Irritable Bowel Syndrome with Constipation
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-04Clinical Trial Update: Study to Assess Safety and Efficacy of Tenapanor for Treatment of IBS-C in Pediatric Patients 12 to Less Than 18 Years [Phase 3]
A Phase 3 pediatric trial assessing safety and efficacy of tenapanor for irritable bowel syndrome with constipation (IBS-C) in patients aged…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: MOWOOT Device Treatment for Adults With Chronic Constipation [NA]
The clinical trial update reports completion of a study evaluating the MOWOOT device for adults with chronic constipation and related condit…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Electro-acupuncture for Irritable Bowel Syndrome With Constipation [NA]
A clinical trial update indicates electro-acupoint therapy is being studied for irritable bowel syndrome with constipation. The study is cur…
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: Effect of Tenapanor on the Metagenomics and Metabolomics of Patients With Irritable Bowel Syndrome With Constipation [Phase 4]
A Phase 4 study completed evaluating the effect of tenapanor on the gut metagenome and metabolome in patients with irritable bowel syndrome …
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: "Efficacy and Safety of Linaclotide in Chronic Constipation" [Phase 4]
Phase 4 trial evaluating the efficacy and safety of linaclotide for chronic constipation is not yet recruiting. The study sponsor is Md Mehe…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Soluble and Osmotic Fibre (SOLOS) Diet for Constipation
The SOLOS Diet trial investigates soluble and osmotic fiber as a treatment for constipation. The study status is NOT_YET_RECRUITING.
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: A Study of Virtual Reality and Linaclotide for IBS-C [NA]
A Mayo Clinic study is exploring whether virtual reality plus the drug linaclotide can help patients with irritable bowel syndrome with cons…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Study to Assess Safety and Efficacy of Tenapanor for Treatment of IBS-C in Pediatric Patients 12 to Less Than 18 Years [Phase 3]
A Phase 3 clinical trial is evaluating the safety and efficacy of tenapanor for irritable bowel syndrome with constipation in pediatric pati…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Safety Study of Tenapanor for the Treatment of Pediatric Patients (6 to Less Than 18 Years Old) With IBS-C [Phase 3]
This clinical trial update outlines a Phase 3 safety study of tenapanor in pediatric patients aged 6 to under 18 with irritable bowel syndro…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: 4-Week, Multi-center Dose-Ranging Study for the IBS-C in Pts. 6 to <12 Yrs [Phase 2]
A Phase 2, multi-center 4-week dose-ranging trial evaluating tenapanor for irritable bowel syndrome with constipation in children aged 6 to …
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Long-term Safety of Linaclotide in Pediatric Participants With FC or IBS-C [Phase 3]
Phase 3 pediatric trial evaluating long-term safety of linaclotide for functional constipation or irritable bowel syndrome with constipation…
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CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: Efficacy and Safety of Plecanatide in Children 6 to <18 Years With Irritable Bowel Syndrome With Constipation (IBS-C) [Phase 2]
Phase 2 trial evaluating plecanatide in children aged 6 to under 18 with irritable bowel syndrome with constipation has completed and result…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Single-center Exploratory Study of the Intestinal Microbiota in Patients Treated for Irritable Bowel Syndrome With Predominant Constipation and Methane Production
A single-center exploratory clinical trial assessing the intestinal microbiota in patients treated for irritable bowel syndrome with constip…
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FDA label_change · 2025-11-04FDA Approved: LINZESS — Supplemental Application (Allergan, Inc.)
FDA supplemental application for Linzess (linaclotide) submitted by Allergan to modify labeling.
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Effect of Consuming a Nutraceutical Composition on Signs and Symptoms in Adult Patients With Irritable Bowel Syndrome [NA]
This is an ongoing clinical trial evaluating a nutraceutical composition for effects on signs and symptoms in adults with irritable bowel sy…
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: The Beneficial Effects on the Intestinal Function of a Food Supplement Based on an Extract of Green Tea and a Pool of Probiotics in Subjects With Irritable Bowel Syndrome With Predominance of Constipation [NA]
A clinical trial is evaluating whether a food supplement made from green tea extract and a probiotic pool improves intestinal function in in…
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FDA approval · 2025-05-20FDA Approved: IBSRELA — Supplemental Application (Ardelyx, Inc.)
The FDA approved a supplemental application for IBSRELA (tenapanor hydrochloride) submitted by Ardelyx, Inc., under NDA 211801.
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CLINICAL_TRIALS trial_result · 2025-04-25Clinical Trial Update: The Effect of Inulin Supplementation in Individuals With IBS-C [NA]
A completed clinical trial evaluating the effect of inulin supplementation in individuals with Irritable Bowel Syndrome, including IBS with …
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: Fecal Microbiota Transplantation to Relieve Symptoms of Irritable Bowel Syndrome With Constipation [NA]
A clinical trial is ongoing to evaluate fecal microbiota transplantation for relief of symptoms in irritable bowel syndrome with constipatio…
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: Low FODMAP Plus PEG 3350 for the Treatment of Patients with Irritable Bowel Syndrome-Constipation [NA]
A clinical trial update announcing recruitment for a study evaluating adding polyethylene glycol 3350 to a low FODMAP diet for irritable bow…
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: Efficacy of Chatbot for Irritable Bowel Syndrome (IBS) Patients [NA]
A clinical trial update shows ongoing enrollment for a study assessing the efficacy of a chatbot intervention in patients with various forms…
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FDA approval · 2025-01-10FDA Approved: IBSRELA — Supplemental Application (Ardelyx, Inc.)
FDA approved a supplemental application for IBSRELA (tenapanor hydrochloride) from Ardelyx, Inc.
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FDA approval · 2025-01-02FDA Approved: LUBIPROSTONE — Original Application (Camber Pharmaceuticals, Inc.)
FDA approved Camber Pharmaceuticals' original generic application for lubiprostone to treat chronic idiopathic constipation, opioid-induced …
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: Linaclotide Safety and Efficacy in Pediatric Participants, 6 to 17 Years of Age, With Irritable Bowel Syndrome With Constipation (IBS-C) or Functional Constipation (FC) [Phase 3]
A Phase 3 pediatric trial evaluating the safety and efficacy of linaclotide in children aged 6 to 17 with functional constipation or irritab…
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: Phase III Study to Evaluate the Efficacy and Safety of ASP0456 in Patients With Constipation Predominant Irritable Bowel Syndrome [Phase 3]
Phase 3 study evaluating the efficacy and safety of ASP0456 for Irritable bowel syndrome with constipation has completed.