TB [Phase 2, Phase 3]
A Phase 2/3 clinical trial update evaluating bedaquiline to prevent tuberculosis among contacts of TB patients and people living with HIV, f…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Parent Study Name: Pulmonary Rehabilitation to Reduce Post-Tuberculosis Morbidity (TB Pure) [NA]
This update describes an ongoing clinical trial (TB Pure) evaluating pulmonary rehabilitation to reduce post-tuberculosis morbidity, with re…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Isoniazid-Related Hepatotoxicity in Clinical Practice: Incidence and Predictors
A clinical trial update assessing the incidence and predictors of isoniazid-related hepatotoxicity in TB infection, including latent TB infe…
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: The Influence of Malnutrition, Diabetes Mellitus, and Helminth Infections on Biosignatures in Latent Tuberculosis in a South Indian Population
A completed clinical trial from NIAID in a South Indian population investigates how malnutrition, diabetes mellitus, and helminth infections…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Evaluation of a Novel Microbiological Diagnostic Test for Latent Mycobacterium Tuberculosis Infection
Ongoing clinical trial evaluating a novel microbiological diagnostic test for latent Mycobacterium tuberculosis infection; enrollment is by …
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Burden of Tuberculosis Among Pregnant and Postpartum Women in Guinea-Bissau [NA]
A ClinicalTrials.gov registry entry describing a study of the burden of tuberculosis among pregnant and postpartum women in Guinea-Bissau; t…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Shorter and Safer Treatment Regimens for Latent TB [Phase 2, Phase 3]
This clinical trial update indicates ongoing Phase 2/3 evaluations of shorter and safer treatment regimens for latent tuberculosis infection…
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FDA approval · 2026-01-27FDA Approved: PRIFTIN — Supplemental Application (sanofi-aventis U.S. LLC)
The FDA approved a supplemental application for PRIFTIN (rifapentine) from Sanofi-Aventis U.S. LLC.
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: One-month Latent Tuberculosis Treatment for Renal Transplant Candidates [Phase 4]
Phase 4 clinical trial update evaluating a one-month latent tuberculosis treatment regimen for patients with end-stage renal disease who are…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Window Prophylaxis for Pediatric Tuberculosis Prevention Trial [NA]
Trial update announcing ongoing recruitment for a pediatric window prophylaxis study to prevent tuberculosis in household contacts.
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: TB YOUTH - TB sYstemic Management Using One-month, Ultra-short TPT Regimen for scHool Contacts [Phase 3]
A Phase 3 trial evaluating a one-month ultra-short preventive therapy regimen for school contacts to manage latent tuberculosis infection.
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: Characterization of Tissue-Specific Immune Responses to Bronchoscopic Instillation of Mycobacterial Antigens Into the Human Lung [EARLY_Phase 1]
Early Phase 1 study characterizes tissue-specific immune responses to bronchoscopic instillation of mycobacterial antigens in the human lung…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Prevalence of Latent Tuberculosis Infection Among Hemodialysis Patients
This clinical trial update from Sohag University examines the prevalence of latent tuberculosis infection among patients with end-stage rena…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Short-course Regimens for the Treatment of Pulmonary Tuberculosis [Phase 2, Phase 3]
ClinicalTrials.gov update on Phase 2 and Phase 3 trials evaluating short-course regimens for pulmonary tuberculosis and latent tuberculosis …
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Brief Educational Video for Patients Prescribed LTBI Treatment [NA]
This clinical trial update describes a brief educational video for patients prescribed latent tuberculosis infection treatment, funded by Ka…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: Prospective Quality Improvement Project for High-Risk Diabetes Patients [NA]
This document reports the termination of a prospective quality improvement project for high-risk diabetes patients, which included monitorin…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: Effect of the Use of Low Intensity Therapeutic LASER [NA]
This completed clinical trial evaluates low intensity therapeutic laser for wound healing, including diabetic foot ulcers; latent tuberculos…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: TB Screening Improves Preventive Therapy Uptake [NA]
This trial update reports that screening for tuberculosis improves uptake of preventive therapy, suggesting that screening strategies could …
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Detection of Mycobacterium Tuberculosis in Blood of TB Patients and Their Contacts in Uganda
A clinical trial in Uganda examining detection of Mycobacterium tuberculosis in the blood of TB patients and their contacts, currently enrol…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Tuberculosis Clinical Trials Consortium Study 35 [Phase 1, Phase 2]
The Tuberculosis Clinical Trials Consortium Study 35, a Phase 1/Phase 2 trial sponsored by the CDC, has completed its investigation in laten…
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: Testing Health Workers At Risk to Advance Our Understanding of TB Infection
A Beth Israel Deaconess Medical Center-sponsored study is recruiting health workers to better understand tuberculosis infection risk and tra…
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CLINICAL_TRIALS research · 2025-05-09Clinical Trial Update: Economic Incentives and vDOT for Latent Tuberculosis Infection [NA]
A Johns Hopkins University clinical trial is evaluating economic incentives and video Directly Observed Therapy (vDOT) to improve treatment …
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CLINICAL_TRIALS research · 2025-05-06Clinical Trial Update: Systems Analysis and Improvement Approach to Prevent TB [NA]
This clinical trial update describes a systems analysis and improvement approach to prevent tuberculosis. The study is currently enrolling b…