Late-life Depression
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Effects of Specific Amino Acid Supplementation and Lifestyle Factors on Brain Ageing [NA]
A clinical trial update shows recruitment is ongoing to study whether specific amino acid supplementation and lifestyle factors influence br…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Dopaminergic Dysfunction in Late-Life Depression [Phase 2]
A Phase 2 clinical trial from Vanderbilt University Medical Center is investigating dopaminergic dysfunction in late-life depression and its…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Accelerated vs. Conventional Theta Burst Stimulation for Late-life Depression [NA]
A clinical trial is evaluating accelerated versus conventional theta burst stimulation for late-life depression and is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Characterizing Cognitive Decline in Late Life Depression: The ADNI Depression Project
This update describes the ADNI Depression Project led by the University of Southern California to study cognitive decline in individuals wit…
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: Nitrous Oxide for Late-Life Depression - PROTO-BRAIN [NA]
The PROTO-BRAIN study evaluating nitrous oxide for late-life depression and treatment-resistant depression has completed.
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Effects of Mindfulness or Brain Stimulation Intervention for Late-life Adults in Taiwan Urban and Rural Areas [NA]
This ClinicalTrials.gov entry describes an ongoing study in Taiwan evaluating mindfulness and brain stimulation interventions for late-life …
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CLINICAL_TRIALS research · 2025-05-12Clinical Trial Update: Developing a Peer Support Intervention for Depression in SCD [NA]
Massachusetts General Hospital is recruiting for a clinical trial to develop a peer support intervention for depression in older adults, inc…
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CLINICAL_TRIALS research · 2024-10-29Clinical Trial Update: Chronic Anergic Depression IDentification - Magnetic Resonance Imaging Exploration in the Elderly of Traits Related to Onset [NA]
A new clinical trial sponsored by University Hospital, Strasbourg, is investigating MRI-based traits related to onset in elderly patients wi…
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CLINICAL_TRIALS other · 2024-08-22Clinical Trial Update: TBS,TMS, Suicidal Ideation, Magnetic Resonance Imaging, Dorsolateral Prefrontal Cortex, Ventrolateral Prefrontal Cortex [NA]
Clinical trial update evaluating transcranial magnetic stimulation (TMS) and theta burst stimulation (TBS) for late-life depression. The upd…
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CLINICAL_TRIALS research · 2024-06-24Clinical Trial Update: One-Year Trajectory of Cognitive Changes in Patients With Late-life Depression in the Short Term
This clinical trial update describes a Fujian Medical University study investigating the one-year cognitive trajectory of patients with late…
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CLINICAL_TRIALS trial_result · 2023-02-08Clinical Trial Update: Ketamine for Older Adults Pilot [Phase 4]
Pilot Phase 4 trial investigating ketamine for treatment resistant depression in older adults has completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-05-24Clinical Trial Update: Optimizing Outcomes of Treatment-Resistant Depression in Older Adults [Phase 4]
Phase 4 trial update evaluating outcomes for treatment-resistant depression in older adults; results were posted in May 2022.
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CLINICAL_TRIALS trial_result · 2022-01-26Clinical Trial Update: Pathophysiology of Neurodegeneration in Late-life Depression (AV45+THK) [Phase 2]
Phase 2 trial investigating pathophysiology of neurodegeneration in late-life depression using AV45+THK.
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CLINICAL_TRIALS trial_result · 2021-08-09Clinical Trial Update: Ketamine for Treatment Resistant Late-Life Depression [Phase 3]
A Phase 3 trial evaluating ketamine for treatment resistant late-life depression has completed with results posted.
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CLINICAL_TRIALS withdrawal · 2018-06-25Clinical Trial Update: A Breathing-Based Meditation Intervention for Patients With Treatment Resistant Late Life Depression [Phase 1]
A Phase 1 trial evaluating a breathing-based meditation intervention for treatment-resistant late-life depression was withdrawn; no results …
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CLINICAL_TRIALS trial_result · 2015-04-07Clinical Trial Update: Determining Changes in Brain Structure Associated With Symptoms of Late-life Depression
The clinical trial investigating changes in brain structure associated with late-life depression has completed.
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CLINICAL_TRIALS trial_result · 2014-02-26Clinical Trial Update: Automatic Self Transcending Meditation (ASTM) Versus Heart Rate Variability (HRV) Biofeedback in Patients With Late Life Depression (LLD): a Longitudinal Pilot Feasibility Study [NA]
A longitudinal pilot feasibility clinical trial compared Automatic Self-Transcending Meditation (ASTM) to heart rate variability (HRV) biofe…
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CLINICAL_TRIALS trial_result · 2010-11-05Clinical Trial Update: Fish Oil Supplementation in Late-life Depression [NA]
This record notes the completion of a clinical trial evaluating fish oil supplementation for late-life depression, conducted by Taipei City …