Keratoconus
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Intacs Prescription Inserts for Keratoconus Patients [NA]
This clinical trial update notes an ongoing study evaluating Intacs prescription inserts for keratoconus patients, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: A Randomized Clinical Trial of Ex Vivo Corneal Cross-Linking of Donor Keratoplasty Tissue for Keratoconus Used for Keratoplasty in Keratoconus Patients [NA]
A randomized clinical trial evaluating ex vivo corneal cross-linking of donor keratoplasty tissue for keratoconus in keratoplasty patients; …
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Artificial Intelligence-assisted Diagnosis in Ophthalmology
Clinical trial update on AI-assisted diagnosis in ophthalmology; the study is currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Dextenza Versus Topical Steroid Eye Drops for Postoperative Management Following Corneal Crosslinking [Phase 1, Phase 2]
A Phase 1/2 clinical trial comparing Dextenza to topical steroid eye drops for post-operative management after corneal crosslinking in kerat…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Electrophysiological Changes in Cases of Different Stages of Keratoconus
A clinical trial update describing a study of electrophysiological changes in keratoconus across disease stages; the study is currently acti…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Corneal Biomechanical Analysis Using Brillouin Microscopy
An ongoing study evaluating corneal biomechanical properties in keratoconus using Brillouin microscopy. Enrollment is by invitation.
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Placebo-controlled Study to Evaluate the Safety and Efficacy of GLK-221 Ophthalmic Solution in Subjects With Keratoconus [Phase 2]
A Phase 2 placebo-controlled study to evaluate the safety and efficacy of GLK-221 ophthalmic solution in subjects with keratoconus is curren…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Study of TN-001 Topical Eyedrops for Keratoconus [Phase 1, Phase 2]
A clinical trial update indicates TN-001 topical eyedrops for keratoconus are in Phase 1/2 and currently enrolling by invitation.
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Compassionate Use Study of Epi-ON Corneal Collagen Crosslinking Performed Using UVA Exposure on Eyes With Ectatic Corneal Diseases for Subjects With Down Syndrome [Phase 3]
Phase 3 compassionate-use trial evaluating epithelial-on corneal collagen crosslinking with UVA exposure for eyes with ectatic corneal disea…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: PRoTECT: Corneal Wavefront Guided PRK + Epi-off CXL vs. PTK+Epi-off CXL in Keratoconus [NA]
Clinical trial update for the PRoTECT study comparing corneal wavefront guided PRK + epi-off cross-linking versus PTK + epi-off cross-linkin…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: First in Human Study to Assess Safety and Efficacy of an Implantable Nitinol Device in the Treatment of Keratoconus [NA]
A first-in-human study is evaluating the safety and efficacy of an implantable nitinol device for treating keratoconus. The trial is current…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Investigator Initiated, Prospective Study of Xenia Corneal Lenticule [NA]
Investigator-initiated prospective study of Xenia Corneal Lenticule for keratoconus is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
A clinical trial update announcing recruitment for a study using functional MRI and in vivo confocal microscopy to evaluate corneal cross-li…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal Ectasia
A clinical trial is evaluating Brillouin microscopy as a diagnostic approach for corneal ectasia, including keratoconus and Fuchs' endotheli…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: Corneal Elastography and Patient Specific Modeling
A Cleveland Clinic-sponsored clinical trial is evaluating corneal elastography and patient-specific modeling for keratoconus and related cor…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking in Eyes With Corneal Ectasia [Phase 2]
A Phase 2 clinical trial evaluating the safety and effectiveness of the PXL-Platinum 330 System for corneal cross-linking in eyes with corne…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: AI-Orchestrated Workflow Versus Consultant Ophthalmologist for Refractive Surgery and Keratoconus Diagnosis (AEYE Trial)
A clinical trial comparing an AI-driven workflow to a consultant ophthalmologist for diagnosing keratoconus and guiding refractive surgery; …
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Scleral Lens Fitting Using Wide-Field OCT
Clinical trial update describing a study on scleral lens fitting using wide-field OCT for keratoconus with irregular corneal contour; recrui…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: OCT in Diagnosis of Irregular Corneas
A clinical trial update describing an OCT-based diagnostic approach for irregular corneas, including keratoconus and other corneal condition…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Risk Factors and Progression of Keratoconus [NA]
This clinical trial update describes a study on risk factors and progression of keratoconus. It is currently recruiting at University Hospit…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: The K-Map Study, Global Prevalence of KC
The K-Map Study is currently recruiting at University Hospital, Geneva to investigate the global prevalence of keratoconus.
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: Use of a Freeze-dried Amniotic Membrane Post Crosslinking in Subjects With Progressive Keratoconus [Phase 3]
Phase 3 clinical trial evaluating the use of a freeze-dried amniotic membrane after corneal crosslinking for progressive keratoconus; curren…
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CLINICAL_TRIALS research · 2025-04-07Clinical Trial Update: Evaluation of Corneal Epithelial Mapping in Diagnosis of Early Keratoconus by Anterior Segment Optical Coherence Tomography
This clinical trial evaluates corneal epithelial mapping using anterior segment optical coherence tomography to aid early diagnosis of kerat…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: McNeel Eye Center Corneal Crosslinking Study [NA]
A clinical trial update for a corneal crosslinking study in keratoconus conducted by McNeel Eye Center; the trial is currently active but no…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Detection of Keratoconus Progression Using Machine Learning
Clinical trial update on detecting progression of keratoconus using machine learning techniques. The study is currently active but not recru…