Large Granular Lymphocytic Leukemia

• CLINICAL_TRIALS research · 2026-04-17
  Clinical Trial Update: A Study of DR-01 in Subjects With Large Granular Lymphocytic Leukemia or Cytotoxic Lymphomas [Phase 1, Phase 2]

  A study of DR-01 by Dren Bio is ongoing in Phase 1/Phase 2 to treat several T-cell and NK-cell lymphomas, with recruitment currently underwa…

• CLINICAL_TRIALS trial_result · 2026-02-05
  Clinical Trial Update: Siltuximab in Large Granular Lymphocytic Leukemia (LGLL) [EARLY_Phase 1]

  An early-phase 1 trial of siltuximab for Large Granular Lymphocytic Leukemia has been terminated. The sponsor is H. Lee Moffitt Cancer Cente…

• CLINICAL_TRIALS research · 2025-11-18
  Clinical Trial Update: JAK1 Inhibitor Golidocitnib for the Treatment of Relapsed/Refractory Indolent T/NK-cell Lymphomas [Phase 2]

  Clinical trial update indicates a Phase 2 study of the JAK1 inhibitor golidocitnib for relapsed/refractory indolent T- and NK-cell lymphomas…

• CLINICAL_TRIALS trial_result · 2025-03-19
  Clinical Trial Update: Safety, PK, PD, Clinical Activity of KT-333 in Adult Patients With Refractory Lymphoma, Large Granular Lymphocytic Leukemia, Solid Tumors [Phase 1]

  Phase 1 trial of KT-333 in adults with refractory lymphomas and solid tumors reports safety, pharmacokinetics, pharmacodynamics, and prelimi…

• CLINICAL_TRIALS trial_result · 2025-01-13
  Clinical Trial Update: Prospective, Multicentric, Phase II Randomized Controlled Trial on Two Parallel Groups Comparing the Efficacy of Two Immunosuppressive Drugs (methotrexate, Cyclophosphamide) in Large Granular Lymphocytes Leukemia [Phase 2]

  Phase II randomized trial comparing methotrexate versus cyclophosphamide in large granular lymphocytic leukemia has been completed to assess…

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• CLINICAL_TRIALS trial_result · 2024-05-29
  Clinical Trial Update: Efficacy and Safety of PI3K Inhibitors in Relapsed/Refractory Large Granular T Lymphocytic Leukemia [Phase 1]

  Phase 1 study evaluating the efficacy and safety of PI3K inhibitors in relapsed/refractory large granular lymphocytic leukemia has completed…

• CLINICAL_TRIALS trial_result · 2012-07-06
  Clinical Trial Update: Effect of Cyclosporine Therapy on Gene Expression in Patients With Large Granular Lymphocyte Leukemia [Phase 2]

  A Phase 2 study assessing the effect of cyclosporine therapy on gene expression in patients with Large Granular Lymphocytic Leukemia; the tr…