Klinefelter Syndrome
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Fertility Preservation in Cases of Klinefelter Syndrome. [NA]
The document notes the completion of a clinical trial on fertility preservation options for individuals with Klinefelter syndrome.
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Long-term Systematic Follow-up of Patients With Klinefelter Syndrome Followed at the Department of Growth and Reproduction, Rigshospitalet
The document describes an ongoing long-term systematic follow-up study of patients with Klinefelter Syndrome at Rigshospitalet in Denmark; e…
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Thyroid Function and Structure in Klinefelter Syndrome
The trial evaluates thyroid function and thyroid structure in individuals with Klinefelter syndrome and is currently recruiting, sponsored b…
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CLINICAL_TRIALS trial_result · 2025-02-19Clinical Trial Update: Klinefelter Syndrome and Testosterone Treatment in Puberty [Phase 4]
It provides a Phase 4 clinical trial update regarding testosterone treatment during puberty for individuals with Klinefelter Syndrome. Recru…
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CLINICAL_TRIALS trial_result · 2024-11-13Clinical Trial Update: Retrospective Analysis of the Neonatal Management of Patients with an Antenatal Diagnosis of Genital Development Variation At the Hospital of Lyon
A completed retrospective analysis examining how neonates with an antenatal diagnosis of genital development variation were managed at the H…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: Interrogating Fatty Acid Metabolism Impairment and Clinical Correlates in Males with Klinefelter Syndrome [Phase 4]
A Phase 4 clinical trial investigating fatty acid metabolism impairment and clinical correlates in males with Klinefelter syndrome is curren…
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CLINICAL_TRIALS research · 2024-05-09Clinical Trial Update: The eXtroardinarY Babies Study: Natural History of Health and Neurodevelopment in Infants and Young Children With Sex Chromosome Trisomy
This update indicates the eXtroardinarY Babies Study is currently recruiting to observe natural history of health and neurodevelopment in in…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: Relationship Between Anogenital Distance, Serum AMH, and mTESE in Klinefelter Syndrome
A completed clinical study evaluating how anogenital distance and serum AMH relate to micro-TESE outcomes in men with Klinefelter syndrome.
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CLINICAL_TRIALS trial_result · 2024-01-05Clinical Trial Update: Sex Steroids Balance for Metabolic and Reproductive Health in Klinefelter Syndrome [Phase 3]
Phase 3 clinical trial update examining sex steroid balance for metabolic and reproductive health in Klinefelter syndrome.
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CLINICAL_TRIALS trial_result · 2022-05-06Clinical Trial Update: TESTO: Testosterone Effects on Short-Term Outcomes in Infants With XXY [Phase 4]
A Phase 4 clinical trial evaluating testosterone effects on short-term outcomes in infants with Klinefelter syndrome has completed.
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CLINICAL_TRIALS trial_result · 2021-08-10Clinical Trial Update: Study of Psychological and Motor Effects of Testosterone in Adolescents With XXY/Klinefelter Syndrome [NA]
Completed clinical trial studying psychological and motor effects of testosterone in adolescents with Klinefelter syndrome (XXY).
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CLINICAL_TRIALS trial_result · 2021-07-30Clinical Trial Update: RA-2 13-cis Retinoic Acid (Isotretinoin) [Phase 2]
Phase 2 clinical trial update for RA-2 13-cis retinoic acid (isotretinoin) involving male infertility conditions; study has completed with r…
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CLINICAL_TRIALS trial_result · 2021-07-08Clinical Trial Update: Androgen Effect on Klinefelter Syndrome Motor Outcome [Phase 2]
Phase 2 trial investigating the effect of androgens on motor outcomes in individuals with Klinefelter syndrome; study completed with posted …
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CLINICAL_TRIALS trial_result · 2020-04-15Clinical Trial Update: Body Composition in Infants With Klinefelter Syndrome and Effects of Testosterone Treatment [Phase 4]
Phase 4 trial update on body composition in infants with Klinefelter syndrome and the effects of testosterone treatment; results posted in 2…
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CLINICAL_TRIALS trial_result · 2018-09-25Clinical Trial Update: Androgen for Leydig Cell Proliferation [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating an androgen therapy for Leydig cell proliferation disorders in men with Klinefelter syndrome and hyper…
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CLINICAL_TRIALS trial_result · 2018-07-24Clinical Trial Update: Fertility Assessment in Patients With Klinefelter Syndrome
This clinical trial update states that the fertility assessment study in patients with Klinefelter syndrome was terminated.
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CLINICAL_TRIALS trial_result · 2016-10-04Clinical Trial Update: Subcapsular Orchiectomy in Men With Klinefelter Syndrome [NA]
This clinical trial update reports the completion of a study evaluating subcapsular orchiectomy in men with Klinefelter syndrome.
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CLINICAL_TRIALS trial_result · 2016-06-07Clinical Trial Update: Human Chorionic Gonadotropin Stimulation Effects on Steroidogenesis in Men With Klinefelter Syndrome [NA]
This Clinical Trial Update notes the completion of a study evaluating the effects of human chorionic gonadotropin stimulation on steroidogen…
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CLINICAL_TRIALS trial_result · 2016-05-24Clinical Trial Update: X-chromosome Inactivation, Epigenetics and the Transcriptome
This completed University of Aarhus trial investigates X-chromosome inactivation, epigenetics, and transcriptome characteristics in Turner s…
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CLINICAL_TRIALS withdrawal · 2015-12-03Clinical Trial Update: Adaptive Behavior Assessment of Men With 49, XXXXY, Klinefelter Syndrome
A clinical trial investigating adaptive behavior in men with 49, XXXXY Klinefelter syndrome has been withdrawn.
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CLINICAL_TRIALS research · 2015-06-02Clinical Trial Update: Neuropsychologic, Neuroradiologic, Endocrinologic, and Genetic Aspects of Klinefelter Syndrome
This clinical trial update summarizes neuropsychologic, neuroradiologic, endocrinologic, and genetic aspects of Klinefelter syndrome studied…
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CLINICAL_TRIALS trial_result · 2015-06-02Clinical Trial Update: Life Quality and Health in Patients With Klinefelter Syndrome
This entry reports a completed clinical trial conducted at the University of Aarhus evaluating life quality and health in individuals with K…
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CLINICAL_TRIALS trial_result · 2015-04-10Clinical Trial Update: Sperm Production in Kleinfelter Syndrome Patients After Mesenchymal Stem Cell Injection [NA]
A completed clinical trial evaluated sperm production in men with Klinefelter syndrome after mesenchymal stem cell injections.
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CLINICAL_TRIALS trial_result · 2014-05-15Clinical Trial Update: Klinefelter Fertility Preservation [NA]
This update indicates the clinical trial NCT01817296 on fertility preservation in Klinefelter syndrome has completed. The sponsor listed is …
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CLINICAL_TRIALS trial_result · 2013-07-02Clinical Trial Update: Non-invasive Prenatal Diagnostic Validation Study
The study completed validation of a non-invasive prenatal diagnostic test for fetal chromosomal abnormalities.