Kidney Transplantation
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Sign up freeTop drugs studied for this disease
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EMA approval · 2026-06-04EMA Authorised: Rapamune (sirolimus) — Pfizer Europe MA EEIG
European Medicines Agency authorises Rapamune (sirolimus) for graft rejection and kidney transplantation.
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CLINICAL_TRIALS trial_result · 2026-06-04Clinical Trial Update: Renal Function Evaluation After Reduction of Cyclosporine A Dose in Renal Transplant Patients [Phase 3]
Phase 3 clinical trial evaluating renal function after reducing cyclosporine A dose in renal transplant patients; completed study.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Model-Informed Precision Dosing of Tacrolimus in Pediatric Kidney Transplantation
This clinical trial update outlines a study evaluating model-informed precision dosing of tacrolimus in pediatric kidney transplant recipien…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: COVID Protection After Transplant-Immunosuppression Reduction [Phase 2]
Phase 2 trial evaluating whether reducing transplant-immunosuppression around COVID-19 exposure provides protection for kidney and liver tra…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Use of Predigraft in Kidney Transplant Patients [NA]
This entry reports the completion of a clinical trial evaluating Predigraft in kidney transplant patients.
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Feasibility Study for the Comprehensive Overweight/Obesity Management Pre-Kidney Transplant (COMPKT) Program [NA]
This clinical trial update describes a feasibility study for the Comprehensive Overweight/Obesity Management Pre-Kidney Transplant (COMPKT) …
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Empagliflozin Treatment in Kidney Transplant Recipients [Phase 4]
Phase 4 clinical trial evaluating empagliflozin in kidney transplant recipients is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Observational Single-center Study of the Relationship Between Arterial Hypertension and Hypervolemia Defined by Self-measurement of Impedancemetry in Kidney Transplant Patients With Transplantation Less Than 6 Months Old
An observational single-center study is evaluating the relationship between arterial hypertension and hypervolemia, as measured by self-meas…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Study to Compare the Safety and Efficacy of Sirolimus (Rapamune) to Tacrolimus (Advagraf) Associated to Mycophenolate Mofetil (CellCept) Between 12 and 36 Months After Kidney Transplantation [Phase 3]
Phase 3 clinical trial comparing sirolimus plus mycophenolate mofetil to tacrolimus plus mycophenolate mofetil in kidney transplant recipien…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: The EFfect of FinErenone in Kidney TransplantiOn Recipients: The EFFEKTOR Study [Phase 2]
A Phase 2 clinical trial (EFFEKTOR) is evaluating finerenone in kidney transplant recipients, with recruitment currently ongoing.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Shared Decision Making for Kidney Transplant Candidates to Plan for an Organ Offer Decision [NA]
A completed clinical trial investigating how kidney transplant candidates use shared decision making to plan for organ offer decisions.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: MRI Technical Development and Applications in Kidney Disease
An update on an MRI technology development study for kidney disease and kidney transplantation, outlining the research aims and noting that …
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Subcutaneous Abatacept in Renal Transplant Recipients [Phase 1]
Phase 1 study evaluating subcutaneous abatacept in kidney transplant recipients has completed, with results posted.
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Kidney Transplant Preemptive Therapy or Prophylaxis for CMV Prevention in D+R Recipients [Phase 3]
Phase 3 clinical trial evaluating preemptive therapy or prophylaxis to prevent CMV infection in donor CMV-positive/recipient CMV-negative ki…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Kidney Protective Jacket [NA]
An ongoing clinical trial update notes recruitment for the Kidney Protective Jacket from iiShield in kidney transplant patients.
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: Dose-adjustment of Enoxaparin by a Bayesian Pharmacological Approach in Pediatric Kidney Transplant Recipients (OPTI-TREX) [Phase 4]
Phase 4 trial evaluating dose-adjustment of enoxaparin in pediatric kidney transplant recipients using a Bayesian pharmacological approach; …
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: Study of Efficacy, Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) of an Anti-CD40 Monoclonal Antibody, CFZ533, in Kidney Transplant Recipients [Phase 2]
Phase 2 study evaluating CFZ533 (iscalimab), an anti-CD40 monoclonal antibody, in kidney transplant recipients to assess efficacy, safety, t…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Assessment of Biomarker-Guided CNI Substitution In Kidney Transplantation [Phase 2]
Phase 2 clinical trial assessing biomarker-guided substitution of calcineurin inhibitors in kidney transplantation; currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: The Role of ImmuKnow® in the Management of Immunosuppressants in the Renal Transplant Patient [Phase 4]
A Phase 4 clinical trial evaluating the use of ImmuKnow to guide immunosuppressant management in kidney transplant recipients was terminated…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Impact of ExtraCorporeal Phototherapy (ECP) on Auxiliary Follicular T-lymphocytes and Circulating B-lymphocytes During Chronic AntiBody-Mediated Rejection in Kidney Transplantation. [NA]
This clinical trial investigates how extracorporeal photopheresis (ECP) affects auxiliary follicular T-lymphocytes and circulating B-lymphoc…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: ABO- or HLA- Incompatible LDKT Compared to Waitlist/DDKT in Elderly Patients
This completed clinical trial from Seoul National University Hospital compares ABO- or HLA-incompatible living-donor kidney transplantation …
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: (TNX-1500) in Kidney Transplant Recipients [Phase 2]
A Phase 2 clinical trial update for TNX-1500 in kidney transplant recipients, with the study status listed as NOT_YET_RECRUITING.
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: REgulatory T Cell Therapy to Achieve Immunosuppression REduction [Phase 2]
Phase 2 clinical trial in kidney transplantation evaluating regulatory T cell therapy to reduce immunosuppression. The study is currently re…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Study to Compare the Efficacy and Safety After Conversion to RaparoBell® or My-Rept® in Kidney Transplant Patients [Phase 4]
Phase 4 trial evaluating the efficacy and safety after conversion to RaparoBell or My-Rept in kidney transplant patients. The study is curre…
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CLINICAL_TRIALS trial_result · 2026-02-13Clinical Trial Update: Tolerance by Engaging Antigen During Cellular Homeostasis [Phase 1]
Phase 1 clinical trial update from NIAID evaluating a tolerance-inducing approach called 'Tolerance by Engaging Antigen During Cellular Home…