Laryngeal Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN) [Phase 2]
A Phase 2 trial assesses neoadjuvant chemotherapy combined with a PD-1 inhibitor for head and neck squamous cell carcinoma with the goal of …
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation [NA]
A clinical trial update describes remote audiometry being studied to monitor treatment-related hearing loss in patients with head and neck s…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial evaluating pembrolizumab given alone versus the standard chemotherapy with radiation after surgery for recurrent head…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer [Phase 2, Phase 3]
A Phase 2/3 clinical trial update evaluating either docetaxel plus cetuximab or adding atezolizumab to standard chemotherapy and radiation f…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer [Phase 1]
A Phase 1 clinical trial is evaluating the addition of the AKT inhibitor ipatasertib to standard chemotherapy and radiation for locally adva…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer [Phase 2]
Phase 2 trial evaluating cemiplimab plus CDX-1140 given before surgery to determine if the combination improves outcomes versus cemiplimab a…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Window of Opportunity in Preserving Laryngeal Function Trial [Phase 2]
A Phase 2 clinical trial update indicates recruitment is ongoing for a window-of-opportunity study aimed at preserving laryngeal function in…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Addition of an Anti-cancer Drug, Ipatasertib, to the Usual Immunotherapy Treatment (Pembrolizumab) in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck [Phase 2]
A Phase 2 clinical trial is exploring adding ipatasertib to pembrolizumab in patients with recurrent or metastatic head and neck squamous ce…
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CLINICAL_TRIALS other · 2026-04-03Clinical Trial Update: Comparing Cisplatin Every Three Weeks to Cisplatin Weekly When Combined With Radiation for Patients With Advanced Head and Neck Cancer [Phase 2, Phase 3]
NRG Oncology reports suspension of a phase 2/3 trial comparing cisplatin dosing every three weeks versus weekly when given with radiation fo…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: First Line Weekly Chemo/Immunotherapy for Metastatic Head/Neck Squamous Cell Carcinoma Patients [Phase 2]
Phase 2 trial evaluating first-line weekly chemotherapy combined with immunotherapy for metastatic head and neck squamous cell carcinoma; th…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery [Phase 2]
A Phase 2 clinical trial is assessing the addition of cisplatin to postoperative radiation therapy for stage III-IV squamous cell carcinoma …
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Immune Biomarker Study for Cisplatin-ineligible Patients Receiving Chemoradiotherapy With Docetaxel
Clinical trial update notes ongoing recruitment for an immune biomarker study in cisplatin-ineligible patients receiving chemoradiotherapy w…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Combining Radiation Therapy With Immunotherapy for the Treatment of Metastatic Squamous Cell Carcinoma of the Head and Neck [Phase 3]
Phase 3 trial evaluating combining radiation therapy with immunotherapy for metastatic and stage IV squamous cell carcinomas of the head and…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Cisplatin, Docetaxel, and Pembrolizumab in Treating Patients With Stage II-III Laryngeal Cancer [Phase 2]
Phase 2 trial evaluating cisplatin, docetaxel, and pembrolizumab for stage II–III laryngeal squamous cell carcinoma; the study is active but…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Cemiplimab, Low-Dose Paclitaxel and Carboplatin for the Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck [Phase 2]
This document provides an update on a Phase 2 clinical trial evaluating cemiplimab in combination with low-dose paclitaxel and carboplatin f…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors [Phase 2]
A Phase 2 study evaluating vobramitamab duocarmazine in metastatic castration-resistant prostate cancer and other solid tumors was terminate…
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CLINICAL_TRIALS other · 2026-02-06Clinical Trial Update: Intralesional Chemotherapy (IC): Cisplatin + Epinephrine [Phase 2]
A Phase 2 clinical trial update for intralesional chemotherapy using cisplatin plus epinephrine in laryngeal squamous cell carcinoma, curren…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Combining Immunotherapy Salvage Surgery & IORT Tx Persistent/Recurrent Head & Neck Cancer [Phase 1]
Phase 1 trial evaluating combining immunotherapy salvage surgery with intraoperative radiotherapy (IORT) for head and neck cancer, including…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 trial evaluating pembrolizumab in combination with cetuximab for recurrent/metastatic head and neck squamous cell carcinoma; the stu…
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: Activity and Safety of Peptide-based Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck. [Phase 2]
A Phase 2 clinical trial evaluating a peptide-based immunotherapy for head and neck squamous cell carcinoma was terminated; the update repor…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: IRX-2 Regimen and Durvalumab, for Incurable H&N Squamous Cell Carcinoma [Phase 1]
Phase 1 study evaluating IRX-2 regimen with durvalumab for incurable head and neck squamous cell carcinoma has completed, including multiple…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Personalized Elective Neck Irradiation Guided by Sentinel Lymph Node Biopsy in Larynx and Pharynx Cancer. The PRIMO Study. [Phase 3]
Phase 3 PRIMO study investigating personalized elective neck irradiation guided by sentinel lymph node biopsy for laryngeal and pharyngeal c…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: Comparing an Investigational Scan (F-18 NaF PET/CT) to Standard of Care Imaging (F-18 FDG PET/CT) for Evaluating Vascular Complications in Patients Receiving Radiation Therapy for Head and Neck Cancer [EARLY_Phase 1]
This early-phase 1 clinical trial compares an investigational F-18 NaF PET/CT imaging approach to standard F-18 FDG PET/CT for evaluating va…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Compartmentalized Postoperative Radiotherapy in Head and Neck Cancer [Phase 2]
A Phase 2 clinical trial evaluating compartmentalized postoperative radiotherapy in head and neck cancer, currently not yet recruiting.
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CLINICAL_TRIALS other · 2025-09-18Clinical Trial Update: Proactive Risk-based Optimization & Notifications for Treatment & Outcomes in Head & Neck Cancer [NA]
Clinical trial update announcing a study on proactive risk-based optimization and notifications for treatment and outcomes in head and neck …