Juvenile Myelomonocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies [Phase 2]
Phase 2 clinical trial update evaluating TCRαβ-depleted progenitor cell graft with added memory T-cell donor lymphocyte infusion and selecti…
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CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases [Phase 2]
A Phase 2 clinical trial is testing alpha/beta T cell and CD19+ B cell depletion in allogeneic stem cell transplantation for malignant disea…
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: Trametinib in Treating Patients With Relapsed or Refractory Juvenile Myelomonocytic Leukemia [Phase 2]
A Phase 2 clinical trial update on trametinib for relapsed or refractory Juvenile Myelomonocytic Leukemia (JMML), including patients with Ne…
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: Stem Cell Transplant for Juvenile Myelomonocytic Leukemia (JMML) [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating stem cell transplantation for Juvenile Myelomonocytic Leukemia (JMML) conducted by Masonic C…
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Calcineurin Inhibitor at Patients With Hemoblastosis [Phase 3]
Phase 3 clinical trial evaluating a post-transplant immunomodulatory regimen (cyclophosphamide, abatacept, vedolizumab, and a calcineurin in…
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CLINICAL_TRIALS trial_result · 2021-02-02Clinical Trial Update: Sorafenib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating sorafenib in pediatric patients with relapsed or refractory solid tumors or leukemia; results completed …
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CLINICAL_TRIALS trial_result · 2020-10-12Clinical Trial Update: Donor Lymphocyte Infusion With Azacitidine to Prevent Hematologic Malignancy Relapse After Stem Cell Transplantation [Phase 2]
Phase 2 clinical trial evaluating donor lymphocyte infusion with azacitidine to prevent relapse after stem cell transplantation.
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CLINICAL_TRIALS trial_result · 2020-05-04Clinical Trial Update: Treosulfan-based Conditioning in Paediatric Patients With Haematological Malignancies [Phase 2]
Phase 2 trial update evaluating treosulfan-based conditioning in pediatric patients with hematological malignancies.
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CLINICAL_TRIALS trial_result · 2019-07-11Clinical Trial Update: Study With Azacitidine in Pediatric Subjects With Newly Diagnosed Advanced Myelodysplastic Syndrome (MDS) and Juvenile Myelomonocytic Leukemia (JMML) [Phase 2]
A Phase 2 clinical trial evaluating azacitidine in pediatric patients with newly diagnosed advanced myelodysplastic syndrome and juvenile my…
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CLINICAL_TRIALS trial_result · 2018-12-05Clinical Trial Update: Busulfan, Cyclophosphamide, and Melphalan or Busulfan and Fludarabine Phosphate Before Donor Hematopoietic Cell Transplant in Treating Younger Patients With Juvenile Myelomonocytic Leukemia [Phase 2]
Phase 2 trial evaluating conditioning regimens with busulfan-based chemotherapy before donor hematopoietic cell transplant in younger patien…
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CLINICAL_TRIALS trial_result · 2018-07-19Clinical Trial Update: Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer
This Clinical Trial Update describes a study collecting and storing malignant and related samples from young cancer patients; the trial stat…
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Donor Bone Marrow Transplant With or Without G-CSF in Treating Young Patients With Hematologic Cancer or Other Diseases [Phase 3]
Phase 3 trial evaluating donor bone marrow transplant with or without G-CSF in young patients with hematologic cancers or related diseases; …
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CLINICAL_TRIALS trial_result · 2017-02-20Clinical Trial Update: T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic Transplant [Phase 2]
Phase 2 trial of T-cell replete haploidentical donor hematopoietic stem cell transplantation with natural killer (NK) cell support in hemato…
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CLINICAL_TRIALS trial_result · 2016-05-03Clinical Trial Update: Mismatched Family Member Donor Transplantation for Children and Young Adults With High Risk Hematological Malignancies [Phase 2]
Phase 2 clinical trial update on mismatched family member donor stem cell transplantation in children and young adults with high-risk hemato…
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CLINICAL_TRIALS trial_result · 2016-05-02Clinical Trial Update: Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior Transplantation [Phase 2]
Phase 2 clinical trial evaluating repeat transplantation for relapsed or refractory hematologic malignancies after prior transplant; the stu…
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CLINICAL_TRIALS trial_result · 2015-04-22Clinical Trial Update: Allogenic Stem Cell Transplantation in Patients With High Risk CD33+ AML/MDS/JMML [Phase 1]
Phase 1 trial evaluating allogeneic stem cell transplantation in high-risk CD33+ acute myeloid leukemia, myelodysplastic syndrome, and juven…
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CLINICAL_TRIALS trial_result · 2014-10-31Clinical Trial Update: A Study of Withdrawal of Immunosuppression and Donor Lymphocyte Infusions Following Allogeneic Transplant for Pediatric Hematologic Malignancies [Phase 2]
Phase 2 trial evaluating withdrawal of immunosuppression and donor lymphocyte infusions after allogeneic transplant in pediatric hematologic…
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CLINICAL_TRIALS trial_result · 2014-04-24Clinical Trial Update: Pilot Study of Expanded, Donor Natural Killer Cell Infusions for Refractory Non-B Lineage Hematologic Malignancies and Solid Tumors [Phase 1]
Phase 1 pilot study evaluating donor-derived natural killer cell infusions for refractory non-B lineage hematologic cancers and solid tumors…
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CLINICAL_TRIALS trial_result · 2013-07-16Clinical Trial Update: Pilot Study of Haploidentical Natural Killer Cell Infusions for Poor Prognosis Non-AML Hematologic Malignancies [Phase 1]
Phase 1 pilot study evaluating haploidentical natural killer cell infusions for poor-prognosis non-AML hematologic malignancies has complete…
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CLINICAL_TRIALS trial_result · 2013-04-11Clinical Trial Update: Combination Chemotherapy Followed By Donor Bone Marrow or Umbilical Cord Blood Transplant in Treating Children With Newly Diagnosed Juvenile Myelomonocytic Leukemia [Phase 2]
A Phase 2 study evaluating initial combination chemotherapy followed by donor bone marrow or umbilical cord blood transplantation in childre…
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CLINICAL_TRIALS trial_result · 2012-03-02Clinical Trial Update: Cytosine Arabinoside and Mitoxantrone for Patients With Juvenile Myelomonocytic Leukemia Receiving Repeat Stem Cell Transplantation [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating cytosine arabinoside and mitoxantrone in juvenile myelomonocytic leukemia patients undergoing repeat s…
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CLINICAL_TRIALS trial_result · 2010-12-02Clinical Trial Update: Etanercept (Enbrel) for Juvenile Myelomonocytic Leukemia [Phase 2]
A Phase 2 trial of etanercept (Enbrel) for Juvenile myelomonocytic leukemia was terminated. Results were posted in 2010.
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CLINICAL_TRIALS trial_result · 2009-02-13Clinical Trial Update: Haploidentical Stem Cell Transplant for Treatment Refractory Hematological Malignancies [Phase 2]
A Phase 2 clinical trial from St. Jude evaluated haploidentical hematopoietic stem cell transplantation for treatment-refractory hematologic…
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CLINICAL_TRIALS trial_result · 2009-01-29Clinical Trial Update: Haploidentical Stem Cell Transplantation for Patients With Hematologic Malignancies [Phase 3]
This document reports a Phase 3 clinical trial evaluating haploidentical hematopoietic stem cell transplantation in patients with hematologi…
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CLINICAL_TRIALS trial_result · 2009-01-29Clinical Trial Update: Stem Cell Transplantation for Patients With Hematologic Malignancies [Phase 3]
A Phase 3 clinical trial evaluating stem cell transplantation for hematologic malignancies has completed. The study covered several conditio…